Growth rate-corrected (GR) dose-response metrics across a panel of 71 breast cancer cell lines treated with a library of small molecule and antibody perturbagens. Dataset 1 of 4: Relative cell counts and normalized growth rate inhibition values across technical replicates. - Dataset (ID:20268)
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| Cell | Clinical Subtype | Transcriptional Subtype | Small Molecule | Antibody | Perturbagen Target | Perturbagen Class | Perturbagen Concentration | Perturbagen Conc Unit | Biological Replicate ID | Relative Cell Count | Normalized Growth Rate Inhibition Value | Nominal Division Rate |
|---|---|---|---|---|---|---|---|---|---|---|---|---|
| SUM159PT | TNBC | Basal B | Mebendazole | 2.67 | uM | 13004.174 | 0.0705 | -0.1099 | 3.2757 | |||
| SUM159PT | TNBC | Basal B | Mebendazole | 13.3 | uM | 13004.174 | 0.0561 | -0.1697 | 3.2757 | |||
| SUM159PT | TNBC | Basal B | Mebendazole | 66.7 | uM | 13004.174 | 0.0551 | -0.1743 | 3.2757 | |||
| SUM159PT | TNBC | Basal B | Mebendazole | 0.000171 | uM | 13054.174 | 0.9538 | 0.9699 | 3.1161 | |||
| SUM159PT | TNBC | Basal B | Mebendazole | 0.000853 | uM | 13054.174 | 0.9827 | 0.9889 | 3.1161 | |||
| SUM159PT | TNBC | Basal B | Mebendazole | 0.00427 | uM | 13054.174 | 0.7299 | 0.8078 | 3.1161 | |||
| SUM159PT | TNBC | Basal B | Mebendazole | 0.0213 | uM | 13054.174 | 0.8470 | 0.8962 | 3.1161 | |||
| SUM159PT | TNBC | Basal B | Mebendazole | 0.107 | uM | 13054.174 | 0.7956 | 0.8585 | 3.1161 | |||
| SUM159PT | TNBC | Basal B | Mebendazole | 0.533 | uM | 13054.174 | 0.2481 | 0.2786 | 3.1161 | |||
| SUM159PT | TNBC | Basal B | Mebendazole | 2.67 | uM | 13054.174 | 0.2354 | 0.2572 | 3.1161 | |||
| SUM159PT | TNBC | Basal B | Mebendazole | 13.3 | uM | 13054.174 | 0.2435 | 0.2710 | 3.1161 | |||
| SUM159PT | TNBC | Basal B | Mebendazole | 66.7 | uM | 13054.174 | 0.1435 | 0.0726 | 3.1161 | |||
| SUM185PE | TNBC | Luminal | Mebendazole | 0.000171 | uM | 13140.174 | 0.9887 | 0.9609 | 0.5769 | |||
| SUM185PE | TNBC | Luminal | Mebendazole | 0.000853 | uM | 13140.174 | 0.9600 | 0.8632 | 0.5769 | |||
| SUM185PE | TNBC | Luminal | Mebendazole | 0.00427 | uM | 13140.174 | 0.9663 | 0.8845 | 0.5769 | |||
| SUM185PE | TNBC | Luminal | Mebendazole | 0.0213 | uM | 13140.174 | 0.9518 | 0.8358 | 0.5769 | |||
| SUM185PE | TNBC | Luminal | Mebendazole | 0.107 | uM | 13140.174 | 0.9821 | 0.9383 | 0.5769 | |||
| SUM185PE | TNBC | Luminal | Mebendazole | 0.533 | uM | 13140.174 | 0.7990 | 0.3556 | 0.5769 | |||
| SUM185PE | TNBC | Luminal | Mebendazole | 2.67 | uM | 13140.174 | 0.6451 | -0.0645 | 0.5769 | |||
| SUM185PE | TNBC | Luminal | Mebendazole | 13.3 | uM | 13140.174 | 0.6386 | -0.0809 | 0.5769 | |||
| SUM185PE | TNBC | Luminal | Mebendazole | 66.7 | uM | 13140.174 | 0.6894 | 0.0495 | 0.5769 | |||
| SUM229PE | TNBC | - | Mebendazole | 0.000171 | uM | 13009.174 | 0.9719 | 0.9599 | 1.4104 | |||
| SUM229PE | TNBC | - | Mebendazole | 0.000853 | uM | 13009.174 | 0.9120 | 0.8735 | 1.4104 | |||
| SUM229PE | TNBC | - | Mebendazole | 0.00427 | uM | 13009.174 | 0.9857 | 0.9797 | 1.4104 | |||
| SUM229PE | TNBC | - | Mebendazole | 0.0213 | uM | 13009.174 | 0.9345 | 0.9062 | 1.4104 |