Growth rate-corrected (GR) dose-response metrics across a panel of 71 breast cancer cell lines treated with a library of small molecule and antibody perturbagens. Dataset 1 of 4: Relative cell counts and normalized growth rate inhibition values across technical replicates. - Dataset (ID:20268)
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| Cell | Clinical Subtype | Transcriptional Subtype | Small Molecule | Antibody | Perturbagen Target | Perturbagen Class | Perturbagen Concentration | Perturbagen Conc Unit | Biological Replicate ID | Relative Cell Count | Normalized Growth Rate Inhibition Value | Nominal Division Rate |
|---|---|---|---|---|---|---|---|---|---|---|---|---|
| UACC-812 | HER2amp | Luminal | Glycyl-H-1152 | ROCK2 | 2.67 | uM | 11938.16 | 0.9843 | 0.9512 | 0.6405 | ||
| UACC-812 | HER2amp | Luminal | Glycyl-H-1152 | ROCK2 | 13.3 | uM | 11938.16 | 0.9725 | 0.9148 | 0.6405 | ||
| UACC-812 | HER2amp | Luminal | Glycyl-H-1152 | ROCK2 | 66.7 | uM | 11938.16 | 0.9789 | 0.9344 | 0.6405 | ||
| ZR-75-1 | HR+ | Luminal | Glycyl-H-1152 | ROCK2 | 0.0000853 | uM | 11660.15 | 0.9803 | 0.9605 | 0.9958 | ||
| ZR-75-1 | HR+ | Luminal | Glycyl-H-1152 | ROCK2 | 0.000427 | uM | 11660.15 | 0.9011 | 0.8014 | 0.9958 | ||
| ZR-75-1 | HR+ | Luminal | Glycyl-H-1152 | ROCK2 | 0.00213 | uM | 11660.15 | 0.9043 | 0.8079 | 0.9958 | ||
| ZR-75-1 | HR+ | Luminal | Glycyl-H-1152 | ROCK2 | 0.0107 | uM | 11660.15 | 0.9561 | 0.9118 | 0.9958 | ||
| ZR-75-1 | HR+ | Luminal | Glycyl-H-1152 | ROCK2 | 0.0533 | uM | 11660.15 | 0.9577 | 0.9150 | 0.9958 | ||
| ZR-75-1 | HR+ | Luminal | Glycyl-H-1152 | ROCK2 | 0.267 | uM | 11660.15 | 0.9065 | 0.8122 | 0.9958 | ||
| ZR-75-1 | HR+ | Luminal | Glycyl-H-1152 | ROCK2 | 1.33 | uM | 11660.15 | 0.8145 | 0.6276 | 0.9958 | ||
| ZR-75-1 | HR+ | Luminal | Glycyl-H-1152 | ROCK2 | 6.67 | uM | 11660.15 | 0.7413 | 0.4807 | 0.9958 | ||
| ZR-75-1 | HR+ | Luminal | Glycyl-H-1152 | ROCK2 | 33.3 | uM | 11660.15 | 0.7207 | 0.4393 | 0.9958 | ||
| ZR-75-1 | HR+ | Luminal | Glycyl-H-1152 | ROCK2 | 0.000171 | uM | 12003.169 | 0.9352 | 0.8771 | 1.0562 | ||
| ZR-75-1 | HR+ | Luminal | Glycyl-H-1152 | ROCK2 | 0.000853 | uM | 12003.169 | 1.0008 | 1.0014 | 1.0562 | ||
| ZR-75-1 | HR+ | Luminal | Glycyl-H-1152 | ROCK2 | 0.00427 | uM | 12003.169 | 0.8922 | 0.7953 | 1.0562 | ||
| ZR-75-1 | HR+ | Luminal | Glycyl-H-1152 | ROCK2 | 0.0213 | uM | 12003.169 | 0.9516 | 0.9083 | 1.0562 | ||
| ZR-75-1 | HR+ | Luminal | Glycyl-H-1152 | ROCK2 | 0.107 | uM | 12003.169 | 0.9375 | 0.8815 | 1.0562 | ||
| ZR-75-1 | HR+ | Luminal | Glycyl-H-1152 | ROCK2 | 0.533 | uM | 12003.169 | 0.9293 | 0.8659 | 1.0562 | ||
| ZR-75-1 | HR+ | Luminal | Glycyl-H-1152 | ROCK2 | 2.67 | uM | 12003.169 | 0.8992 | 0.8086 | 1.0562 | ||
| ZR-75-1 | HR+ | Luminal | Glycyl-H-1152 | ROCK2 | 13.3 | uM | 12003.169 | 0.9273 | 0.8621 | 1.0562 | ||
| ZR-75-1 | HR+ | Luminal | Glycyl-H-1152 | ROCK2 | 66.7 | uM | 12003.169 | 0.8513 | 0.7172 | 1.0562 | ||
| ZR75B | HR+ | Luminal | Glycyl-H-1152 | ROCK2 | 0.000171 | uM | 11939.16 | 0.9452 | 0.9338 | 1.6749 | ||
| ZR75B | HR+ | Luminal | Glycyl-H-1152 | ROCK2 | 0.000853 | uM | 11939.16 | 0.9645 | 0.9573 | 1.6749 | ||
| ZR75B | HR+ | Luminal | Glycyl-H-1152 | ROCK2 | 0.00427 | uM | 11939.16 | 0.9457 | 0.9344 | 1.6749 | ||
| ZR75B | HR+ | Luminal | Glycyl-H-1152 | ROCK2 | 0.0213 | uM | 11939.16 | 0.9195 | 0.9023 | 1.6749 |