Growth rate-corrected (GR) dose-response metrics across a panel of 71 breast cancer cell lines treated with a library of small molecule and antibody perturbagens. Dataset 1 of 4: Relative cell counts and normalized growth rate inhibition values across technical replicates. - Dataset (ID:20268)
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| Cell | Clinical Subtype | Transcriptional Subtype | Small Molecule | Antibody | Perturbagen Target | Perturbagen Class | Perturbagen Concentration | Perturbagen Conc Unit | Biological Replicate ID | Relative Cell Count | Normalized Growth Rate Inhibition Value | Nominal Division Rate |
|---|---|---|---|---|---|---|---|---|---|---|---|---|
| CAMA-1 | HR+ | Luminal | AG1024 | IGF1R | RTK | 6.67 | uM | 5911.066 | 0.9003 | 0.8378 | 1.2414 | |
| CAMA-1 | HR+ | Luminal | AG1024 | IGF1R | RTK | 33.3 | uM | 5911.066 | 0.5454 | 0.2273 | 1.2414 | |
| CAMA-1 | HR+ | Luminal | AG1024 | IGF1R | RTK | 0.0000853 | uM | 5912.066 | 0.9988 | 0.9978 | 1.0480 | |
| CAMA-1 | HR+ | Luminal | AG1024 | IGF1R | RTK | 0.000427 | uM | 5912.066 | 0.9941 | 0.9888 | 1.0480 | |
| CAMA-1 | HR+ | Luminal | AG1024 | IGF1R | RTK | 0.00213 | uM | 5912.066 | 1.0384 | 1.0732 | 1.0480 | |
| CAMA-1 | HR+ | Luminal | AG1024 | IGF1R | RTK | 0.0107 | uM | 5912.066 | 0.9603 | 0.9242 | 1.0480 | |
| CAMA-1 | HR+ | Luminal | AG1024 | IGF1R | RTK | 0.0533 | uM | 5912.066 | 0.9731 | 0.9485 | 1.0480 | |
| CAMA-1 | HR+ | Luminal | AG1024 | IGF1R | RTK | 0.267 | uM | 5912.066 | 1.0278 | 1.0530 | 1.0480 | |
| CAMA-1 | HR+ | Luminal | AG1024 | IGF1R | RTK | 1.33 | uM | 5912.066 | 1.0276 | 1.0526 | 1.0480 | |
| CAMA-1 | HR+ | Luminal | AG1024 | IGF1R | RTK | 6.67 | uM | 5912.066 | 0.9432 | 0.8914 | 1.0480 | |
| CAMA-1 | HR+ | Luminal | AG1024 | IGF1R | RTK | 33.3 | uM | 5912.066 | 0.8396 | 0.6927 | 1.0480 | |
| HBL-100 | Unknown | Unknown | AG1024 | IGF1R | RTK | 0.0000853 | uM | 7429.066 | 0.9782 | 0.9817 | 2.3904 | |
| HBL-100 | Unknown | Unknown | AG1024 | IGF1R | RTK | 0.000427 | uM | 7429.066 | 0.9946 | 0.9954 | 2.3904 | |
| HBL-100 | Unknown | Unknown | AG1024 | IGF1R | RTK | 0.00213 | uM | 7429.066 | 1.0375 | 1.0310 | 2.3904 | |
| HBL-100 | Unknown | Unknown | AG1024 | IGF1R | RTK | 0.0107 | uM | 7429.066 | 1.0032 | 1.0027 | 2.3904 | |
| HBL-100 | Unknown | Unknown | AG1024 | IGF1R | RTK | 0.0533 | uM | 7429.066 | 0.9736 | 0.9778 | 2.3904 | |
| HBL-100 | Unknown | Unknown | AG1024 | IGF1R | RTK | 0.267 | uM | 7429.066 | 0.9585 | 0.9648 | 2.3904 | |
| HBL-100 | Unknown | Unknown | AG1024 | IGF1R | RTK | 1.33 | uM | 7429.066 | 0.9746 | 0.9786 | 2.3904 | |
| HBL-100 | Unknown | Unknown | AG1024 | IGF1R | RTK | 6.67 | uM | 7429.066 | 0.9903 | 0.9919 | 2.3904 | |
| HBL-100 | Unknown | Unknown | AG1024 | IGF1R | RTK | 33.3 | uM | 7429.066 | 1.0079 | 1.0066 | 2.3904 | |
| HCC1143 | TNBC | Basal A | AG1024 | IGF1R | RTK | 0.0000853 | uM | 7430.066 | 0.9778 | 0.9747 | 1.7623 | |
| HCC1143 | TNBC | Basal A | AG1024 | IGF1R | RTK | 0.000427 | uM | 7430.066 | 1.0569 | 1.0638 | 1.7623 | |
| HCC1143 | TNBC | Basal A | AG1024 | IGF1R | RTK | 0.00213 | uM | 7430.066 | 0.9932 | 0.9922 | 1.7623 | |
| HCC1143 | TNBC | Basal A | AG1024 | IGF1R | RTK | 0.0107 | uM | 7430.066 | 0.9999 | 0.9999 | 1.7623 | |
| HCC1143 | TNBC | Basal A | AG1024 | IGF1R | RTK | 0.0533 | uM | 7430.066 | 1.0752 | 1.0840 | 1.7623 |