Growth rate-corrected (GR) dose-response metrics across a panel of 71 breast cancer cell lines treated with a library of small molecule and antibody perturbagens. Dataset 1 of 4: Relative cell counts and normalized growth rate inhibition values across technical replicates. - Dataset (ID:20268)
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| Cell | Clinical Subtype | Transcriptional Subtype | Small Molecule | Antibody | Perturbagen Target | Perturbagen Class | Perturbagen Concentration | Perturbagen Conc Unit | Biological Replicate ID | Relative Cell Count | Normalized Growth Rate Inhibition Value | Nominal Division Rate |
|---|---|---|---|---|---|---|---|---|---|---|---|---|
| HCC1954 | HER2amp | Basal A | GSK1838705A | IGF1R | RTK | 13.3 | uM | 7454.098 | 0.6051 | 0.3575 | 1.2964 | |
| HCC1954 | HER2amp | Basal A | GSK1838705A | IGF1R | RTK | 66.7 | uM | 7454.098 | 0.0275 | -0.8748 | 1.2964 | |
| HCC1954 | HER2amp | Basal A | GSK1838705A | IGF1R | RTK | 0.000171 | uM | 7455.092 | 1.0894 | 1.1059 | 1.6605 | |
| HCC1954 | HER2amp | Basal A | GSK1838705A | IGF1R | RTK | 0.000853 | uM | 7455.092 | 1.0617 | 1.0734 | 1.6605 | |
| HCC1954 | HER2amp | Basal A | GSK1838705A | IGF1R | RTK | 0.00427 | uM | 7455.092 | 0.9591 | 0.9504 | 1.6605 | |
| HCC1954 | HER2amp | Basal A | GSK1838705A | IGF1R | RTK | 0.0213 | uM | 7455.092 | 1.2384 | 1.2748 | 1.6605 | |
| HCC1954 | HER2amp | Basal A | GSK1838705A | IGF1R | RTK | 0.107 | uM | 7455.092 | 1.1355 | 1.1591 | 1.6605 | |
| HCC1954 | HER2amp | Basal A | GSK1838705A | IGF1R | RTK | 0.533 | uM | 7455.092 | 1.0671 | 1.0797 | 1.6605 | |
| HCC1954 | HER2amp | Basal A | GSK1838705A | IGF1R | RTK | 2.67 | uM | 7455.092 | 1.0076 | 1.0091 | 1.6605 | |
| HCC1954 | HER2amp | Basal A | GSK1838705A | IGF1R | RTK | 13.3 | uM | 7455.092 | 1.0840 | 1.0995 | 1.6605 | |
| HCC1954 | HER2amp | Basal A | GSK1838705A | IGF1R | RTK | 66.7 | uM | 7455.092 | 0.0151 | -0.8400 | 1.6605 | |
| HCC1954 | HER2amp | Basal A | GSK1838705A | IGF1R | RTK | 0.000171 | uM | 7455.098 | 1.0289 | 1.0428 | 1.3433 | |
| HCC1954 | HER2amp | Basal A | GSK1838705A | IGF1R | RTK | 0.000853 | uM | 7455.098 | 0.8992 | 0.8479 | 1.3433 | |
| HCC1954 | HER2amp | Basal A | GSK1838705A | IGF1R | RTK | 0.00427 | uM | 7455.098 | 0.9351 | 0.9025 | 1.3433 | |
| HCC1954 | HER2amp | Basal A | GSK1838705A | IGF1R | RTK | 0.0213 | uM | 7455.098 | 0.8832 | 0.8234 | 1.3433 | |
| HCC1954 | HER2amp | Basal A | GSK1838705A | IGF1R | RTK | 0.107 | uM | 7455.098 | 1.0386 | 1.0571 | 1.3433 | |
| HCC1954 | HER2amp | Basal A | GSK1838705A | IGF1R | RTK | 0.533 | uM | 7455.098 | 0.8670 | 0.7984 | 1.3433 | |
| HCC1954 | HER2amp | Basal A | GSK1838705A | IGF1R | RTK | 2.67 | uM | 7455.098 | 0.9287 | 0.8928 | 1.3433 | |
| HCC1954 | HER2amp | Basal A | GSK1838705A | IGF1R | RTK | 13.3 | uM | 7455.098 | 0.3762 | -0.0340 | 1.3433 | |
| HCC1954 | HER2amp | Basal A | GSK1838705A | IGF1R | RTK | 66.7 | uM | 7455.098 | 0.3656 | -0.0544 | 1.3433 | |
| HCC1954 | HER2amp | Basal A | GSK1838705A | IGF1R | RTK | 0.000341 | uM | 7456.091 | 0.9996 | 0.9995 | 1.7629 | |
| HCC1954 | HER2amp | Basal A | GSK1838705A | IGF1R | RTK | 0.00171 | uM | 7456.091 | 0.9435 | 0.9351 | 1.7629 | |
| HCC1954 | HER2amp | Basal A | GSK1838705A | IGF1R | RTK | 0.00853 | uM | 7456.091 | 0.9800 | 0.9772 | 1.7629 | |
| HCC1954 | HER2amp | Basal A | GSK1838705A | IGF1R | RTK | 0.0427 | uM | 7456.091 | 1.0435 | 1.0488 | 1.7629 | |
| HCC1954 | HER2amp | Basal A | GSK1838705A | IGF1R | RTK | 0.213 | uM | 7456.091 | 1.0049 | 1.0055 | 1.7629 |