Growth rate-corrected (GR) dose-response metrics across a panel of 71 breast cancer cell lines treated with a library of small molecule and antibody perturbagens. Dataset 1 of 4: Relative cell counts and normalized growth rate inhibition values across technical replicates. - Dataset (ID:20268)
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| Cell | Clinical Subtype | Transcriptional Subtype | Small Molecule | Antibody | Perturbagen Target | Perturbagen Class | Perturbagen Concentration | Perturbagen Conc Unit | Biological Replicate ID | Relative Cell Count | Normalized Growth Rate Inhibition Value | Nominal Division Rate |
|---|---|---|---|---|---|---|---|---|---|---|---|---|
| HCC1569 | HER2amp | Basal A | Glycyl-H-1152 | ROCK2 | 0.000427 | uM | 10872.15 | 0.9410 | 0.9265 | 1.6255 | ||
| HCC1569 | HER2amp | Basal A | Glycyl-H-1152 | ROCK2 | 0.00213 | uM | 10872.15 | 0.9563 | 0.9458 | 1.6255 | ||
| HCC1569 | HER2amp | Basal A | Glycyl-H-1152 | ROCK2 | 0.0107 | uM | 10872.15 | 0.9780 | 0.9729 | 1.6255 | ||
| HCC1569 | HER2amp | Basal A | Glycyl-H-1152 | ROCK2 | 0.0533 | uM | 10872.15 | 0.8801 | 0.8489 | 1.6255 | ||
| HCC1569 | HER2amp | Basal A | Glycyl-H-1152 | ROCK2 | 0.267 | uM | 10872.15 | 0.9485 | 0.9360 | 1.6255 | ||
| HCC1569 | HER2amp | Basal A | Glycyl-H-1152 | ROCK2 | 1.33 | uM | 10872.15 | 0.8695 | 0.8351 | 1.6255 | ||
| HCC1569 | HER2amp | Basal A | Glycyl-H-1152 | ROCK2 | 6.67 | uM | 10872.15 | 0.6340 | 0.5110 | 1.6255 | ||
| HCC1569 | HER2amp | Basal A | Glycyl-H-1152 | ROCK2 | 33.3 | uM | 10872.15 | 0.4191 | 0.1713 | 1.6255 | ||
| HCC1569 | HER2amp | Basal A | Glycyl-H-1152 | ROCK2 | 0.000171 | uM | 12523.169 | 1.0435 | 1.0829 | 1.0498 | ||
| HCC1569 | HER2amp | Basal A | Glycyl-H-1152 | ROCK2 | 0.000853 | uM | 12523.169 | 0.9499 | 0.9045 | 1.0498 | ||
| HCC1569 | HER2amp | Basal A | Glycyl-H-1152 | ROCK2 | 0.00427 | uM | 12523.169 | 1.0056 | 1.0107 | 1.0498 | ||
| HCC1569 | HER2amp | Basal A | Glycyl-H-1152 | ROCK2 | 0.0213 | uM | 12523.169 | 0.9751 | 0.9526 | 1.0498 | ||
| HCC1569 | HER2amp | Basal A | Glycyl-H-1152 | ROCK2 | 0.107 | uM | 12523.169 | 1.0364 | 1.0694 | 1.0498 | ||
| HCC1569 | HER2amp | Basal A | Glycyl-H-1152 | ROCK2 | 0.533 | uM | 12523.169 | 1.0142 | 1.0271 | 1.0498 | ||
| HCC1569 | HER2amp | Basal A | Glycyl-H-1152 | ROCK2 | 2.67 | uM | 12523.169 | 0.7932 | 0.6040 | 1.0498 | ||
| HCC1569 | HER2amp | Basal A | Glycyl-H-1152 | ROCK2 | 13.3 | uM | 12523.169 | 0.6649 | 0.3557 | 1.0498 | ||
| HCC1569 | HER2amp | Basal A | Glycyl-H-1152 | ROCK2 | 66.7 | uM | 12523.169 | 0.5103 | 0.0536 | 1.0498 | ||
| HCC1806 | TNBC | Basal A | Glycyl-H-1152 | ROCK2 | 0.000171 | uM | 12239.16 | 1.0763 | 1.0804 | 1.8654 | ||
| HCC1806 | TNBC | Basal A | Glycyl-H-1152 | ROCK2 | 0.000853 | uM | 12239.16 | 1.0166 | 1.0177 | 1.8654 | ||
| HCC1806 | TNBC | Basal A | Glycyl-H-1152 | ROCK2 | 0.00427 | uM | 12239.16 | 1.0348 | 1.0370 | 1.8654 | ||
| HCC1806 | TNBC | Basal A | Glycyl-H-1152 | ROCK2 | 0.0213 | uM | 12239.16 | 1.0153 | 1.0163 | 1.8654 | ||
| HCC1806 | TNBC | Basal A | Glycyl-H-1152 | ROCK2 | 0.107 | uM | 12239.16 | 1.0554 | 1.0587 | 1.8654 | ||
| HCC1806 | TNBC | Basal A | Glycyl-H-1152 | ROCK2 | 0.533 | uM | 12239.16 | 1.0294 | 1.0313 | 1.8654 | ||
| HCC1806 | TNBC | Basal A | Glycyl-H-1152 | ROCK2 | 2.67 | uM | 12239.16 | 0.9521 | 0.9481 | 1.8654 | ||
| HCC1806 | TNBC | Basal A | Glycyl-H-1152 | ROCK2 | 13.3 | uM | 12239.16 | 0.8123 | 0.7890 | 1.8654 |