Growth rate-corrected (GR) dose-response metrics across a panel of 71 breast cancer cell lines treated with a library of small molecule and antibody perturbagens. Dataset 1 of 4: Relative cell counts and normalized growth rate inhibition values across technical replicates. - Dataset (ID:20268)
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| Cell | Clinical Subtype | Transcriptional Subtype | Small Molecule | Antibody | Perturbagen Target | Perturbagen Class | Perturbagen Concentration | Perturbagen Conc Unit | Biological Replicate ID | Relative Cell Count | Normalized Growth Rate Inhibition Value | Nominal Division Rate |
|---|---|---|---|---|---|---|---|---|---|---|---|---|
| ZR75B | HR+ | Luminal | Glycyl-H-1152 | ROCK2 | 0.107 | uM | 11939.16 | 0.9441 | 0.9325 | 1.6749 | ||
| ZR75B | HR+ | Luminal | Glycyl-H-1152 | ROCK2 | 0.533 | uM | 11939.16 | 0.8072 | 0.7599 | 1.6749 | ||
| ZR75B | HR+ | Luminal | Glycyl-H-1152 | ROCK2 | 2.67 | uM | 11939.16 | 0.6944 | 0.6086 | 1.6749 | ||
| ZR75B | HR+ | Luminal | Glycyl-H-1152 | ROCK2 | 13.3 | uM | 11939.16 | 0.6060 | 0.4831 | 1.6749 | ||
| ZR75B | HR+ | Luminal | Glycyl-H-1152 | ROCK2 | 66.7 | uM | 11939.16 | 0.8267 | 0.7851 | 1.6749 | ||
| 184A1 | NM | Basal | GM6001 | MMP | MMP | 0.0000853 | uM | 5895.096 | 1.0478 | 1.0667 | 1.4232 | |
| 184A1 | NM | Basal | GM6001 | MMP | MMP | 0.000427 | uM | 5895.096 | 1.0170 | 1.0238 | 1.4232 | |
| 184A1 | NM | Basal | GM6001 | MMP | MMP | 0.00213 | uM | 5895.096 | 1.0006 | 1.0009 | 1.4232 | |
| 184A1 | NM | Basal | GM6001 | MMP | MMP | 0.0107 | uM | 5895.096 | 1.0212 | 1.0298 | 1.4232 | |
| 184A1 | NM | Basal | GM6001 | MMP | MMP | 0.0533 | uM | 5895.096 | 1.0513 | 1.0715 | 1.4232 | |
| 184A1 | NM | Basal | GM6001 | MMP | MMP | 0.267 | uM | 5895.096 | 1.0249 | 1.0349 | 1.4232 | |
| 184A1 | NM | Basal | GM6001 | MMP | MMP | 1.33 | uM | 5895.096 | 0.9542 | 0.9352 | 1.4232 | |
| 184A1 | NM | Basal | GM6001 | MMP | MMP | 6.67 | uM | 5895.096 | 1.0178 | 1.0250 | 1.4232 | |
| 184A1 | NM | Basal | GM6001 | MMP | MMP | 33.3 | uM | 5895.096 | 0.9832 | 0.9763 | 1.4232 | |
| 184B5 | NM | Basal | GM6001 | MMP | MMP | 0.0000853 | uM | 5897.096 | 0.9669 | 0.9482 | 1.2810 | |
| 184B5 | NM | Basal | GM6001 | MMP | MMP | 0.000427 | uM | 5897.096 | 0.9893 | 0.9832 | 1.2810 | |
| 184B5 | NM | Basal | GM6001 | MMP | MMP | 0.00213 | uM | 5897.096 | 0.9937 | 0.9901 | 1.2810 | |
| 184B5 | NM | Basal | GM6001 | MMP | MMP | 0.0107 | uM | 5897.096 | 0.9646 | 0.9445 | 1.2810 | |
| 184B5 | NM | Basal | GM6001 | MMP | MMP | 0.0533 | uM | 5897.096 | 1.0235 | 1.0366 | 1.2810 | |
| 184B5 | NM | Basal | GM6001 | MMP | MMP | 0.267 | uM | 5897.096 | 0.9760 | 0.9625 | 1.2810 | |
| 184B5 | NM | Basal | GM6001 | MMP | MMP | 1.33 | uM | 5897.096 | 1.0007 | 1.0010 | 1.2810 | |
| 184B5 | NM | Basal | GM6001 | MMP | MMP | 6.67 | uM | 5897.096 | 0.9738 | 0.9590 | 1.2810 | |
| 184B5 | NM | Basal | GM6001 | MMP | MMP | 33.3 | uM | 5897.096 | 0.9800 | 0.9688 | 1.2810 | |
| 600MPE | HR+ | Luminal | GM6001 | MMP | MMP | 0.0000853 | uM | 5898.096 | 0.9695 | 0.9098 | 0.6718 | |
| 600MPE | HR+ | Luminal | GM6001 | MMP | MMP | 0.000427 | uM | 5898.096 | 0.9772 | 0.9325 | 0.6718 |