Growth rate-corrected (GR) dose-response metrics across a panel of 71 breast cancer cell lines treated with a library of small molecule and antibody perturbagens. Dataset 1 of 4: Relative cell counts and normalized growth rate inhibition values across technical replicates. - Dataset (ID:20268)
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| Cell | Clinical Subtype | Transcriptional Subtype | Small Molecule | Antibody | Perturbagen Target | Perturbagen Class | Perturbagen Concentration | Perturbagen Conc Unit | Biological Replicate ID | Relative Cell Count | Normalized Growth Rate Inhibition Value | Nominal Division Rate |
|---|---|---|---|---|---|---|---|---|---|---|---|---|
| SUM149PT | TNBC | Basal B | Oxaliplatin | DNA cross-linker | DNA cross-linker | 0.00161 | uM | 7917.075 | 0.9485 | 0.9656 | 3.0479 | |
| SUM149PT | TNBC | Basal B | Oxaliplatin | DNA cross-linker | DNA cross-linker | 0.00806 | uM | 7917.075 | 0.9865 | 0.9911 | 3.0479 | |
| SUM149PT | TNBC | Basal B | Oxaliplatin | DNA cross-linker | DNA cross-linker | 0.0403 | uM | 7917.075 | 0.9674 | 0.9783 | 3.0479 | |
| SUM149PT | TNBC | Basal B | Oxaliplatin | DNA cross-linker | DNA cross-linker | 0.201 | uM | 7917.075 | 0.8788 | 0.9170 | 3.0479 | |
| SUM149PT | TNBC | Basal B | Oxaliplatin | DNA cross-linker | DNA cross-linker | 1.01 | uM | 7917.075 | 0.5290 | 0.6229 | 3.0479 | |
| SUM149PT | TNBC | Basal B | Oxaliplatin | DNA cross-linker | DNA cross-linker | 5.04 | uM | 7917.075 | 0.4351 | 0.5221 | 3.0479 | |
| SUM149PT | TNBC | Basal B | Oxaliplatin | DNA cross-linker | DNA cross-linker | 25.2 | uM | 7917.075 | 0.1042 | -0.0476 | 3.0479 | |
| SUM149PT | TNBC | Basal B | Oxaliplatin | DNA cross-linker | DNA cross-linker | 126 | uM | 7917.075 | 0.0038 | -0.6790 | 3.0479 | |
| SUM149PT | TNBC | Basal B | Oxaliplatin | DNA cross-linker | DNA cross-linker | 629 | uM | 7917.075 | 0.0024 | -0.7220 | 3.0479 | |
| SUM149PT | TNBC | Basal B | Oxaliplatin | DNA cross-linker | DNA cross-linker | 0.00161 | uM | 9830.011 | 1.0808 | 1.0762 | 2.0792 | |
| SUM149PT | TNBC | Basal B | Oxaliplatin | DNA cross-linker | DNA cross-linker | 0.00805 | uM | 9830.011 | 1.0620 | 1.0587 | 2.0792 | |
| SUM149PT | TNBC | Basal B | Oxaliplatin | DNA cross-linker | DNA cross-linker | 0.0403 | uM | 9830.011 | 1.0068 | 1.0065 | 2.0792 | |
| SUM149PT | TNBC | Basal B | Oxaliplatin | DNA cross-linker | DNA cross-linker | 0.201 | uM | 9830.011 | 0.7921 | 0.7879 | 2.0792 | |
| SUM149PT | TNBC | Basal B | Oxaliplatin | DNA cross-linker | DNA cross-linker | 1.01 | uM | 9830.011 | 0.5694 | 0.5254 | 2.0792 | |
| SUM149PT | TNBC | Basal B | Oxaliplatin | DNA cross-linker | DNA cross-linker | 5.03 | uM | 9830.011 | 0.4689 | 0.3894 | 2.0792 | |
| SUM149PT | TNBC | Basal B | Oxaliplatin | DNA cross-linker | DNA cross-linker | 25.2 | uM | 9830.011 | 0.1985 | -0.0810 | 2.0792 | |
| SUM149PT | TNBC | Basal B | Oxaliplatin | DNA cross-linker | DNA cross-linker | 126 | uM | 9830.011 | 0.0109 | -0.7729 | 2.0792 | |
| SUM149PT | TNBC | Basal B | Oxaliplatin | DNA cross-linker | DNA cross-linker | 629 | uM | 9830.011 | 0.0105 | -0.7766 | 2.0792 | |
| SUM159PT | TNBC | Basal B | Oxaliplatin | DNA cross-linker | DNA cross-linker | 0.00161 | uM | 7918.011 | 0.9792 | 0.9855 | 2.8897 | |
| SUM159PT | TNBC | Basal B | Oxaliplatin | DNA cross-linker | DNA cross-linker | 0.00805 | uM | 7918.011 | 0.9759 | 0.9832 | 2.8897 | |
| SUM159PT | TNBC | Basal B | Oxaliplatin | DNA cross-linker | DNA cross-linker | 0.0403 | uM | 7918.011 | 1.0172 | 1.0118 | 2.8897 | |
| SUM159PT | TNBC | Basal B | Oxaliplatin | DNA cross-linker | DNA cross-linker | 0.201 | uM | 7918.011 | 0.9291 | 0.9497 | 2.8897 | |
| SUM159PT | TNBC | Basal B | Oxaliplatin | DNA cross-linker | DNA cross-linker | 1.01 | uM | 7918.011 | 0.7173 | 0.7828 | 2.8897 | |
| SUM159PT | TNBC | Basal B | Oxaliplatin | DNA cross-linker | DNA cross-linker | 5.03 | uM | 7918.011 | 0.3560 | 0.3990 | 2.8897 | |
| SUM159PT | TNBC | Basal B | Oxaliplatin | DNA cross-linker | DNA cross-linker | 25.2 | uM | 7918.011 | 0.1325 | -0.0064 | 2.8897 |