Growth rate-corrected (GR) dose-response metrics across a panel of 71 breast cancer cell lines treated with a library of small molecule and antibody perturbagens. Dataset 1 of 4: Relative cell counts and normalized growth rate inhibition values across technical replicates. - Dataset (ID:20268)
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| Cell | Clinical Subtype | Transcriptional Subtype | Small Molecule | Antibody | Perturbagen Target | Perturbagen Class | Perturbagen Concentration | Perturbagen Conc Unit | Biological Replicate ID | Relative Cell Count | Normalized Growth Rate Inhibition Value | Nominal Division Rate |
|---|---|---|---|---|---|---|---|---|---|---|---|---|
| SUM159PT | TNBC | Basal B | PD173074 | FGFR1/3 | RTK | 0.0000853 | uM | 7531.093 | 0.9437 | 0.9681 | 3.5995 | |
| SUM159PT | TNBC | Basal B | PD173074 | FGFR1/3 | RTK | 0.000427 | uM | 7531.093 | 0.9765 | 0.9868 | 3.5995 | |
| SUM159PT | TNBC | Basal B | PD173074 | FGFR1/3 | RTK | 0.00213 | uM | 7531.093 | 0.9913 | 0.9951 | 3.5995 | |
| SUM159PT | TNBC | Basal B | PD173074 | FGFR1/3 | RTK | 0.0107 | uM | 7531.093 | 0.9666 | 0.9812 | 3.5995 | |
| SUM159PT | TNBC | Basal B | PD173074 | FGFR1/3 | RTK | 0.0533 | uM | 7531.093 | 0.9123 | 0.9496 | 3.5995 | |
| SUM159PT | TNBC | Basal B | PD173074 | FGFR1/3 | RTK | 0.267 | uM | 7531.093 | 0.8914 | 0.9372 | 3.5995 | |
| SUM159PT | TNBC | Basal B | PD173074 | FGFR1/3 | RTK | 1.33 | uM | 7531.093 | 0.8423 | 0.9069 | 3.5995 | |
| SUM159PT | TNBC | Basal B | PD173074 | FGFR1/3 | RTK | 6.67 | uM | 7531.093 | 0.4410 | 0.5931 | 3.5995 | |
| SUM159PT | TNBC | Basal B | PD173074 | FGFR1/3 | RTK | 33.3 | uM | 7531.093 | 0.0005 | -0.7611 | 3.5995 | |
| SUM159PT | TNBC | Basal B | PD173074 | FGFR1/3 | RTK | 0.000171 | uM | 10520.1 | 1.0302 | 1.0165 | 3.6151 | |
| SUM159PT | TNBC | Basal B | PD173074 | FGFR1/3 | RTK | 0.000853 | uM | 10520.1 | 0.9258 | 0.9578 | 3.6151 | |
| SUM159PT | TNBC | Basal B | PD173074 | FGFR1/3 | RTK | 0.00427 | uM | 10520.1 | 1.1328 | 1.0702 | 3.6151 | |
| SUM159PT | TNBC | Basal B | PD173074 | FGFR1/3 | RTK | 0.0213 | uM | 10520.1 | 1.0639 | 1.0345 | 3.6151 | |
| SUM159PT | TNBC | Basal B | PD173074 | FGFR1/3 | RTK | 0.107 | uM | 10520.1 | 1.1198 | 1.0636 | 3.6151 | |
| SUM159PT | TNBC | Basal B | PD173074 | FGFR1/3 | RTK | 0.533 | uM | 10520.1 | 0.9178 | 0.9531 | 3.6151 | |
| SUM159PT | TNBC | Basal B | PD173074 | FGFR1/3 | RTK | 2.67 | uM | 10520.1 | 0.9551 | 0.9747 | 3.6151 | |
| SUM159PT | TNBC | Basal B | PD173074 | FGFR1/3 | RTK | 13.3 | uM | 10520.1 | 0.2076 | 0.2946 | 3.6151 | |
| SUM159PT | TNBC | Basal B | PD173074 | FGFR1/3 | RTK | 66.7 | uM | 10520.1 | 0.0009 | -0.7137 | 3.6151 | |
| SUM225CWN | HER2amp | Basal A | PD173074 | FGFR1/3 | RTK | 0.000171 | uM | 10579.1 | 0.9811 | 0.9610 | 0.9677 | |
| SUM225CWN | HER2amp | Basal A | PD173074 | FGFR1/3 | RTK | 0.000853 | uM | 10579.1 | 1.0377 | 1.0780 | 0.9677 | |
| SUM225CWN | HER2amp | Basal A | PD173074 | FGFR1/3 | RTK | 0.00427 | uM | 10579.1 | 1.1171 | 1.2424 | 0.9677 | |
| SUM225CWN | HER2amp | Basal A | PD173074 | FGFR1/3 | RTK | 0.0213 | uM | 10579.1 | 1.1119 | 1.2318 | 0.9677 | |
| SUM225CWN | HER2amp | Basal A | PD173074 | FGFR1/3 | RTK | 0.107 | uM | 10579.1 | 0.9300 | 0.8555 | 0.9677 | |
| SUM225CWN | HER2amp | Basal A | PD173074 | FGFR1/3 | RTK | 0.533 | uM | 10579.1 | 0.9200 | 0.8348 | 0.9677 | |
| SUM225CWN | HER2amp | Basal A | PD173074 | FGFR1/3 | RTK | 2.67 | uM | 10579.1 | 0.9667 | 0.9313 | 0.9677 |