Growth rate-corrected (GR) dose-response metrics across a panel of 71 breast cancer cell lines treated with a library of small molecule and antibody perturbagens. Dataset 1 of 4: Relative cell counts and normalized growth rate inhibition values across technical replicates. - Dataset (ID:20268)
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| Cell | Clinical Subtype | Transcriptional Subtype | Small Molecule | Antibody | Perturbagen Target | Perturbagen Class | Perturbagen Concentration | Perturbagen Conc Unit | Biological Replicate ID | Relative Cell Count | Normalized Growth Rate Inhibition Value | Nominal Division Rate |
|---|---|---|---|---|---|---|---|---|---|---|---|---|
| MX1 | Unknown | Unknown | Fascaplysin | CDK4 | CDK | 0.0533 | uM | 7523.084 | 0.8719 | 0.7194 | 0.9069 | |
| MX1 | Unknown | Unknown | Fascaplysin | CDK4 | CDK | 0.267 | uM | 7523.084 | 0.8052 | 0.5749 | 0.9069 | |
| MX1 | Unknown | Unknown | Fascaplysin | CDK4 | CDK | 1.33 | uM | 7523.084 | 0.0063 | -0.9925 | 0.9069 | |
| MX1 | Unknown | Unknown | Fascaplysin | CDK4 | CDK | 6.67 | uM | 7523.084 | 0.0078 | -0.9905 | 0.9069 | |
| MX1 | Unknown | Unknown | Fascaplysin | CDK4 | CDK | 33.3 | uM | 7523.084 | 0.0070 | -0.9917 | 0.9069 | |
| SK-BR-3 | HER2amp | Luminal | Fascaplysin | CDK4 | CDK | 0.0000853 | uM | 7526.084 | 0.9534 | 0.9480 | 1.8115 | |
| SK-BR-3 | HER2amp | Luminal | Fascaplysin | CDK4 | CDK | 0.000427 | uM | 7526.084 | 0.9466 | 0.9404 | 1.8115 | |
| SK-BR-3 | HER2amp | Luminal | Fascaplysin | CDK4 | CDK | 0.00213 | uM | 7526.084 | 0.8893 | 0.8746 | 1.8115 | |
| SK-BR-3 | HER2amp | Luminal | Fascaplysin | CDK4 | CDK | 0.0107 | uM | 7526.084 | 0.9539 | 0.9486 | 1.8115 | |
| SK-BR-3 | HER2amp | Luminal | Fascaplysin | CDK4 | CDK | 0.0533 | uM | 7526.084 | 0.8832 | 0.8674 | 1.8115 | |
| SK-BR-3 | HER2amp | Luminal | Fascaplysin | CDK4 | CDK | 0.267 | uM | 7526.084 | 0.5776 | 0.4772 | 1.8115 | |
| SK-BR-3 | HER2amp | Luminal | Fascaplysin | CDK4 | CDK | 1.33 | uM | 7526.084 | 0.2538 | -0.0618 | 1.8115 | |
| SK-BR-3 | HER2amp | Luminal | Fascaplysin | CDK4 | CDK | 6.67 | uM | 7526.084 | 0.0118 | -0.8271 | 1.8115 | |
| SK-BR-3 | HER2amp | Luminal | Fascaplysin | CDK4 | CDK | 33.3 | uM | 7526.084 | 0.0113 | -0.8320 | 1.8115 | |
| SK-BR-3 | HER2amp | Luminal | Fascaplysin | CDK4 | CDK | 0.0000853 | uM | 7527.085 | 1.0092 | 1.0095 | 1.9392 | |
| SK-BR-3 | HER2amp | Luminal | Fascaplysin | CDK4 | CDK | 0.000427 | uM | 7527.085 | 0.9826 | 0.9820 | 1.9392 | |
| SK-BR-3 | HER2amp | Luminal | Fascaplysin | CDK4 | CDK | 0.00213 | uM | 7527.085 | 0.9699 | 0.9687 | 1.9392 | |
| SK-BR-3 | HER2amp | Luminal | Fascaplysin | CDK4 | CDK | 0.0107 | uM | 7527.085 | 1.0408 | 1.0417 | 1.9392 | |
| SK-BR-3 | HER2amp | Luminal | Fascaplysin | CDK4 | CDK | 0.0533 | uM | 7527.085 | 0.9601 | 0.9585 | 1.9392 | |
| SK-BR-3 | HER2amp | Luminal | Fascaplysin | CDK4 | CDK | 0.267 | uM | 7527.085 | 0.4840 | 0.3756 | 1.9392 | |
| SK-BR-3 | HER2amp | Luminal | Fascaplysin | CDK4 | CDK | 1.33 | uM | 7527.085 | 0.1861 | -0.1596 | 1.9392 | |
| SK-BR-3 | HER2amp | Luminal | Fascaplysin | CDK4 | CDK | 6.67 | uM | 7527.085 | 0.0090 | -0.8240 | 1.9392 | |
| SK-BR-3 | HER2amp | Luminal | Fascaplysin | CDK4 | CDK | 33.3 | uM | 7527.085 | 0.0052 | -0.8676 | 1.9392 | |
| SUM1315MO2 | TNBC | Basal B | Fascaplysin | CDK4 | CDK | 0.0000853 | uM | 7528.084 | 1.0114 | 1.0223 | 1.0247 | |
| SUM1315MO2 | TNBC | Basal B | Fascaplysin | CDK4 | CDK | 0.000427 | uM | 7528.084 | 1.0244 | 1.0475 | 1.0247 |