Growth rate-corrected (GR) dose-response metrics across a panel of 71 breast cancer cell lines treated with a library of small molecule and antibody perturbagens. Dataset 1 of 4: Relative cell counts and normalized growth rate inhibition values across technical replicates. - Dataset (ID:20268)
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| Cell | Clinical Subtype | Transcriptional Subtype | Small Molecule | Antibody | Perturbagen Target | Perturbagen Class | Perturbagen Concentration | Perturbagen Conc Unit | Biological Replicate ID | Relative Cell Count | Normalized Growth Rate Inhibition Value | Nominal Division Rate |
|---|---|---|---|---|---|---|---|---|---|---|---|---|
| MCF 10F | NM | - | GSK461364 | PLK1 | PLK | 0.000427 | uM | 7871.001 | 1.0754 | 1.1462 | 1.0311 | |
| MCF 10F | NM | - | GSK461364 | PLK1 | PLK | 0.00213 | uM | 7871.001 | 1.0245 | 1.0474 | 1.0311 | |
| MCF 10F | NM | - | GSK461364 | PLK1 | PLK | 0.0107 | uM | 7871.001 | 0.6453 | 0.3078 | 1.0311 | |
| MCF 10F | NM | - | GSK461364 | PLK1 | PLK | 0.0533 | uM | 7871.001 | 0.5705 | 0.1606 | 1.0311 | |
| MCF 10F | NM | - | GSK461364 | PLK1 | PLK | 0.267 | uM | 7871.001 | 0.4507 | -0.0766 | 1.0311 | |
| MCF 10F | NM | - | GSK461364 | PLK1 | PLK | 1.33 | uM | 7871.001 | 0.5176 | 0.0560 | 1.0311 | |
| MCF 10F | NM | - | GSK461364 | PLK1 | PLK | 6.67 | uM | 7871.001 | 0.5342 | 0.0887 | 1.0311 | |
| MCF 10F | NM | - | GSK461364 | PLK1 | PLK | 33.3 | uM | 7871.001 | 0.3194 | -0.3389 | 1.0311 | |
| MCF 10F | NM | - | GSK461364 | PLK1 | PLK | 0.0000853 | uM | 7872.001 | 1.0201 | 1.0295 | 1.3610 | |
| MCF 10F | NM | - | GSK461364 | PLK1 | PLK | 0.000427 | uM | 7872.001 | 1.0970 | 1.1408 | 1.3610 | |
| MCF 10F | NM | - | GSK461364 | PLK1 | PLK | 0.00213 | uM | 7872.001 | 0.9062 | 0.8604 | 1.3610 | |
| MCF 10F | NM | - | GSK461364 | PLK1 | PLK | 0.0107 | uM | 7872.001 | 0.7313 | 0.5892 | 1.3610 | |
| MCF 10F | NM | - | GSK461364 | PLK1 | PLK | 0.0533 | uM | 7872.001 | 0.5841 | 0.3472 | 1.3610 | |
| MCF 10F | NM | - | GSK461364 | PLK1 | PLK | 0.267 | uM | 7872.001 | 0.4974 | 0.1972 | 1.3610 | |
| MCF 10F | NM | - | GSK461364 | PLK1 | PLK | 1.33 | uM | 7872.001 | 0.6274 | 0.4199 | 1.3610 | |
| MCF 10F | NM | - | GSK461364 | PLK1 | PLK | 6.67 | uM | 7872.001 | 0.5387 | 0.2696 | 1.3610 | |
| MCF 10F | NM | - | GSK461364 | PLK1 | PLK | 33.3 | uM | 7872.001 | 0.0328 | -0.8377 | 1.3610 | |
| MCF 10F | NM | - | GSK461364 | PLK1 | PLK | 0.0000853 | uM | 9566.001 | 0.9898 | 0.9903 | 2.1122 | |
| MCF 10F | NM | - | GSK461364 | PLK1 | PLK | 0.000427 | uM | 9566.001 | 1.0753 | 1.0699 | 2.1122 | |
| MCF 10F | NM | - | GSK461364 | PLK1 | PLK | 0.00213 | uM | 9566.001 | 1.0151 | 1.0143 | 2.1122 | |
| MCF 10F | NM | - | GSK461364 | PLK1 | PLK | 0.0107 | uM | 9566.001 | 0.9772 | 0.9783 | 2.1122 | |
| MCF 10F | NM | - | GSK461364 | PLK1 | PLK | 0.0533 | uM | 9566.001 | 0.6688 | 0.6531 | 2.1122 | |
| MCF 10F | NM | - | GSK461364 | PLK1 | PLK | 0.267 | uM | 9566.001 | 0.4777 | 0.4097 | 2.1122 | |
| MCF 10F | NM | - | GSK461364 | PLK1 | PLK | 1.33 | uM | 9566.001 | 0.4875 | 0.4233 | 2.1122 | |
| MCF 10F | NM | - | GSK461364 | PLK1 | PLK | 6.67 | uM | 9566.001 | 0.5496 | 0.5065 | 2.1122 |