Growth rate-corrected (GR) dose-response metrics across a panel of 71 breast cancer cell lines treated with a library of small molecule and antibody perturbagens. Dataset 1 of 4: Relative cell counts and normalized growth rate inhibition values across technical replicates. - Dataset (ID:20268)
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| Cell | Clinical Subtype | Transcriptional Subtype | Small Molecule | Antibody | Perturbagen Target | Perturbagen Class | Perturbagen Concentration | Perturbagen Conc Unit | Biological Replicate ID | Relative Cell Count | Normalized Growth Rate Inhibition Value | Nominal Division Rate |
|---|---|---|---|---|---|---|---|---|---|---|---|---|
| Hs 578T | TNBC | Basal B | GSK1838705A | IGF1R | RTK | 0.00154 | uM | 7473.071 | 1.1862 | 1.1453 | 2.4352 | |
| Hs 578T | TNBC | Basal B | GSK1838705A | IGF1R | RTK | 0.00768 | uM | 7473.071 | 1.2006 | 1.1559 | 2.4352 | |
| Hs 578T | TNBC | Basal B | GSK1838705A | IGF1R | RTK | 0.0384 | uM | 7473.071 | 1.1274 | 1.1009 | 2.4352 | |
| Hs 578T | TNBC | Basal B | GSK1838705A | IGF1R | RTK | 0.192 | uM | 7473.071 | 1.0654 | 1.0527 | 2.4352 | |
| Hs 578T | TNBC | Basal B | GSK1838705A | IGF1R | RTK | 0.96 | uM | 7473.071 | 1.6861 | 1.4785 | 2.4352 | |
| Hs 578T | TNBC | Basal B | GSK1838705A | IGF1R | RTK | 4.8 | uM | 7473.071 | 1.9441 | 1.6278 | 2.4352 | |
| Hs 578T | TNBC | Basal B | GSK1838705A | IGF1R | RTK | 24 | uM | 7473.071 | 0.2026 | 0.0382 | 2.4352 | |
| Hs 578T | TNBC | Basal B | GSK1838705A | IGF1R | RTK | 120 | uM | 7473.071 | 0.1487 | -0.0857 | 2.4352 | |
| Hs 578T | TNBC | Basal B | GSK1838705A | IGF1R | RTK | 0.000341 | uM | 7473.091 | 1.3527 | 1.2769 | 2.3297 | |
| Hs 578T | TNBC | Basal B | GSK1838705A | IGF1R | RTK | 0.00171 | uM | 7473.091 | 1.3335 | 1.2630 | 2.3297 | |
| Hs 578T | TNBC | Basal B | GSK1838705A | IGF1R | RTK | 0.00853 | uM | 7473.091 | 1.2923 | 1.2327 | 2.3297 | |
| Hs 578T | TNBC | Basal B | GSK1838705A | IGF1R | RTK | 0.0427 | uM | 7473.091 | 1.3022 | 1.2401 | 2.3297 | |
| Hs 578T | TNBC | Basal B | GSK1838705A | IGF1R | RTK | 0.213 | uM | 7473.091 | 1.2062 | 1.1676 | 2.3297 | |
| Hs 578T | TNBC | Basal B | GSK1838705A | IGF1R | RTK | 1.07 | uM | 7473.091 | 1.3430 | 1.2699 | 2.3297 | |
| Hs 578T | TNBC | Basal B | GSK1838705A | IGF1R | RTK | 5.33 | uM | 7473.091 | 1.7198 | 1.5241 | 2.3297 | |
| Hs 578T | TNBC | Basal B | GSK1838705A | IGF1R | RTK | 26.7 | uM | 7473.091 | 2.1810 | 1.7951 | 2.3297 | |
| Hs 578T | TNBC | Basal B | GSK1838705A | IGF1R | RTK | 133 | uM | 7473.091 | 0.8892 | 0.9017 | 2.3297 | |
| Hs 578T | TNBC | Basal B | GSK1838705A | IGF1R | RTK | 0.000171 | uM | 7473.098 | 1.1330 | 1.1126 | 2.2810 | |
| Hs 578T | TNBC | Basal B | GSK1838705A | IGF1R | RTK | 0.000853 | uM | 7473.098 | 1.0867 | 1.0743 | 2.2810 | |
| Hs 578T | TNBC | Basal B | GSK1838705A | IGF1R | RTK | 0.00427 | uM | 7473.098 | 1.1739 | 1.1457 | 2.2810 | |
| Hs 578T | TNBC | Basal B | GSK1838705A | IGF1R | RTK | 0.0213 | uM | 7473.098 | 1.2270 | 1.1876 | 2.2810 | |
| Hs 578T | TNBC | Basal B | GSK1838705A | IGF1R | RTK | 0.107 | uM | 7473.098 | 1.0583 | 1.0503 | 2.2810 | |
| Hs 578T | TNBC | Basal B | GSK1838705A | IGF1R | RTK | 0.533 | uM | 7473.098 | 1.3726 | 1.2979 | 2.2810 | |
| Hs 578T | TNBC | Basal B | GSK1838705A | IGF1R | RTK | 2.67 | uM | 7473.098 | 2.2037 | 1.8280 | 2.2810 | |
| Hs 578T | TNBC | Basal B | GSK1838705A | IGF1R | RTK | 13.3 | uM | 7473.098 | 0.7272 | 0.7393 | 2.2810 |