Growth rate-corrected (GR) dose-response metrics across a panel of 71 breast cancer cell lines treated with a library of small molecule and antibody perturbagens. Dataset 1 of 4: Relative cell counts and normalized growth rate inhibition values across technical replicates. - Dataset (ID:20268)
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| Cell | Clinical Subtype | Transcriptional Subtype | Small Molecule | Antibody | Perturbagen Target | Perturbagen Class | Perturbagen Concentration | Perturbagen Conc Unit | Biological Replicate ID | Relative Cell Count | Normalized Growth Rate Inhibition Value | Nominal Division Rate |
|---|---|---|---|---|---|---|---|---|---|---|---|---|
| MDA-MB-134-VI | HR+ | Luminal | Ixabepilone | TUBB | TUBB | 0.0126 | uM | 10419.095 | 0.4254 | -0.3597 | 0.7505 | |
| MDA-MB-134-VI | HR+ | Luminal | Ixabepilone | TUBB | TUBB | 0.0631 | uM | 10419.095 | 0.3660 | -0.4759 | 0.7505 | |
| MDA-MB-134-VI | HR+ | Luminal | Ixabepilone | TUBB | TUBB | 0.316 | uM | 10419.095 | 0.3771 | -0.4546 | 0.7505 | |
| MDA-MB-134-VI | HR+ | Luminal | Ixabepilone | TUBB | TUBB | 1.58 | uM | 10419.095 | 0.4097 | -0.3910 | 0.7505 | |
| MDA-MB-134-VI | HR+ | Luminal | Ixabepilone | TUBB | TUBB | 7.89 | uM | 10419.095 | 0.4762 | -0.2557 | 0.7505 | |
| MDA-MB-134-VI | HR+ | Luminal | Ixabepilone | TUBB | TUBB | 39.4 | uM | 10419.095 | 0.0060 | -0.9978 | 0.7505 | |
| MDA-MB-157 | TNBC | Basal B | Ixabepilone | TUBB | TUBB | 0.000101 | uM | 7496.095 | 1.0528 | 1.1020 | 1.0348 | |
| MDA-MB-157 | TNBC | Basal B | Ixabepilone | TUBB | TUBB | 0.000505 | uM | 7496.095 | 1.0270 | 1.0521 | 1.0348 | |
| MDA-MB-157 | TNBC | Basal B | Ixabepilone | TUBB | TUBB | 0.00252 | uM | 7496.095 | 0.9460 | 0.8955 | 1.0348 | |
| MDA-MB-157 | TNBC | Basal B | Ixabepilone | TUBB | TUBB | 0.0126 | uM | 7496.095 | 0.5305 | 0.0840 | 1.0348 | |
| MDA-MB-157 | TNBC | Basal B | Ixabepilone | TUBB | TUBB | 0.0631 | uM | 7496.095 | 0.2559 | -0.4641 | 1.0348 | |
| MDA-MB-157 | TNBC | Basal B | Ixabepilone | TUBB | TUBB | 0.316 | uM | 7496.095 | 0.1577 | -0.6644 | 1.0348 | |
| MDA-MB-157 | TNBC | Basal B | Ixabepilone | TUBB | TUBB | 1.58 | uM | 7496.095 | 0.1230 | -0.7360 | 1.0348 | |
| MDA-MB-157 | TNBC | Basal B | Ixabepilone | TUBB | TUBB | 7.89 | uM | 7496.095 | 0.1090 | -0.7652 | 1.0348 | |
| MDA-MB-157 | TNBC | Basal B | Ixabepilone | TUBB | TUBB | 39.4 | uM | 7496.095 | 0.0018 | -0.9956 | 1.0348 | |
| MDA-MB-157 | TNBC | Basal B | Ixabepilone | TUBB | TUBB | 0.000101 | uM | 7498.095 | 0.9840 | 0.9739 | 1.2329 | |
| MDA-MB-157 | TNBC | Basal B | Ixabepilone | TUBB | TUBB | 0.000505 | uM | 7498.095 | 0.9139 | 0.8592 | 1.2329 | |
| MDA-MB-157 | TNBC | Basal B | Ixabepilone | TUBB | TUBB | 0.00252 | uM | 7498.095 | 0.7865 | 0.6461 | 1.2329 | |
| MDA-MB-157 | TNBC | Basal B | Ixabepilone | TUBB | TUBB | 0.0126 | uM | 7498.095 | 0.3324 | -0.1814 | 1.2329 | |
| MDA-MB-157 | TNBC | Basal B | Ixabepilone | TUBB | TUBB | 0.0631 | uM | 7498.095 | 0.2744 | -0.2994 | 1.2329 | |
| MDA-MB-157 | TNBC | Basal B | Ixabepilone | TUBB | TUBB | 0.316 | uM | 7498.095 | 0.2155 | -0.4240 | 1.2329 | |
| MDA-MB-157 | TNBC | Basal B | Ixabepilone | TUBB | TUBB | 1.58 | uM | 7498.095 | 0.1621 | -0.5428 | 1.2329 | |
| MDA-MB-157 | TNBC | Basal B | Ixabepilone | TUBB | TUBB | 7.89 | uM | 7498.095 | 0.1656 | -0.5347 | 1.2329 | |
| MDA-MB-157 | TNBC | Basal B | Ixabepilone | TUBB | TUBB | 39.4 | uM | 7498.095 | 0.0069 | -0.9649 | 1.2329 | |
| MDA-MB-175-VII | HR+ | Luminal | Ixabepilone | TUBB | TUBB | 0.000505 | uM | 7499.094 | 0.9295 | 0.7843 | 0.6407 |