Growth rate-corrected (GR) dose-response metrics across a panel of 71 breast cancer cell lines treated with a library of small molecule and antibody perturbagens. Dataset 1 of 4: Relative cell counts and normalized growth rate inhibition values across technical replicates. - Dataset (ID:20268)
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| Cell | Clinical Subtype | Transcriptional Subtype | Small Molecule | Antibody | Perturbagen Target | Perturbagen Class | Perturbagen Concentration | Perturbagen Conc Unit | Biological Replicate ID | Relative Cell Count | Normalized Growth Rate Inhibition Value | Nominal Division Rate |
|---|---|---|---|---|---|---|---|---|---|---|---|---|
| HCC1395 | TNBC | Basal B | PD184352 | MEK | MAPK | 0.0533 | uM | 12084.155 | 1.0532 | 1.0816 | 1.2955 | |
| HCC1395 | TNBC | Basal B | PD184352 | MEK | MAPK | 0.267 | uM | 12084.155 | 0.9792 | 0.9678 | 1.2955 | |
| HCC1395 | TNBC | Basal B | PD184352 | MEK | MAPK | 0.267 | uM | 12084.155 | 0.9792 | 0.9678 | 1.2955 | |
| HCC1395 | TNBC | Basal B | PD184352 | MEK | MAPK | 1.33 | uM | 12084.155 | 1.0341 | 1.0524 | 1.2955 | |
| HCC1395 | TNBC | Basal B | PD184352 | MEK | MAPK | 1.33 | uM | 12084.155 | 1.0341 | 1.0524 | 1.2955 | |
| HCC1395 | TNBC | Basal B | PD184352 | MEK | MAPK | 6.67 | uM | 12084.155 | 0.9544 | 0.9292 | 1.2955 | |
| HCC1395 | TNBC | Basal B | PD184352 | MEK | MAPK | 6.67 | uM | 12084.155 | 0.9544 | 0.9292 | 1.2955 | |
| HCC1395 | TNBC | Basal B | PD184352 | MEK | MAPK | 33.3 | uM | 12084.155 | 0.9792 | 0.9678 | 1.2955 | |
| HCC1395 | TNBC | Basal B | PD184352 | MEK | MAPK | 33.3 | uM | 12084.155 | 0.9792 | 0.9678 | 1.2955 | |
| HCC1419 | HER2amp | Luminal | PD184352 | MEK | MAPK | 0.0000853 | uM | 12001.155 | 1.0091 | 1.0305 | 0.5973 | |
| HCC1419 | HER2amp | Luminal | PD184352 | MEK | MAPK | 0.0000853 | uM | 12001.155 | 1.0091 | 1.0305 | 0.5973 | |
| HCC1419 | HER2amp | Luminal | PD184352 | MEK | MAPK | 0.000427 | uM | 12001.155 | 0.9805 | 0.9350 | 0.5973 | |
| HCC1419 | HER2amp | Luminal | PD184352 | MEK | MAPK | 0.000427 | uM | 12001.155 | 0.9805 | 0.9350 | 0.5973 | |
| HCC1419 | HER2amp | Luminal | PD184352 | MEK | MAPK | 0.00213 | uM | 12001.155 | 0.9526 | 0.8439 | 0.5973 | |
| HCC1419 | HER2amp | Luminal | PD184352 | MEK | MAPK | 0.00213 | uM | 12001.155 | 0.9526 | 0.8439 | 0.5973 | |
| HCC1419 | HER2amp | Luminal | PD184352 | MEK | MAPK | 0.0107 | uM | 12001.155 | 0.9314 | 0.7757 | 0.5973 | |
| HCC1419 | HER2amp | Luminal | PD184352 | MEK | MAPK | 0.0107 | uM | 12001.155 | 0.9314 | 0.7757 | 0.5973 | |
| HCC1419 | HER2amp | Luminal | PD184352 | MEK | MAPK | 0.0533 | uM | 12001.155 | 0.9721 | 0.9074 | 0.5973 | |
| HCC1419 | HER2amp | Luminal | PD184352 | MEK | MAPK | 0.0533 | uM | 12001.155 | 0.9721 | 0.9074 | 0.5973 | |
| HCC1419 | HER2amp | Luminal | PD184352 | MEK | MAPK | 0.267 | uM | 12001.155 | 0.9676 | 0.8928 | 0.5973 | |
| HCC1419 | HER2amp | Luminal | PD184352 | MEK | MAPK | 0.267 | uM | 12001.155 | 0.9676 | 0.8928 | 0.5973 | |
| HCC1419 | HER2amp | Luminal | PD184352 | MEK | MAPK | 1.33 | uM | 12001.155 | 0.9231 | 0.7493 | 0.5973 | |
| HCC1419 | HER2amp | Luminal | PD184352 | MEK | MAPK | 1.33 | uM | 12001.155 | 0.9231 | 0.7493 | 0.5973 | |
| HCC1419 | HER2amp | Luminal | PD184352 | MEK | MAPK | 6.67 | uM | 12001.155 | 0.9573 | 0.8592 | 0.5973 | |
| HCC1419 | HER2amp | Luminal | PD184352 | MEK | MAPK | 6.67 | uM | 12001.155 | 0.9573 | 0.8592 | 0.5973 |