Growth rate-corrected (GR) dose-response metrics across a panel of 71 breast cancer cell lines treated with a library of small molecule and antibody perturbagens. Dataset 1 of 4: Relative cell counts and normalized growth rate inhibition values across technical replicates. - Dataset (ID:20268)
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| Cell | Clinical Subtype | Transcriptional Subtype | Small Molecule | Antibody | Perturbagen Target | Perturbagen Class | Perturbagen Concentration | Perturbagen Conc Unit | Biological Replicate ID | Relative Cell Count | Normalized Growth Rate Inhibition Value | Nominal Division Rate |
|---|---|---|---|---|---|---|---|---|---|---|---|---|
| HCC1419 | HER2amp | Luminal | PD184352 | MEK | MAPK | 33.3 | uM | 12001.155 | 0.8886 | 0.6410 | 0.5973 | |
| HCC1419 | HER2amp | Luminal | PD184352 | MEK | MAPK | 33.3 | uM | 12001.155 | 0.8886 | 0.6410 | 0.5973 | |
| HCC1428 | HR+ | Luminal | PD184352 | MEK | MAPK | 0.000171 | uM | 10693.146 | 0.9752 | 0.9438 | 0.8826 | |
| HCC1428 | HR+ | Luminal | PD184352 | MEK | MAPK | 0.000171 | uM | 10693.146 | 0.9752 | 0.9438 | 0.8826 | |
| HCC1428 | HR+ | Luminal | PD184352 | MEK | MAPK | 0.000853 | uM | 10693.146 | 0.9821 | 0.9595 | 0.8826 | |
| HCC1428 | HR+ | Luminal | PD184352 | MEK | MAPK | 0.000853 | uM | 10693.146 | 0.9821 | 0.9595 | 0.8826 | |
| HCC1428 | HR+ | Luminal | PD184352 | MEK | MAPK | 0.00427 | uM | 10693.146 | 0.9920 | 0.9819 | 0.8826 | |
| HCC1428 | HR+ | Luminal | PD184352 | MEK | MAPK | 0.00427 | uM | 10693.146 | 0.9920 | 0.9819 | 0.8826 | |
| HCC1428 | HR+ | Luminal | PD184352 | MEK | MAPK | 0.0213 | uM | 10693.146 | 1.0312 | 1.0709 | 0.8826 | |
| HCC1428 | HR+ | Luminal | PD184352 | MEK | MAPK | 0.0213 | uM | 10693.146 | 1.0312 | 1.0709 | 0.8826 | |
| HCC1428 | HR+ | Luminal | PD184352 | MEK | MAPK | 0.107 | uM | 10693.146 | 1.0074 | 1.0169 | 0.8826 | |
| HCC1428 | HR+ | Luminal | PD184352 | MEK | MAPK | 0.107 | uM | 10693.146 | 1.0074 | 1.0169 | 0.8826 | |
| HCC1428 | HR+ | Luminal | PD184352 | MEK | MAPK | 0.533 | uM | 10693.146 | 0.9701 | 0.9323 | 0.8826 | |
| HCC1428 | HR+ | Luminal | PD184352 | MEK | MAPK | 0.533 | uM | 10693.146 | 0.9701 | 0.9323 | 0.8826 | |
| HCC1428 | HR+ | Luminal | PD184352 | MEK | MAPK | 2.67 | uM | 10693.146 | 0.9768 | 0.9476 | 0.8826 | |
| HCC1428 | HR+ | Luminal | PD184352 | MEK | MAPK | 2.67 | uM | 10693.146 | 0.9768 | 0.9476 | 0.8826 | |
| HCC1428 | HR+ | Luminal | PD184352 | MEK | MAPK | 13.3 | uM | 10693.146 | 0.9522 | 0.8920 | 0.8826 | |
| HCC1428 | HR+ | Luminal | PD184352 | MEK | MAPK | 13.3 | uM | 10693.146 | 0.9522 | 0.8920 | 0.8826 | |
| HCC1428 | HR+ | Luminal | PD184352 | MEK | MAPK | 66.7 | uM | 10693.146 | 0.8734 | 0.7157 | 0.8826 | |
| HCC1428 | HR+ | Luminal | PD184352 | MEK | MAPK | 66.7 | uM | 10693.146 | 0.8734 | 0.7157 | 0.8826 | |
| HCC1428 | HR+ | Luminal | PD184352 | MEK | MAPK | 0.0000853 | uM | 11936.155 | 0.9696 | 0.9176 | 0.7332 | |
| HCC1428 | HR+ | Luminal | PD184352 | MEK | MAPK | 0.0000853 | uM | 11936.155 | 0.9696 | 0.9176 | 0.7332 | |
| HCC1428 | HR+ | Luminal | PD184352 | MEK | MAPK | 0.000427 | uM | 11936.155 | 0.9295 | 0.8103 | 0.7332 | |
| HCC1428 | HR+ | Luminal | PD184352 | MEK | MAPK | 0.000427 | uM | 11936.155 | 0.9295 | 0.8103 | 0.7332 | |
| HCC1428 | HR+ | Luminal | PD184352 | MEK | MAPK | 0.00213 | uM | 11936.155 | 0.9633 | 0.9007 | 0.7332 |