Growth rate-corrected (GR) dose-response metrics across a panel of 71 breast cancer cell lines treated with a library of small molecule and antibody perturbagens. Dataset 1 of 4: Relative cell counts and normalized growth rate inhibition values across technical replicates. - Dataset (ID:20268)
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| Cell | Clinical Subtype | Transcriptional Subtype | Small Molecule | Antibody | Perturbagen Target | Perturbagen Class | Perturbagen Concentration | Perturbagen Conc Unit | Biological Replicate ID | Relative Cell Count | Normalized Growth Rate Inhibition Value | Nominal Division Rate |
|---|---|---|---|---|---|---|---|---|---|---|---|---|
| BT-549 | TNBC | Basal B | GSK1838705A | IGF1R | RTK | 0.533 | uM | 5910.07 | 0.9336 | 0.9590 | 3.3174 | |
| BT-549 | TNBC | Basal B | GSK1838705A | IGF1R | RTK | 2.67 | uM | 5910.07 | 0.9514 | 0.9702 | 3.3174 | |
| BT-549 | TNBC | Basal B | GSK1838705A | IGF1R | RTK | 13.3 | uM | 5910.07 | 0.8966 | 0.9353 | 3.3174 | |
| BT-549 | TNBC | Basal B | GSK1838705A | IGF1R | RTK | 66.7 | uM | 5910.07 | 0.8921 | 0.9323 | 3.3174 | |
| BT-549 | TNBC | Basal B | GSK1838705A | IGF1R | RTK | 0.000341 | uM | 5910.091 | 1.1125 | 1.0652 | 3.3208 | |
| BT-549 | TNBC | Basal B | GSK1838705A | IGF1R | RTK | 0.00171 | uM | 5910.091 | 1.0753 | 1.0442 | 3.3208 | |
| BT-549 | TNBC | Basal B | GSK1838705A | IGF1R | RTK | 0.00853 | uM | 5910.091 | 1.0812 | 1.0476 | 3.3208 | |
| BT-549 | TNBC | Basal B | GSK1838705A | IGF1R | RTK | 0.0427 | uM | 5910.091 | 1.0799 | 1.0468 | 3.3208 | |
| BT-549 | TNBC | Basal B | GSK1838705A | IGF1R | RTK | 0.213 | uM | 5910.091 | 1.0088 | 1.0053 | 3.3208 | |
| BT-549 | TNBC | Basal B | GSK1838705A | IGF1R | RTK | 1.07 | uM | 5910.091 | 0.9980 | 0.9988 | 3.3208 | |
| BT-549 | TNBC | Basal B | GSK1838705A | IGF1R | RTK | 5.33 | uM | 5910.091 | 0.5786 | 0.6962 | 3.3208 | |
| BT-549 | TNBC | Basal B | GSK1838705A | IGF1R | RTK | 26.7 | uM | 5910.091 | 1.1745 | 1.0992 | 3.3208 | |
| BT-549 | TNBC | Basal B | GSK1838705A | IGF1R | RTK | 133 | uM | 5910.091 | 0.9713 | 0.9825 | 3.3208 | |
| BT-549 | TNBC | Basal B | GSK1838705A | IGF1R | RTK | 0.000171 | uM | 5910.098 | 1.0956 | 1.0578 | 3.2046 | |
| BT-549 | TNBC | Basal B | GSK1838705A | IGF1R | RTK | 0.000853 | uM | 5910.098 | 1.1275 | 1.0763 | 3.2046 | |
| BT-549 | TNBC | Basal B | GSK1838705A | IGF1R | RTK | 0.00427 | uM | 5910.098 | 0.9981 | 0.9988 | 3.2046 | |
| BT-549 | TNBC | Basal B | GSK1838705A | IGF1R | RTK | 0.0213 | uM | 5910.098 | 0.9967 | 0.9980 | 3.2046 | |
| BT-549 | TNBC | Basal B | GSK1838705A | IGF1R | RTK | 0.107 | uM | 5910.098 | 0.9958 | 0.9974 | 3.2046 | |
| BT-549 | TNBC | Basal B | GSK1838705A | IGF1R | RTK | 0.533 | uM | 5910.098 | 1.0922 | 1.0558 | 3.2046 | |
| BT-549 | TNBC | Basal B | GSK1838705A | IGF1R | RTK | 2.67 | uM | 5910.098 | 0.9316 | 0.9563 | 3.2046 | |
| BT-549 | TNBC | Basal B | GSK1838705A | IGF1R | RTK | 13.3 | uM | 5910.098 | 0.1057 | -0.0081 | 3.2046 | |
| BT-549 | TNBC | Basal B | GSK1838705A | IGF1R | RTK | 66.7 | uM | 5910.098 | 0.0005 | -0.8174 | 3.2046 | |
| CAMA-1 | HR+ | Luminal | GSK1838705A | IGF1R | RTK | 0.000171 | uM | 5911.07 | 0.9317 | 0.8722 | 1.0709 | |
| CAMA-1 | HR+ | Luminal | GSK1838705A | IGF1R | RTK | 0.000853 | uM | 5911.07 | 0.9579 | 0.9213 | 1.0709 | |
| CAMA-1 | HR+ | Luminal | GSK1838705A | IGF1R | RTK | 0.00427 | uM | 5911.07 | 0.9726 | 0.9488 | 1.0709 |