Growth rate-corrected (GR) dose-response metrics across a panel of 71 breast cancer cell lines treated with a library of small molecule and antibody perturbagens. Dataset 1 of 4: Relative cell counts and normalized growth rate inhibition values across technical replicates. - Dataset (ID:20268)
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| Cell | Clinical Subtype | Transcriptional Subtype | Small Molecule | Antibody | Perturbagen Target | Perturbagen Class | Perturbagen Concentration | Perturbagen Conc Unit | Biological Replicate ID | Relative Cell Count | Normalized Growth Rate Inhibition Value | Nominal Division Rate |
|---|---|---|---|---|---|---|---|---|---|---|---|---|
| MDA-MB-361 | HER2amp | Luminal | Gefitinib | EGFR | ErbB | 0.00213 | uM | 7894.016 | 0.9889 | 0.9713 | 0.7753 | |
| MDA-MB-361 | HER2amp | Luminal | Gefitinib | EGFR | ErbB | 0.0107 | uM | 7894.016 | 0.9665 | 0.9139 | 0.7753 | |
| MDA-MB-361 | HER2amp | Luminal | Gefitinib | EGFR | ErbB | 0.0533 | uM | 7894.016 | 0.9716 | 0.9269 | 0.7753 | |
| MDA-MB-361 | HER2amp | Luminal | Gefitinib | EGFR | ErbB | 0.267 | uM | 7894.016 | 1.0270 | 1.0699 | 0.7753 | |
| MDA-MB-361 | HER2amp | Luminal | Gefitinib | EGFR | ErbB | 1.33 | uM | 7894.016 | 0.9131 | 0.7786 | 0.7753 | |
| MDA-MB-361 | HER2amp | Luminal | Gefitinib | EGFR | ErbB | 6.67 | uM | 7894.016 | 0.8674 | 0.6648 | 0.7753 | |
| MDA-MB-361 | HER2amp | Luminal | Gefitinib | EGFR | ErbB | 33.3 | uM | 7894.016 | 0.6557 | 0.1604 | 0.7753 | |
| MDA-MB-361 | HER2amp | Luminal | Gefitinib | EGFR | ErbB | 0.0000853 | uM | 7895.016 | 0.9948 | 0.9920 | 1.2977 | |
| MDA-MB-361 | HER2amp | Luminal | Gefitinib | EGFR | ErbB | 0.000427 | uM | 7895.016 | 0.9918 | 0.9874 | 1.2977 | |
| MDA-MB-361 | HER2amp | Luminal | Gefitinib | EGFR | ErbB | 0.00213 | uM | 7895.016 | 0.9494 | 0.9215 | 1.2977 | |
| MDA-MB-361 | HER2amp | Luminal | Gefitinib | EGFR | ErbB | 0.0107 | uM | 7895.016 | 1.0224 | 1.0345 | 1.2977 | |
| MDA-MB-361 | HER2amp | Luminal | Gefitinib | EGFR | ErbB | 0.0533 | uM | 7895.016 | 0.9904 | 0.9852 | 1.2977 | |
| MDA-MB-361 | HER2amp | Luminal | Gefitinib | EGFR | ErbB | 0.267 | uM | 7895.016 | 0.9567 | 0.9330 | 1.2977 | |
| MDA-MB-361 | HER2amp | Luminal | Gefitinib | EGFR | ErbB | 1.33 | uM | 7895.016 | 0.8970 | 0.8393 | 1.2977 | |
| MDA-MB-361 | HER2amp | Luminal | Gefitinib | EGFR | ErbB | 6.67 | uM | 7895.016 | 0.6931 | 0.5079 | 1.2977 | |
| MDA-MB-361 | HER2amp | Luminal | Gefitinib | EGFR | ErbB | 33.3 | uM | 7895.016 | 0.2137 | -0.3911 | 1.2977 | |
| MDA-MB-361 | HER2amp | Luminal | Gefitinib | EGFR | ErbB | 0.0000853 | uM | 7896.016 | 1.0253 | 1.0569 | 0.8912 | |
| MDA-MB-361 | HER2amp | Luminal | Gefitinib | EGFR | ErbB | 0.000427 | uM | 7896.016 | 0.9771 | 0.9486 | 0.8912 | |
| MDA-MB-361 | HER2amp | Luminal | Gefitinib | EGFR | ErbB | 0.00213 | uM | 7896.016 | 0.9878 | 0.9727 | 0.8912 | |
| MDA-MB-361 | HER2amp | Luminal | Gefitinib | EGFR | ErbB | 0.0107 | uM | 7896.016 | 1.0167 | 1.0376 | 0.8912 | |
| MDA-MB-361 | HER2amp | Luminal | Gefitinib | EGFR | ErbB | 0.0533 | uM | 7896.016 | 0.9805 | 0.9563 | 0.8912 | |
| MDA-MB-361 | HER2amp | Luminal | Gefitinib | EGFR | ErbB | 0.267 | uM | 7896.016 | 0.9945 | 0.9877 | 0.8912 | |
| MDA-MB-361 | HER2amp | Luminal | Gefitinib | EGFR | ErbB | 1.33 | uM | 7896.016 | 0.9634 | 0.9181 | 0.8912 | |
| MDA-MB-361 | HER2amp | Luminal | Gefitinib | EGFR | ErbB | 6.67 | uM | 7896.016 | 0.7591 | 0.4679 | 0.8912 | |
| MDA-MB-361 | HER2amp | Luminal | Gefitinib | EGFR | ErbB | 33.3 | uM | 7896.016 | 0.3333 | -0.4171 | 0.8912 |