Growth rate-corrected (GR) dose-response metrics across a panel of 71 breast cancer cell lines treated with a library of small molecule and antibody perturbagens. Dataset 1 of 4: Relative cell counts and normalized growth rate inhibition values across technical replicates. - Dataset (ID:20268)
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| Cell | Clinical Subtype | Transcriptional Subtype | Small Molecule | Antibody | Perturbagen Target | Perturbagen Class | Perturbagen Concentration | Perturbagen Conc Unit | Biological Replicate ID | Relative Cell Count | Normalized Growth Rate Inhibition Value | Nominal Division Rate |
|---|---|---|---|---|---|---|---|---|---|---|---|---|
| HCC1395 | TNBC | Basal B | MG-132 | Proteasome | Proteasome | 0.000853 | uM | 12000.145 | 0.9579 | 0.8634 | 0.6084 | |
| HCC1395 | TNBC | Basal B | MG-132 | Proteasome | Proteasome | 0.00427 | uM | 12000.145 | 0.9593 | 0.8680 | 0.6084 | |
| HCC1395 | TNBC | Basal B | MG-132 | Proteasome | Proteasome | 0.00427 | uM | 12000.145 | 0.9593 | 0.8680 | 0.6084 | |
| HCC1395 | TNBC | Basal B | MG-132 | Proteasome | Proteasome | 0.0213 | uM | 12000.145 | 0.9569 | 0.8601 | 0.6084 | |
| HCC1395 | TNBC | Basal B | MG-132 | Proteasome | Proteasome | 0.0213 | uM | 12000.145 | 0.9569 | 0.8601 | 0.6084 | |
| HCC1395 | TNBC | Basal B | MG-132 | Proteasome | Proteasome | 0.107 | uM | 12000.145 | 0.9465 | 0.8271 | 0.6084 | |
| HCC1395 | TNBC | Basal B | MG-132 | Proteasome | Proteasome | 0.107 | uM | 12000.145 | 0.9465 | 0.8271 | 0.6084 | |
| HCC1395 | TNBC | Basal B | MG-132 | Proteasome | Proteasome | 0.533 | uM | 12000.145 | 0.3659 | -0.6169 | 0.6084 | |
| HCC1395 | TNBC | Basal B | MG-132 | Proteasome | Proteasome | 0.533 | uM | 12000.145 | 0.3659 | -0.6169 | 0.6084 | |
| HCC1395 | TNBC | Basal B | MG-132 | Proteasome | Proteasome | 2.67 | uM | 12000.145 | 0.1458 | -0.9156 | 0.6084 | |
| HCC1395 | TNBC | Basal B | MG-132 | Proteasome | Proteasome | 2.67 | uM | 12000.145 | 0.1458 | -0.9156 | 0.6084 | |
| HCC1395 | TNBC | Basal B | MG-132 | Proteasome | Proteasome | 13.3 | uM | 12000.145 | 0.1328 | -0.9276 | 0.6084 | |
| HCC1395 | TNBC | Basal B | MG-132 | Proteasome | Proteasome | 13.3 | uM | 12000.145 | 0.1328 | -0.9276 | 0.6084 | |
| HCC1395 | TNBC | Basal B | MG-132 | Proteasome | Proteasome | 66.7 | uM | 12000.145 | 0.1183 | -0.9401 | 0.6084 | |
| HCC1395 | TNBC | Basal B | MG-132 | Proteasome | Proteasome | 66.7 | uM | 12000.145 | 0.1183 | -0.9401 | 0.6084 | |
| HCC1395 | TNBC | Basal B | MG-132 | Proteasome | Proteasome | 0.000171 | uM | 12084.145 | 0.9849 | 0.9741 | 1.1692 | |
| HCC1395 | TNBC | Basal B | MG-132 | Proteasome | Proteasome | 0.000171 | uM | 12084.145 | 0.9849 | 0.9741 | 1.1692 | |
| HCC1395 | TNBC | Basal B | MG-132 | Proteasome | Proteasome | 0.000853 | uM | 12084.145 | 0.8940 | 0.8173 | 1.1692 | |
| HCC1395 | TNBC | Basal B | MG-132 | Proteasome | Proteasome | 0.000853 | uM | 12084.145 | 0.8940 | 0.8173 | 1.1692 | |
| HCC1395 | TNBC | Basal B | MG-132 | Proteasome | Proteasome | 0.00427 | uM | 12084.145 | 0.9767 | 0.9600 | 1.1692 | |
| HCC1395 | TNBC | Basal B | MG-132 | Proteasome | Proteasome | 0.00427 | uM | 12084.145 | 0.9767 | 0.9600 | 1.1692 | |
| HCC1395 | TNBC | Basal B | MG-132 | Proteasome | Proteasome | 0.0213 | uM | 12084.145 | 0.9426 | 0.9014 | 1.1692 | |
| HCC1395 | TNBC | Basal B | MG-132 | Proteasome | Proteasome | 0.0213 | uM | 12084.145 | 0.9426 | 0.9014 | 1.1692 | |
| HCC1395 | TNBC | Basal B | MG-132 | Proteasome | Proteasome | 0.107 | uM | 12084.145 | 0.9022 | 0.8316 | 1.1692 | |
| HCC1395 | TNBC | Basal B | MG-132 | Proteasome | Proteasome | 0.107 | uM | 12084.145 | 0.9022 | 0.8316 | 1.1692 |