Growth rate-corrected (GR) dose-response metrics across a panel of 71 breast cancer cell lines treated with a library of small molecule and antibody perturbagens. Dataset 1 of 4: Relative cell counts and normalized growth rate inhibition values across technical replicates. - Dataset (ID:20268)
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| Cell | Clinical Subtype | Transcriptional Subtype | Small Molecule | Antibody | Perturbagen Target | Perturbagen Class | Perturbagen Concentration | Perturbagen Conc Unit | Biological Replicate ID | Relative Cell Count | Normalized Growth Rate Inhibition Value | Nominal Division Rate |
|---|---|---|---|---|---|---|---|---|---|---|---|---|
| MDA-MB-453 | TNBC | Luminal | 5-FU | TYMS | TYMS | 769 | uM | 9708.017 | 0.5818 | 0.2195 | 1.0949 | |
| MDA-MB-453 | TNBC | Luminal | 5-FU | TYMS | TYMS | 3840 | uM | 9708.017 | 0.3748 | -0.1839 | 1.0949 | |
| MDA-MB-453 | TNBC | Luminal | 5-FU | TYMS | TYMS | 19200 | uM | 9708.017 | 0.2486 | -0.4391 | 1.0949 | |
| MDA-MB-468 | TNBC | Basal A | 5-FU | TYMS | TYMS | 0.0492 | uM | 7904.017 | 0.9420 | 0.9165 | 1.4023 | |
| MDA-MB-468 | TNBC | Basal A | 5-FU | TYMS | TYMS | 0.246 | uM | 7904.017 | 1.2187 | 1.3029 | 1.4023 | |
| MDA-MB-468 | TNBC | Basal A | 5-FU | TYMS | TYMS | 1.23 | uM | 7904.017 | 0.9160 | 0.8786 | 1.4023 | |
| MDA-MB-468 | TNBC | Basal A | 5-FU | TYMS | TYMS | 6.15 | uM | 7904.017 | 1.1758 | 1.2448 | 1.4023 | |
| MDA-MB-468 | TNBC | Basal A | 5-FU | TYMS | TYMS | 30.7 | uM | 7904.017 | 0.9373 | 0.9097 | 1.4023 | |
| MDA-MB-468 | TNBC | Basal A | 5-FU | TYMS | TYMS | 154 | uM | 7904.017 | 0.6833 | 0.5244 | 1.4023 | |
| MDA-MB-468 | TNBC | Basal A | 5-FU | TYMS | TYMS | 769 | uM | 7904.017 | 0.4387 | 0.1114 | 1.4023 | |
| MDA-MB-468 | TNBC | Basal A | 5-FU | TYMS | TYMS | 3840 | uM | 7904.017 | 0.2741 | -0.2053 | 1.4023 | |
| MDA-MB-468 | TNBC | Basal A | 5-FU | TYMS | TYMS | 19200 | uM | 7904.017 | 0.2629 | -0.2286 | 1.4023 | |
| MDA-MB-468 | TNBC | Basal A | 5-FU | TYMS | TYMS | 0.0492 | uM | 7905.035 | 0.8584 | 0.6742 | 0.8588 | |
| MDA-MB-468 | TNBC | Basal A | 5-FU | TYMS | TYMS | 0.246 | uM | 7905.035 | 0.9507 | 0.8858 | 0.8588 | |
| MDA-MB-468 | TNBC | Basal A | 5-FU | TYMS | TYMS | 1.23 | uM | 7905.035 | 0.8446 | 0.6430 | 0.8588 | |
| MDA-MB-468 | TNBC | Basal A | 5-FU | TYMS | TYMS | 6.15 | uM | 7905.035 | 1.1260 | 1.2963 | 0.8588 | |
| MDA-MB-468 | TNBC | Basal A | 5-FU | TYMS | TYMS | 30.7 | uM | 7905.035 | 0.9097 | 0.7913 | 0.8588 | |
| MDA-MB-468 | TNBC | Basal A | 5-FU | TYMS | TYMS | 154 | uM | 7905.035 | 0.6713 | 0.2574 | 0.8588 | |
| MDA-MB-468 | TNBC | Basal A | 5-FU | TYMS | TYMS | 769 | uM | 7905.035 | 0.3591 | -0.3932 | 0.8588 | |
| MDA-MB-468 | TNBC | Basal A | 5-FU | TYMS | TYMS | 3840 | uM | 7905.035 | 0.1871 | -0.7160 | 0.8588 | |
| MDA-MB-468 | TNBC | Basal A | 5-FU | TYMS | TYMS | 19200 | uM | 7905.035 | 0.1152 | -0.8385 | 0.8588 | |
| MDA-MB-468 | TNBC | Basal A | 5-FU | TYMS | TYMS | 0.0492 | uM | 7906.017 | 1.1139 | 1.6523 | 0.3822 | |
| MDA-MB-468 | TNBC | Basal A | 5-FU | TYMS | TYMS | 0.246 | uM | 7906.017 | 1.1834 | 2.1074 | 0.3822 | |
| MDA-MB-468 | TNBC | Basal A | 5-FU | TYMS | TYMS | 1.23 | uM | 7906.017 | 1.0495 | 1.2695 | 0.3822 | |
| MDA-MB-468 | TNBC | Basal A | 5-FU | TYMS | TYMS | 6.15 | uM | 7906.017 | 0.9819 | 0.9065 | 0.3822 |