Growth rate-corrected (GR) dose-response metrics across a panel of 71 breast cancer cell lines treated with a library of small molecule and antibody perturbagens. Dataset 1 of 4: Relative cell counts and normalized growth rate inhibition values across technical replicates. - Dataset (ID:20268)
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| Cell | Clinical Subtype | Transcriptional Subtype | Small Molecule | Antibody | Perturbagen Target | Perturbagen Class | Perturbagen Concentration | Perturbagen Conc Unit | Biological Replicate ID | Relative Cell Count | Normalized Growth Rate Inhibition Value | Nominal Division Rate |
|---|---|---|---|---|---|---|---|---|---|---|---|---|
| SUM159PT | TNBC | Basal B | Gefitinib | EGFR | ErbB | 0.0000853 | uM | 7920.016 | 1.0137 | 1.0063 | 4.3230 | |
| SUM159PT | TNBC | Basal B | Gefitinib | EGFR | ErbB | 0.000427 | uM | 7920.016 | 1.1164 | 1.0516 | 4.3230 | |
| SUM159PT | TNBC | Basal B | Gefitinib | EGFR | ErbB | 0.00213 | uM | 7920.016 | 1.0407 | 1.0185 | 4.3230 | |
| SUM159PT | TNBC | Basal B | Gefitinib | EGFR | ErbB | 0.0107 | uM | 7920.016 | 1.0791 | 1.0355 | 4.3230 | |
| SUM159PT | TNBC | Basal B | Gefitinib | EGFR | ErbB | 0.0533 | uM | 7920.016 | 1.1228 | 1.0543 | 4.3230 | |
| SUM159PT | TNBC | Basal B | Gefitinib | EGFR | ErbB | 0.267 | uM | 7920.016 | 1.0662 | 1.0299 | 4.3230 | |
| SUM159PT | TNBC | Basal B | Gefitinib | EGFR | ErbB | 1.33 | uM | 7920.016 | 0.9112 | 0.9574 | 4.3230 | |
| SUM159PT | TNBC | Basal B | Gefitinib | EGFR | ErbB | 6.67 | uM | 7920.016 | 0.9371 | 0.9702 | 4.3230 | |
| SUM159PT | TNBC | Basal B | Gefitinib | EGFR | ErbB | 33.3 | uM | 7920.016 | 0.1759 | 0.3380 | 4.3230 | |
| SUM159PT | TNBC | Basal B | Gefitinib | EGFR | ErbB | 0.0000853 | uM | 9042.016 | 0.9933 | 0.9953 | 2.8524 | |
| SUM159PT | TNBC | Basal B | Gefitinib | EGFR | ErbB | 0.000427 | uM | 9042.016 | 1.0709 | 1.0486 | 2.8524 | |
| SUM159PT | TNBC | Basal B | Gefitinib | EGFR | ErbB | 0.00213 | uM | 9042.016 | 0.8277 | 0.8717 | 2.8524 | |
| SUM159PT | TNBC | Basal B | Gefitinib | EGFR | ErbB | 0.0107 | uM | 9042.016 | 1.0909 | 1.0620 | 2.8524 | |
| SUM159PT | TNBC | Basal B | Gefitinib | EGFR | ErbB | 0.0533 | uM | 9042.016 | 1.0586 | 1.0403 | 2.8524 | |
| SUM159PT | TNBC | Basal B | Gefitinib | EGFR | ErbB | 0.267 | uM | 9042.016 | 1.0600 | 1.0413 | 2.8524 | |
| SUM159PT | TNBC | Basal B | Gefitinib | EGFR | ErbB | 1.33 | uM | 9042.016 | 0.9779 | 0.9844 | 2.8524 | |
| SUM159PT | TNBC | Basal B | Gefitinib | EGFR | ErbB | 6.67 | uM | 9042.016 | 0.6283 | 0.6993 | 2.8524 | |
| SUM159PT | TNBC | Basal B | Gefitinib | EGFR | ErbB | 33.3 | uM | 9042.016 | 0.1790 | 0.0942 | 2.8524 | |
| SUM185PE | TNBC | Luminal | Gefitinib | EGFR | ErbB | 0.0000853 | uM | 7921.016 | 1.0473 | 1.1446 | 0.6622 | |
| SUM185PE | TNBC | Luminal | Gefitinib | EGFR | ErbB | 0.000427 | uM | 7921.016 | 1.0143 | 1.0432 | 0.6622 | |
| SUM185PE | TNBC | Luminal | Gefitinib | EGFR | ErbB | 0.00213 | uM | 7921.016 | 0.9920 | 0.9759 | 0.6622 | |
| SUM185PE | TNBC | Luminal | Gefitinib | EGFR | ErbB | 0.0107 | uM | 7921.016 | 1.0364 | 1.1111 | 0.6622 | |
| SUM185PE | TNBC | Luminal | Gefitinib | EGFR | ErbB | 0.0533 | uM | 7921.016 | 1.0029 | 1.0088 | 0.6622 | |
| SUM185PE | TNBC | Luminal | Gefitinib | EGFR | ErbB | 0.267 | uM | 7921.016 | 1.0229 | 1.0697 | 0.6622 | |
| SUM185PE | TNBC | Luminal | Gefitinib | EGFR | ErbB | 1.33 | uM | 7921.016 | 1.0203 | 1.0616 | 0.6622 |