Growth rate-corrected (GR) dose-response metrics across a panel of 71 breast cancer cell lines treated with a library of small molecule and antibody perturbagens. Dataset 1 of 4: Relative cell counts and normalized growth rate inhibition values across technical replicates. - Dataset (ID:20268)
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| Cell | Clinical Subtype | Transcriptional Subtype | Small Molecule | Antibody | Perturbagen Target | Perturbagen Class | Perturbagen Concentration | Perturbagen Conc Unit | Biological Replicate ID | Relative Cell Count | Normalized Growth Rate Inhibition Value | Nominal Division Rate |
|---|---|---|---|---|---|---|---|---|---|---|---|---|
| SUM52PE | HR+ | Luminal | Glycyl-H-1152 | ROCK2 | 0.000853 | uM | 11852.16 | 1.0030 | 1.0049 | 1.2383 | ||
| SUM52PE | HR+ | Luminal | Glycyl-H-1152 | ROCK2 | 0.00427 | uM | 11852.16 | 0.9466 | 0.9133 | 1.2383 | ||
| SUM52PE | HR+ | Luminal | Glycyl-H-1152 | ROCK2 | 0.0213 | uM | 11852.16 | 1.0280 | 1.0451 | 1.2383 | ||
| SUM52PE | HR+ | Luminal | Glycyl-H-1152 | ROCK2 | 0.107 | uM | 11852.16 | 0.9485 | 0.9164 | 1.2383 | ||
| SUM52PE | HR+ | Luminal | Glycyl-H-1152 | ROCK2 | 0.533 | uM | 11852.16 | 1.0155 | 1.0250 | 1.2383 | ||
| SUM52PE | HR+ | Luminal | Glycyl-H-1152 | ROCK2 | 2.67 | uM | 11852.16 | 0.9890 | 0.9822 | 1.2383 | ||
| SUM52PE | HR+ | Luminal | Glycyl-H-1152 | ROCK2 | 13.3 | uM | 11852.16 | 0.7329 | 0.5561 | 1.2383 | ||
| SUM52PE | HR+ | Luminal | Glycyl-H-1152 | ROCK2 | 66.7 | uM | 11852.16 | 0.5023 | 0.1470 | 1.2383 | ||
| T47D | HR+ | Luminal | Glycyl-H-1152 | ROCK2 | 0.0000853 | uM | 10939.15 | 0.9692 | 0.9632 | 1.6881 | ||
| T47D | HR+ | Luminal | Glycyl-H-1152 | ROCK2 | 0.000427 | uM | 10939.15 | 0.9363 | 0.9235 | 1.6881 | ||
| T47D | HR+ | Luminal | Glycyl-H-1152 | ROCK2 | 0.00213 | uM | 10939.15 | 0.9766 | 0.9722 | 1.6881 | ||
| T47D | HR+ | Luminal | Glycyl-H-1152 | ROCK2 | 0.0107 | uM | 10939.15 | 0.9549 | 0.9461 | 1.6881 | ||
| T47D | HR+ | Luminal | Glycyl-H-1152 | ROCK2 | 0.0533 | uM | 10939.15 | 0.9545 | 0.9456 | 1.6881 | ||
| T47D | HR+ | Luminal | Glycyl-H-1152 | ROCK2 | 0.267 | uM | 10939.15 | 0.9631 | 0.9560 | 1.6881 | ||
| T47D | HR+ | Luminal | Glycyl-H-1152 | ROCK2 | 1.33 | uM | 10939.15 | 0.9134 | 0.8955 | 1.6881 | ||
| T47D | HR+ | Luminal | Glycyl-H-1152 | ROCK2 | 6.67 | uM | 10939.15 | 0.7702 | 0.7134 | 1.6881 | ||
| T47D | HR+ | Luminal | Glycyl-H-1152 | ROCK2 | 33.3 | uM | 10939.15 | 0.5861 | 0.4574 | 1.6881 | ||
| T47DKBLUC | Unknown | Unknown | Glycyl-H-1152 | ROCK2 | 0.000171 | uM | 12608.169 | 1.0387 | 1.0614 | 1.2559 | ||
| T47DKBLUC | Unknown | Unknown | Glycyl-H-1152 | ROCK2 | 0.000853 | uM | 12608.169 | 0.9466 | 0.9145 | 1.2559 | ||
| T47DKBLUC | Unknown | Unknown | Glycyl-H-1152 | ROCK2 | 0.00427 | uM | 12608.169 | 0.9756 | 0.9610 | 1.2559 | ||
| T47DKBLUC | Unknown | Unknown | Glycyl-H-1152 | ROCK2 | 0.0213 | uM | 12608.169 | 0.9596 | 0.9355 | 1.2559 | ||
| T47DKBLUC | Unknown | Unknown | Glycyl-H-1152 | ROCK2 | 0.107 | uM | 12608.169 | 1.0153 | 1.0243 | 1.2559 | ||
| T47DKBLUC | Unknown | Unknown | Glycyl-H-1152 | ROCK2 | 0.533 | uM | 12608.169 | 1.0037 | 1.0059 | 1.2559 | ||
| T47DKBLUC | Unknown | Unknown | Glycyl-H-1152 | ROCK2 | 2.67 | uM | 12608.169 | 1.0956 | 1.1509 | 1.2559 | ||
| T47DKBLUC | Unknown | Unknown | Glycyl-H-1152 | ROCK2 | 13.3 | uM | 12608.169 | 1.0305 | 1.0484 | 1.2559 |