Growth rate-corrected (GR) dose-response metrics across a panel of 71 breast cancer cell lines treated with a library of small molecule and antibody perturbagens. Dataset 1 of 4: Relative cell counts and normalized growth rate inhibition values across technical replicates. - Dataset (ID:20268)
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| Cell | Clinical Subtype | Transcriptional Subtype | Small Molecule | Antibody | Perturbagen Target | Perturbagen Class | Perturbagen Concentration | Perturbagen Conc Unit | Biological Replicate ID | Relative Cell Count | Normalized Growth Rate Inhibition Value | Nominal Division Rate |
|---|---|---|---|---|---|---|---|---|---|---|---|---|
| HCC1187 | TNBC | Basal A | GSK1838705A | IGF1R | RTK | 0.00768 | uM | 7433.071 | 1.0259 | 1.0499 | 1.0393 | |
| HCC1187 | TNBC | Basal A | GSK1838705A | IGF1R | RTK | 0.0384 | uM | 7433.071 | 1.0062 | 1.0119 | 1.0393 | |
| HCC1187 | TNBC | Basal A | GSK1838705A | IGF1R | RTK | 0.192 | uM | 7433.071 | 0.9849 | 0.9709 | 1.0393 | |
| HCC1187 | TNBC | Basal A | GSK1838705A | IGF1R | RTK | 0.96 | uM | 7433.071 | 0.9188 | 0.8435 | 1.0393 | |
| HCC1187 | TNBC | Basal A | GSK1838705A | IGF1R | RTK | 4.8 | uM | 7433.071 | 0.8658 | 0.7411 | 1.0393 | |
| HCC1187 | TNBC | Basal A | GSK1838705A | IGF1R | RTK | 24 | uM | 7433.071 | 0.8630 | 0.7356 | 1.0393 | |
| HCC1187 | TNBC | Basal A | GSK1838705A | IGF1R | RTK | 120 | uM | 7433.071 | 0.7229 | 0.4637 | 1.0393 | |
| HCC1187 | TNBC | Basal A | GSK1838705A | IGF1R | RTK | 0.000341 | uM | 7433.09 | 1.0596 | 1.1415 | 0.8477 | |
| HCC1187 | TNBC | Basal A | GSK1838705A | IGF1R | RTK | 0.00171 | uM | 7433.09 | 1.0885 | 1.2104 | 0.8477 | |
| HCC1187 | TNBC | Basal A | GSK1838705A | IGF1R | RTK | 0.00853 | uM | 7433.09 | 1.0927 | 1.2204 | 0.8477 | |
| HCC1187 | TNBC | Basal A | GSK1838705A | IGF1R | RTK | 0.0427 | uM | 7433.09 | 1.0988 | 1.2351 | 0.8477 | |
| HCC1187 | TNBC | Basal A | GSK1838705A | IGF1R | RTK | 0.213 | uM | 7433.09 | 0.9950 | 0.9882 | 0.8477 | |
| HCC1187 | TNBC | Basal A | GSK1838705A | IGF1R | RTK | 1.07 | uM | 7433.09 | 0.9464 | 0.8741 | 0.8477 | |
| HCC1187 | TNBC | Basal A | GSK1838705A | IGF1R | RTK | 5.33 | uM | 7433.09 | 0.7263 | 0.3716 | 0.8477 | |
| HCC1187 | TNBC | Basal A | GSK1838705A | IGF1R | RTK | 26.7 | uM | 7433.09 | 0.7421 | 0.4067 | 0.8477 | |
| HCC1187 | TNBC | Basal A | GSK1838705A | IGF1R | RTK | 133 | uM | 7433.09 | 0.7433 | 0.4094 | 0.8477 | |
| HCC1187 | TNBC | Basal A | GSK1838705A | IGF1R | RTK | 0.000171 | uM | 7433.098 | 0.9300 | 0.8765 | 1.1392 | |
| HCC1187 | TNBC | Basal A | GSK1838705A | IGF1R | RTK | 0.000853 | uM | 7433.098 | 1.0118 | 1.0207 | 1.1392 | |
| HCC1187 | TNBC | Basal A | GSK1838705A | IGF1R | RTK | 0.00427 | uM | 7433.098 | 0.9775 | 0.9604 | 1.1392 | |
| HCC1187 | TNBC | Basal A | GSK1838705A | IGF1R | RTK | 0.0213 | uM | 7433.098 | 0.9718 | 0.9504 | 1.1392 | |
| HCC1187 | TNBC | Basal A | GSK1838705A | IGF1R | RTK | 0.107 | uM | 7433.098 | 0.8913 | 0.8079 | 1.1392 | |
| HCC1187 | TNBC | Basal A | GSK1838705A | IGF1R | RTK | 0.533 | uM | 7433.098 | 0.8914 | 0.8080 | 1.1392 | |
| HCC1187 | TNBC | Basal A | GSK1838705A | IGF1R | RTK | 2.67 | uM | 7433.098 | 0.7963 | 0.6375 | 1.1392 | |
| HCC1187 | TNBC | Basal A | GSK1838705A | IGF1R | RTK | 13.3 | uM | 7433.098 | 0.1269 | -0.6734 | 1.1392 | |
| HCC1187 | TNBC | Basal A | GSK1838705A | IGF1R | RTK | 66.7 | uM | 7433.098 | 0.0116 | -0.9600 | 1.1392 |