Growth rate-corrected (GR) dose-response metrics across a panel of 71 breast cancer cell lines treated with a library of small molecule and antibody perturbagens. Dataset 1 of 4: Relative cell counts and normalized growth rate inhibition values across technical replicates. - Dataset (ID:20268)
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| Cell | Clinical Subtype | Transcriptional Subtype | Small Molecule | Antibody | Perturbagen Target | Perturbagen Class | Perturbagen Concentration | Perturbagen Conc Unit | Biological Replicate ID | Relative Cell Count | Normalized Growth Rate Inhibition Value | Nominal Division Rate |
|---|---|---|---|---|---|---|---|---|---|---|---|---|
| SUM229PE | TNBC | - | PS-1145 | IKK | NFKB | 0.121 | uM | 7535.065 | 0.9733 | 0.9386 | 0.8663 | |
| SUM229PE | TNBC | - | PS-1145 | IKK | NFKB | 0.606 | uM | 7535.065 | 0.9726 | 0.9368 | 0.8663 | |
| SUM229PE | TNBC | - | PS-1145 | IKK | NFKB | 3.03 | uM | 7535.065 | 1.0391 | 1.0904 | 0.8663 | |
| SUM229PE | TNBC | - | PS-1145 | IKK | NFKB | 15.2 | uM | 7535.065 | 0.9907 | 0.9785 | 0.8663 | |
| SUM229PE | TNBC | - | PS-1145 | IKK | NFKB | 75.8 | uM | 7535.065 | 1.0161 | 1.0371 | 0.8663 | |
| SUM229PE | TNBC | - | PS-1145 | IKK | NFKB | 379 | uM | 7535.065 | 0.9391 | 0.8601 | 0.8663 | |
| SUM229PE | TNBC | - | PS-1145 | IKK | NFKB | 1890 | uM | 7535.065 | 0.9474 | 0.8790 | 0.8663 | |
| SUM229PE | TNBC | - | PS-1145 | IKK | NFKB | 0.00485 | uM | 7537.065 | 0.9460 | 0.9414 | 1.8673 | |
| SUM229PE | TNBC | - | PS-1145 | IKK | NFKB | 0.0243 | uM | 7537.065 | 0.9821 | 0.9807 | 1.8673 | |
| SUM229PE | TNBC | - | PS-1145 | IKK | NFKB | 0.121 | uM | 7537.065 | 0.9563 | 0.9527 | 1.8673 | |
| SUM229PE | TNBC | - | PS-1145 | IKK | NFKB | 0.606 | uM | 7537.065 | 0.9968 | 0.9966 | 1.8673 | |
| SUM229PE | TNBC | - | PS-1145 | IKK | NFKB | 3.03 | uM | 7537.065 | 0.9716 | 0.9694 | 1.8673 | |
| SUM229PE | TNBC | - | PS-1145 | IKK | NFKB | 15.2 | uM | 7537.065 | 0.9877 | 0.9868 | 1.8673 | |
| SUM229PE | TNBC | - | PS-1145 | IKK | NFKB | 75.8 | uM | 7537.065 | 0.9782 | 0.9766 | 1.8673 | |
| SUM229PE | TNBC | - | PS-1145 | IKK | NFKB | 379 | uM | 7537.065 | 1.0207 | 1.0221 | 1.8673 | |
| SUM229PE | TNBC | - | PS-1145 | IKK | NFKB | 1890 | uM | 7537.065 | 0.9500 | 0.9458 | 1.8673 | |
| SUM52PE | HR+ | Luminal | PS-1145 | IKK | NFKB | 0.00485 | uM | 7539.065 | 0.9925 | 0.9894 | 1.4108 | |
| SUM52PE | HR+ | Luminal | PS-1145 | IKK | NFKB | 0.0243 | uM | 7539.065 | 0.8741 | 0.8181 | 1.4108 | |
| SUM52PE | HR+ | Luminal | PS-1145 | IKK | NFKB | 0.121 | uM | 7539.065 | 0.9452 | 0.9217 | 1.4108 | |
| SUM52PE | HR+ | Luminal | PS-1145 | IKK | NFKB | 0.606 | uM | 7539.065 | 0.9347 | 0.9065 | 1.4108 | |
| SUM52PE | HR+ | Luminal | PS-1145 | IKK | NFKB | 3.03 | uM | 7539.065 | 0.9795 | 0.9708 | 1.4108 | |
| SUM52PE | HR+ | Luminal | PS-1145 | IKK | NFKB | 15.2 | uM | 7539.065 | 0.8613 | 0.7992 | 1.4108 | |
| SUM52PE | HR+ | Luminal | PS-1145 | IKK | NFKB | 75.8 | uM | 7539.065 | 0.9532 | 0.9332 | 1.4108 | |
| SUM52PE | HR+ | Luminal | PS-1145 | IKK | NFKB | 379 | uM | 7539.065 | 0.6499 | 0.4736 | 1.4108 | |
| SUM52PE | HR+ | Luminal | PS-1145 | IKK | NFKB | 1890 | uM | 7539.065 | 0.6681 | 0.5028 | 1.4108 |