Growth rate-corrected (GR) dose-response metrics across a panel of 71 breast cancer cell lines treated with a library of small molecule and antibody perturbagens. Dataset 1 of 4: Relative cell counts and normalized growth rate inhibition values across technical replicates. - Dataset (ID:20268)
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| Cell | Clinical Subtype | Transcriptional Subtype | Small Molecule | Antibody | Perturbagen Target | Perturbagen Class | Perturbagen Concentration | Perturbagen Conc Unit | Biological Replicate ID | Relative Cell Count | Normalized Growth Rate Inhibition Value | Nominal Division Rate |
|---|---|---|---|---|---|---|---|---|---|---|---|---|
| BT-474 | HER2amp | Luminal | MG-132 | Proteasome | Proteasome | 66.7 | uM | 12178.145 | 0.1347 | -0.9242 | 0.6127 | |
| BT-474 | HER2amp | Luminal | MG-132 | Proteasome | Proteasome | 66.7 | uM | 12178.145 | 0.1347 | -0.9242 | 0.6127 | |
| BT-474 | HER2amp | Luminal | MG-132 | Proteasome | Proteasome | 0.000171 | uM | 12291.17 | 0.8595 | 0.5250 | 0.5585 | |
| BT-474 | HER2amp | Luminal | MG-132 | Proteasome | Proteasome | 0.000171 | uM | 12291.17 | 0.8595 | 0.5250 | 0.5585 | |
| BT-474 | HER2amp | Luminal | MG-132 | Proteasome | Proteasome | 0.000853 | uM | 12291.17 | 0.8528 | 0.5040 | 0.5585 | |
| BT-474 | HER2amp | Luminal | MG-132 | Proteasome | Proteasome | 0.000853 | uM | 12291.17 | 0.8528 | 0.5040 | 0.5585 | |
| BT-474 | HER2amp | Luminal | MG-132 | Proteasome | Proteasome | 0.00427 | uM | 12291.17 | 0.9439 | 0.8036 | 0.5585 | |
| BT-474 | HER2amp | Luminal | MG-132 | Proteasome | Proteasome | 0.00427 | uM | 12291.17 | 0.9439 | 0.8036 | 0.5585 | |
| BT-474 | HER2amp | Luminal | MG-132 | Proteasome | Proteasome | 0.0213 | uM | 12291.17 | 0.9151 | 0.7063 | 0.5585 | |
| BT-474 | HER2amp | Luminal | MG-132 | Proteasome | Proteasome | 0.0213 | uM | 12291.17 | 0.9151 | 0.7063 | 0.5585 | |
| BT-474 | HER2amp | Luminal | MG-132 | Proteasome | Proteasome | 0.107 | uM | 12291.17 | 0.9068 | 0.6787 | 0.5585 | |
| BT-474 | HER2amp | Luminal | MG-132 | Proteasome | Proteasome | 0.107 | uM | 12291.17 | 0.9068 | 0.6787 | 0.5585 | |
| BT-474 | HER2amp | Luminal | MG-132 | Proteasome | Proteasome | 0.533 | uM | 12291.17 | 0.4858 | -0.4508 | 0.5585 | |
| BT-474 | HER2amp | Luminal | MG-132 | Proteasome | Proteasome | 0.533 | uM | 12291.17 | 0.4858 | -0.4508 | 0.5585 | |
| BT-474 | HER2amp | Luminal | MG-132 | Proteasome | Proteasome | 2.67 | uM | 12291.17 | 0.2372 | -0.8479 | 0.5585 | |
| BT-474 | HER2amp | Luminal | MG-132 | Proteasome | Proteasome | 2.67 | uM | 12291.17 | 0.2372 | -0.8479 | 0.5585 | |
| BT-474 | HER2amp | Luminal | MG-132 | Proteasome | Proteasome | 13.3 | uM | 12291.17 | 0.1238 | -0.9525 | 0.5585 | |
| BT-474 | HER2amp | Luminal | MG-132 | Proteasome | Proteasome | 13.3 | uM | 12291.17 | 0.1238 | -0.9525 | 0.5585 | |
| BT-474 | HER2amp | Luminal | MG-132 | Proteasome | Proteasome | 66.7 | uM | 12291.17 | 0.0958 | -0.9700 | 0.5585 | |
| BT-474 | HER2amp | Luminal | MG-132 | Proteasome | Proteasome | 66.7 | uM | 12291.17 | 0.0958 | -0.9700 | 0.5585 | |
| BT-474 | HER2amp | Luminal | MG-132 | Proteasome | Proteasome | 0.000171 | uM | 14119.189 | 0.9940 | 0.9902 | 1.2143 | |
| BT-474 | HER2amp | Luminal | MG-132 | Proteasome | Proteasome | 0.000171 | uM | 14119.189 | 0.9940 | 0.9902 | 1.2143 | |
| BT-474 | HER2amp | Luminal | MG-132 | Proteasome | Proteasome | 0.000853 | uM | 14119.189 | 0.8645 | 0.7740 | 1.2143 | |
| BT-474 | HER2amp | Luminal | MG-132 | Proteasome | Proteasome | 0.000853 | uM | 14119.189 | 0.8645 | 0.7740 | 1.2143 | |
| BT-474 | HER2amp | Luminal | MG-132 | Proteasome | Proteasome | 0.00427 | uM | 14119.189 | 0.9826 | 0.9713 | 1.2143 |