Growth rate-corrected (GR) dose-response metrics across a panel of 71 breast cancer cell lines treated with a library of small molecule and antibody perturbagens. Dataset 1 of 4: Relative cell counts and normalized growth rate inhibition values across technical replicates. - Dataset (ID:20268)
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| Cell | Clinical Subtype | Transcriptional Subtype | Small Molecule | Antibody | Perturbagen Target | Perturbagen Class | Perturbagen Concentration | Perturbagen Conc Unit | Biological Replicate ID | Relative Cell Count | Normalized Growth Rate Inhibition Value | Nominal Division Rate |
|---|---|---|---|---|---|---|---|---|---|---|---|---|
| HCC1143 | TNBC | Basal A | MG-132 | Proteasome | Proteasome | 13.3 | uM | 14203.189 | 0.4570 | 0.2602 | 1.6955 | |
| HCC1143 | TNBC | Basal A | MG-132 | Proteasome | Proteasome | 13.3 | uM | 14203.189 | 0.4570 | 0.2602 | 1.6955 | |
| HCC1143 | TNBC | Basal A | MG-132 | Proteasome | Proteasome | 66.7 | uM | 14203.189 | 0.9180 | 0.9016 | 1.6955 | |
| HCC1143 | TNBC | Basal A | MG-132 | Proteasome | Proteasome | 66.7 | uM | 14203.189 | 0.9180 | 0.9016 | 1.6955 | |
| HCC1187 | TNBC | Basal A | MG-132 | Proteasome | Proteasome | 0.000171 | uM | 10753.145 | 0.9772 | 0.9699 | 1.5180 | |
| HCC1187 | TNBC | Basal A | MG-132 | Proteasome | Proteasome | 0.000171 | uM | 10753.145 | 0.9772 | 0.9699 | 1.5180 | |
| HCC1187 | TNBC | Basal A | MG-132 | Proteasome | Proteasome | 0.000853 | uM | 10753.145 | 0.9118 | 0.8820 | 1.5180 | |
| HCC1187 | TNBC | Basal A | MG-132 | Proteasome | Proteasome | 0.000853 | uM | 10753.145 | 0.9118 | 0.8820 | 1.5180 | |
| HCC1187 | TNBC | Basal A | MG-132 | Proteasome | Proteasome | 0.00427 | uM | 10753.145 | 0.9449 | 0.9267 | 1.5180 | |
| HCC1187 | TNBC | Basal A | MG-132 | Proteasome | Proteasome | 0.00427 | uM | 10753.145 | 0.9449 | 0.9267 | 1.5180 | |
| HCC1187 | TNBC | Basal A | MG-132 | Proteasome | Proteasome | 0.0213 | uM | 10753.145 | 0.8876 | 0.8489 | 1.5180 | |
| HCC1187 | TNBC | Basal A | MG-132 | Proteasome | Proteasome | 0.0213 | uM | 10753.145 | 0.8876 | 0.8489 | 1.5180 | |
| HCC1187 | TNBC | Basal A | MG-132 | Proteasome | Proteasome | 0.107 | uM | 10753.145 | 0.5804 | 0.3976 | 1.5180 | |
| HCC1187 | TNBC | Basal A | MG-132 | Proteasome | Proteasome | 0.107 | uM | 10753.145 | 0.5804 | 0.3976 | 1.5180 | |
| HCC1187 | TNBC | Basal A | MG-132 | Proteasome | Proteasome | 0.533 | uM | 10753.145 | 0.0206 | -0.8450 | 1.5180 | |
| HCC1187 | TNBC | Basal A | MG-132 | Proteasome | Proteasome | 0.533 | uM | 10753.145 | 0.0206 | -0.8450 | 1.5180 | |
| HCC1187 | TNBC | Basal A | MG-132 | Proteasome | Proteasome | 2.67 | uM | 10753.145 | 0.0140 | -0.8799 | 1.5180 | |
| HCC1187 | TNBC | Basal A | MG-132 | Proteasome | Proteasome | 2.67 | uM | 10753.145 | 0.0140 | -0.8799 | 1.5180 | |
| HCC1187 | TNBC | Basal A | MG-132 | Proteasome | Proteasome | 13.3 | uM | 10753.145 | 0.0168 | -0.8645 | 1.5180 | |
| HCC1187 | TNBC | Basal A | MG-132 | Proteasome | Proteasome | 13.3 | uM | 10753.145 | 0.0168 | -0.8645 | 1.5180 | |
| HCC1187 | TNBC | Basal A | MG-132 | Proteasome | Proteasome | 66.7 | uM | 10753.145 | 0.0064 | -0.9286 | 1.5180 | |
| HCC1187 | TNBC | Basal A | MG-132 | Proteasome | Proteasome | 66.7 | uM | 10753.145 | 0.0064 | -0.9286 | 1.5180 | |
| HCC1395 | TNBC | Basal B | MG-132 | Proteasome | Proteasome | 0.000171 | uM | 12000.145 | 1.0108 | 1.0357 | 0.6084 | |
| HCC1395 | TNBC | Basal B | MG-132 | Proteasome | Proteasome | 0.000171 | uM | 12000.145 | 1.0108 | 1.0357 | 0.6084 | |
| HCC1395 | TNBC | Basal B | MG-132 | Proteasome | Proteasome | 0.000853 | uM | 12000.145 | 0.9579 | 0.8634 | 0.6084 |