Growth rate-corrected (GR) dose-response metrics across a panel of 71 breast cancer cell lines treated with a library of small molecule and antibody perturbagens. Dataset 1 of 4: Relative cell counts and normalized growth rate inhibition values across technical replicates. - Dataset (ID:20268)
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| Cell | Clinical Subtype | Transcriptional Subtype | Small Molecule | Antibody | Perturbagen Target | Perturbagen Class | Perturbagen Concentration | Perturbagen Conc Unit | Biological Replicate ID | Relative Cell Count | Normalized Growth Rate Inhibition Value | Nominal Division Rate |
|---|---|---|---|---|---|---|---|---|---|---|---|---|
| HCC3153 | TNBC | Basal A | Fascaplysin | CDK4 | CDK | 33.3 | uM | 7467.084 | 0.0038 | -0.9722 | 1.3029 | |
| HCC38 | TNBC | Basal B | Fascaplysin | CDK4 | CDK | 0.0000853 | uM | 7468.085 | 1.0205 | 1.0284 | 1.4385 | |
| HCC38 | TNBC | Basal B | Fascaplysin | CDK4 | CDK | 0.000427 | uM | 7468.085 | 0.9780 | 0.9693 | 1.4385 | |
| HCC38 | TNBC | Basal B | Fascaplysin | CDK4 | CDK | 0.00213 | uM | 7468.085 | 0.9298 | 0.9013 | 1.4385 | |
| HCC38 | TNBC | Basal B | Fascaplysin | CDK4 | CDK | 0.0107 | uM | 7468.085 | 0.9673 | 0.9543 | 1.4385 | |
| HCC38 | TNBC | Basal B | Fascaplysin | CDK4 | CDK | 0.0533 | uM | 7468.085 | 0.9230 | 0.8917 | 1.4385 | |
| HCC38 | TNBC | Basal B | Fascaplysin | CDK4 | CDK | 0.267 | uM | 7468.085 | 0.6621 | 0.5016 | 1.4385 | |
| HCC38 | TNBC | Basal B | Fascaplysin | CDK4 | CDK | 1.33 | uM | 7468.085 | 0.0227 | -0.8562 | 1.4385 | |
| HCC38 | TNBC | Basal B | Fascaplysin | CDK4 | CDK | 6.67 | uM | 7468.085 | 0.0071 | -0.9359 | 1.4385 | |
| HCC38 | TNBC | Basal B | Fascaplysin | CDK4 | CDK | 33.3 | uM | 7468.085 | 0.0037 | -0.9590 | 1.4385 | |
| HCC38 | TNBC | Basal B | Fascaplysin | CDK4 | CDK | 0.0000853 | uM | 7469.084 | 0.8929 | 0.8919 | 2.0377 | |
| HCC38 | TNBC | Basal B | Fascaplysin | CDK4 | CDK | 0.000427 | uM | 7469.084 | 0.9280 | 0.9280 | 2.0377 | |
| HCC38 | TNBC | Basal B | Fascaplysin | CDK4 | CDK | 0.00213 | uM | 7469.084 | 0.9512 | 0.9515 | 2.0377 | |
| HCC38 | TNBC | Basal B | Fascaplysin | CDK4 | CDK | 0.0107 | uM | 7469.084 | 0.9150 | 0.9147 | 2.0377 | |
| HCC38 | TNBC | Basal B | Fascaplysin | CDK4 | CDK | 0.0533 | uM | 7469.084 | 0.8738 | 0.8719 | 2.0377 | |
| HCC38 | TNBC | Basal B | Fascaplysin | CDK4 | CDK | 0.267 | uM | 7469.084 | 0.6726 | 0.6462 | 2.0377 | |
| HCC38 | TNBC | Basal B | Fascaplysin | CDK4 | CDK | 1.33 | uM | 7469.084 | 0.0262 | -0.6651 | 2.0377 | |
| HCC38 | TNBC | Basal B | Fascaplysin | CDK4 | CDK | 6.67 | uM | 7469.084 | 0.0094 | -0.7980 | 2.0377 | |
| HCC38 | TNBC | Basal B | Fascaplysin | CDK4 | CDK | 33.3 | uM | 7469.084 | 0.0037 | -0.8718 | 2.0377 | |
| HCC70 | TNBC | Basal A | Fascaplysin | CDK4 | CDK | 0.0000853 | uM | 7470.085 | 0.9688 | 0.9368 | 0.9880 | |
| HCC70 | TNBC | Basal A | Fascaplysin | CDK4 | CDK | 0.000427 | uM | 7470.085 | 0.9506 | 0.9000 | 0.9880 | |
| HCC70 | TNBC | Basal A | Fascaplysin | CDK4 | CDK | 0.00213 | uM | 7470.085 | 0.8960 | 0.7897 | 0.9880 | |
| HCC70 | TNBC | Basal A | Fascaplysin | CDK4 | CDK | 0.0107 | uM | 7470.085 | 0.9413 | 0.8812 | 0.9880 | |
| HCC70 | TNBC | Basal A | Fascaplysin | CDK4 | CDK | 0.0533 | uM | 7470.085 | 0.8811 | 0.7594 | 0.9880 | |
| HCC70 | TNBC | Basal A | Fascaplysin | CDK4 | CDK | 0.267 | uM | 7470.085 | 0.5201 | 0.0319 | 0.9880 |