Growth rate-corrected (GR) dose-response metrics across a panel of 71 breast cancer cell lines treated with a library of small molecule and antibody perturbagens. Dataset 1 of 4: Relative cell counts and normalized growth rate inhibition values across technical replicates. - Dataset (ID:20268)
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| Cell | Clinical Subtype | Transcriptional Subtype | Small Molecule | Antibody | Perturbagen Target | Perturbagen Class | Perturbagen Concentration | Perturbagen Conc Unit | Biological Replicate ID | Relative Cell Count | Normalized Growth Rate Inhibition Value | Nominal Division Rate |
|---|---|---|---|---|---|---|---|---|---|---|---|---|
| HCC38 | TNBC | Basal B | GSK1838705A | IGF1R | RTK | 24 | uM | 7469.071 | 0.9466 | 0.9502 | 2.1768 | |
| HCC38 | TNBC | Basal B | GSK1838705A | IGF1R | RTK | 120 | uM | 7469.071 | 0.8516 | 0.8577 | 2.1768 | |
| HCC38 | TNBC | Basal B | GSK1838705A | IGF1R | RTK | 0.000341 | uM | 7469.09 | 1.0020 | 1.0020 | 1.9867 | |
| HCC38 | TNBC | Basal B | GSK1838705A | IGF1R | RTK | 0.00171 | uM | 7469.09 | 1.0014 | 1.0014 | 1.9867 | |
| HCC38 | TNBC | Basal B | GSK1838705A | IGF1R | RTK | 0.00853 | uM | 7469.09 | 1.0280 | 1.0280 | 1.9867 | |
| HCC38 | TNBC | Basal B | GSK1838705A | IGF1R | RTK | 0.0427 | uM | 7469.09 | 1.0373 | 1.0372 | 1.9867 | |
| HCC38 | TNBC | Basal B | GSK1838705A | IGF1R | RTK | 0.213 | uM | 7469.09 | 0.9755 | 0.9752 | 1.9867 | |
| HCC38 | TNBC | Basal B | GSK1838705A | IGF1R | RTK | 1.07 | uM | 7469.09 | 0.9404 | 0.9391 | 1.9867 | |
| HCC38 | TNBC | Basal B | GSK1838705A | IGF1R | RTK | 5.33 | uM | 7469.09 | 0.9127 | 0.9101 | 1.9867 | |
| HCC38 | TNBC | Basal B | GSK1838705A | IGF1R | RTK | 26.7 | uM | 7469.09 | 0.8377 | 0.8294 | 1.9867 | |
| HCC38 | TNBC | Basal B | GSK1838705A | IGF1R | RTK | 133 | uM | 7469.09 | 0.9229 | 0.9208 | 1.9867 | |
| HCC38 | TNBC | Basal B | GSK1838705A | IGF1R | RTK | 0.000171 | uM | 7469.098 | 1.0022 | 1.0022 | 2.0111 | |
| HCC38 | TNBC | Basal B | GSK1838705A | IGF1R | RTK | 0.000853 | uM | 7469.098 | 0.9659 | 0.9657 | 2.0111 | |
| HCC38 | TNBC | Basal B | GSK1838705A | IGF1R | RTK | 0.00427 | uM | 7469.098 | 0.9597 | 0.9595 | 2.0111 | |
| HCC38 | TNBC | Basal B | GSK1838705A | IGF1R | RTK | 0.0213 | uM | 7469.098 | 0.9246 | 0.9235 | 2.0111 | |
| HCC38 | TNBC | Basal B | GSK1838705A | IGF1R | RTK | 0.107 | uM | 7469.098 | 0.9564 | 0.9562 | 2.0111 | |
| HCC38 | TNBC | Basal B | GSK1838705A | IGF1R | RTK | 0.533 | uM | 7469.098 | 0.9858 | 0.9858 | 2.0111 | |
| HCC38 | TNBC | Basal B | GSK1838705A | IGF1R | RTK | 2.67 | uM | 7469.098 | 0.9678 | 0.9678 | 2.0111 | |
| HCC38 | TNBC | Basal B | GSK1838705A | IGF1R | RTK | 13.3 | uM | 7469.098 | 0.2577 | 0.0191 | 2.0111 | |
| HCC38 | TNBC | Basal B | GSK1838705A | IGF1R | RTK | 66.7 | uM | 7469.098 | 0.0101 | -0.7962 | 2.0111 | |
| HCC70 | TNBC | Basal A | GSK1838705A | IGF1R | RTK | 0.000341 | uM | 7470.091 | 1.0027 | 1.0055 | 0.9773 | |
| HCC70 | TNBC | Basal A | GSK1838705A | IGF1R | RTK | 0.00171 | uM | 7470.091 | 1.0330 | 1.0675 | 0.9773 | |
| HCC70 | TNBC | Basal A | GSK1838705A | IGF1R | RTK | 0.00853 | uM | 7470.091 | 0.9440 | 0.8855 | 0.9773 | |
| HCC70 | TNBC | Basal A | GSK1838705A | IGF1R | RTK | 0.0427 | uM | 7470.091 | 1.0123 | 1.0251 | 0.9773 | |
| HCC70 | TNBC | Basal A | GSK1838705A | IGF1R | RTK | 0.213 | uM | 7470.091 | 1.0311 | 1.0636 | 0.9773 |