Growth rate-corrected (GR) dose-response metrics across a panel of 71 breast cancer cell lines treated with a library of small molecule and antibody perturbagens. Dataset 1 of 4: Relative cell counts and normalized growth rate inhibition values across technical replicates. - Dataset (ID:20268)
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| Cell | Clinical Subtype | Transcriptional Subtype | Small Molecule | Antibody | Perturbagen Target | Perturbagen Class | Perturbagen Concentration | Perturbagen Conc Unit | Biological Replicate ID | Relative Cell Count | Normalized Growth Rate Inhibition Value | Nominal Division Rate |
|---|---|---|---|---|---|---|---|---|---|---|---|---|
| HCC3153 | TNBC | Basal A | Oxaliplatin | DNA cross-linker | DNA cross-linker | 0.0403 | uM | 10056.021 | 0.9849 | 0.9658 | 0.8839 | |
| HCC3153 | TNBC | Basal A | Oxaliplatin | DNA cross-linker | DNA cross-linker | 0.201 | uM | 10056.021 | 0.9691 | 0.9302 | 0.8839 | |
| HCC3153 | TNBC | Basal A | Oxaliplatin | DNA cross-linker | DNA cross-linker | 1.01 | uM | 10056.021 | 0.9568 | 0.9026 | 0.8839 | |
| HCC3153 | TNBC | Basal A | Oxaliplatin | DNA cross-linker | DNA cross-linker | 5.03 | uM | 10056.021 | 0.7274 | 0.3952 | 0.8839 | |
| HCC3153 | TNBC | Basal A | Oxaliplatin | DNA cross-linker | DNA cross-linker | 25.2 | uM | 10056.021 | 0.5820 | 0.0840 | 0.8839 | |
| HCC3153 | TNBC | Basal A | Oxaliplatin | DNA cross-linker | DNA cross-linker | 126 | uM | 10056.021 | 0.1401 | -0.7835 | 0.8839 | |
| HCC3153 | TNBC | Basal A | Oxaliplatin | DNA cross-linker | DNA cross-linker | 629 | uM | 10056.021 | 0.0665 | -0.9069 | 0.8839 | |
| HCC38 | TNBC | Basal B | Oxaliplatin | DNA cross-linker | DNA cross-linker | 0.00161 | uM | 9028.075 | 1.2495 | 1.8971 | 0.6011 | |
| HCC38 | TNBC | Basal B | Oxaliplatin | DNA cross-linker | DNA cross-linker | 0.00806 | uM | 9028.075 | 1.0404 | 1.1363 | 0.6011 | |
| HCC38 | TNBC | Basal B | Oxaliplatin | DNA cross-linker | DNA cross-linker | 0.0403 | uM | 9028.075 | 1.1084 | 1.3736 | 0.6011 | |
| HCC38 | TNBC | Basal B | Oxaliplatin | DNA cross-linker | DNA cross-linker | 0.201 | uM | 9028.075 | 0.9960 | 0.9867 | 0.6011 | |
| HCC38 | TNBC | Basal B | Oxaliplatin | DNA cross-linker | DNA cross-linker | 1.01 | uM | 9028.075 | 0.9036 | 0.6897 | 0.6011 | |
| HCC38 | TNBC | Basal B | Oxaliplatin | DNA cross-linker | DNA cross-linker | 5.04 | uM | 9028.075 | 0.6458 | -0.0337 | 0.6011 | |
| HCC38 | TNBC | Basal B | Oxaliplatin | DNA cross-linker | DNA cross-linker | 25.2 | uM | 9028.075 | 0.4596 | -0.4513 | 0.6011 | |
| HCC38 | TNBC | Basal B | Oxaliplatin | DNA cross-linker | DNA cross-linker | 126 | uM | 9028.075 | 0.1092 | -0.9498 | 0.6011 | |
| HCC38 | TNBC | Basal B | Oxaliplatin | DNA cross-linker | DNA cross-linker | 629 | uM | 9028.075 | 0.0756 | -0.9728 | 0.6011 | |
| HCC38 | TNBC | Basal B | Oxaliplatin | DNA cross-linker | DNA cross-linker | 0.00161 | uM | 9453.011 | 1.5366 | 2.4758 | 0.7773 | |
| HCC38 | TNBC | Basal B | Oxaliplatin | DNA cross-linker | DNA cross-linker | 0.00805 | uM | 9453.011 | 1.4816 | 2.3165 | 0.7773 | |
| HCC38 | TNBC | Basal B | Oxaliplatin | DNA cross-linker | DNA cross-linker | 0.0403 | uM | 9453.011 | 1.5377 | 2.4790 | 0.7773 | |
| HCC38 | TNBC | Basal B | Oxaliplatin | DNA cross-linker | DNA cross-linker | 0.201 | uM | 9453.011 | 1.5258 | 2.4445 | 0.7773 | |
| HCC38 | TNBC | Basal B | Oxaliplatin | DNA cross-linker | DNA cross-linker | 1.01 | uM | 9453.011 | 1.3488 | 1.9390 | 0.7773 | |
| HCC38 | TNBC | Basal B | Oxaliplatin | DNA cross-linker | DNA cross-linker | 5.03 | uM | 9453.011 | 0.8664 | 0.6629 | 0.7773 | |
| HCC38 | TNBC | Basal B | Oxaliplatin | DNA cross-linker | DNA cross-linker | 25.2 | uM | 9453.011 | 0.4667 | -0.2497 | 0.7773 | |
| HCC38 | TNBC | Basal B | Oxaliplatin | DNA cross-linker | DNA cross-linker | 126 | uM | 9453.011 | 0.0699 | -0.9348 | 0.7773 | |
| HCC38 | TNBC | Basal B | Oxaliplatin | DNA cross-linker | DNA cross-linker | 629 | uM | 9453.011 | 0.0238 | -0.9837 | 0.7773 |