Growth rate-corrected (GR) dose-response metrics across a panel of 71 breast cancer cell lines treated with a library of small molecule and antibody perturbagens. Dataset 1 of 4: Relative cell counts and normalized growth rate inhibition values across technical replicates. - Dataset (ID:20268)
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| Cell | Clinical Subtype | Transcriptional Subtype | Small Molecule | Antibody | Perturbagen Target | Perturbagen Class | Perturbagen Concentration | Perturbagen Conc Unit | Biological Replicate ID | Relative Cell Count | Normalized Growth Rate Inhibition Value | Nominal Division Rate |
|---|---|---|---|---|---|---|---|---|---|---|---|---|
| AU565 | HER2amp | Luminal | Gefitinib | EGFR | ErbB | 0.0000853 | uM | 7793.016 | 0.9815 | 0.9681 | 1.1616 | |
| AU565 | HER2amp | Luminal | Gefitinib | EGFR | ErbB | 0.000427 | uM | 7793.016 | 0.9281 | 0.8755 | 1.1616 | |
| AU565 | HER2amp | Luminal | Gefitinib | EGFR | ErbB | 0.00213 | uM | 7793.016 | 0.9563 | 0.9246 | 1.1616 | |
| AU565 | HER2amp | Luminal | Gefitinib | EGFR | ErbB | 0.0107 | uM | 7793.016 | 1.0196 | 1.0338 | 1.1616 | |
| AU565 | HER2amp | Luminal | Gefitinib | EGFR | ErbB | 0.0533 | uM | 7793.016 | 0.9840 | 0.9724 | 1.1616 | |
| AU565 | HER2amp | Luminal | Gefitinib | EGFR | ErbB | 0.267 | uM | 7793.016 | 0.8678 | 0.7701 | 1.1616 | |
| AU565 | HER2amp | Luminal | Gefitinib | EGFR | ErbB | 1.33 | uM | 7793.016 | 0.5436 | 0.1833 | 1.1616 | |
| AU565 | HER2amp | Luminal | Gefitinib | EGFR | ErbB | 6.67 | uM | 7793.016 | 0.2592 | -0.3745 | 1.1616 | |
| AU565 | HER2amp | Luminal | Gefitinib | EGFR | ErbB | 33.3 | uM | 7793.016 | 0.1167 | -0.6853 | 1.1616 | |
| AU565 | HER2amp | Luminal | Gefitinib | EGFR | ErbB | 0.0000853 | uM | 7794.016 | 0.9975 | 0.9975 | 1.9541 | |
| AU565 | HER2amp | Luminal | Gefitinib | EGFR | ErbB | 0.000427 | uM | 7794.016 | 1.0234 | 1.0238 | 1.9541 | |
| AU565 | HER2amp | Luminal | Gefitinib | EGFR | ErbB | 0.00213 | uM | 7794.016 | 1.0150 | 1.0153 | 1.9541 | |
| AU565 | HER2amp | Luminal | Gefitinib | EGFR | ErbB | 0.0107 | uM | 7794.016 | 1.0198 | 1.0201 | 1.9541 | |
| AU565 | HER2amp | Luminal | Gefitinib | EGFR | ErbB | 0.0533 | uM | 7794.016 | 0.9864 | 0.9860 | 1.9541 | |
| AU565 | HER2amp | Luminal | Gefitinib | EGFR | ErbB | 0.267 | uM | 7794.016 | 0.8727 | 0.8654 | 1.9541 | |
| AU565 | HER2amp | Luminal | Gefitinib | EGFR | ErbB | 1.33 | uM | 7794.016 | 0.7404 | 0.7149 | 1.9541 | |
| AU565 | HER2amp | Luminal | Gefitinib | EGFR | ErbB | 6.67 | uM | 7794.016 | 0.3912 | 0.2372 | 1.9541 | |
| AU565 | HER2amp | Luminal | Gefitinib | EGFR | ErbB | 33.3 | uM | 7794.016 | 0.1711 | -0.1897 | 1.9541 | |
| AU565 | HER2amp | Luminal | Gefitinib | EGFR | ErbB | 0.0000853 | uM | 9146.049 | 0.8054 | 0.6443 | 1.1054 | |
| AU565 | HER2amp | Luminal | Gefitinib | EGFR | ErbB | 0.000427 | uM | 9146.049 | 0.9127 | 0.8414 | 1.1054 | |
| AU565 | HER2amp | Luminal | Gefitinib | EGFR | ErbB | 0.00213 | uM | 9146.049 | 0.8579 | 0.7411 | 1.1054 | |
| AU565 | HER2amp | Luminal | Gefitinib | EGFR | ErbB | 0.0107 | uM | 9146.049 | 0.8831 | 0.7873 | 1.1054 | |
| AU565 | HER2amp | Luminal | Gefitinib | EGFR | ErbB | 0.0533 | uM | 9146.049 | 0.7050 | 0.4579 | 1.1054 | |
| AU565 | HER2amp | Luminal | Gefitinib | EGFR | ErbB | 0.267 | uM | 9146.049 | 0.8073 | 0.6479 | 1.1054 | |
| AU565 | HER2amp | Luminal | Gefitinib | EGFR | ErbB | 1.33 | uM | 9146.049 | 0.7214 | 0.4883 | 1.1054 |