Growth rate-corrected (GR) dose-response metrics across a panel of 71 breast cancer cell lines treated with a library of small molecule and antibody perturbagens. Dataset 1 of 4: Relative cell counts and normalized growth rate inhibition values across technical replicates. - Dataset (ID:20268)
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| Cell | Clinical Subtype | Transcriptional Subtype | Small Molecule | Antibody | Perturbagen Target | Perturbagen Class | Perturbagen Concentration | Perturbagen Conc Unit | Biological Replicate ID | Relative Cell Count | Normalized Growth Rate Inhibition Value | Nominal Division Rate |
|---|---|---|---|---|---|---|---|---|---|---|---|---|
| HCC1806 | TNBC | Basal A | Fascaplysin | CDK4 | CDK | 6.67 | uM | 7450.084 | 0.0169 | -0.6491 | 2.3432 | |
| HCC1806 | TNBC | Basal A | Fascaplysin | CDK4 | CDK | 33.3 | uM | 7450.084 | 0.0123 | -0.6942 | 2.3432 | |
| HCC1806 | TNBC | Basal A | Fascaplysin | CDK4 | CDK | 0.0000853 | uM | 7451.085 | 0.9603 | 0.9626 | 2.1458 | |
| HCC1806 | TNBC | Basal A | Fascaplysin | CDK4 | CDK | 0.000427 | uM | 7451.085 | 0.9744 | 0.9760 | 2.1458 | |
| HCC1806 | TNBC | Basal A | Fascaplysin | CDK4 | CDK | 0.00213 | uM | 7451.085 | 0.9117 | 0.9156 | 2.1458 | |
| HCC1806 | TNBC | Basal A | Fascaplysin | CDK4 | CDK | 0.0107 | uM | 7451.085 | 0.9358 | 0.9391 | 2.1458 | |
| HCC1806 | TNBC | Basal A | Fascaplysin | CDK4 | CDK | 0.0533 | uM | 7451.085 | 0.9147 | 0.9186 | 2.1458 | |
| HCC1806 | TNBC | Basal A | Fascaplysin | CDK4 | CDK | 0.267 | uM | 7451.085 | 0.5566 | 0.5222 | 2.1458 | |
| HCC1806 | TNBC | Basal A | Fascaplysin | CDK4 | CDK | 1.33 | uM | 7451.085 | 0.0126 | -0.7398 | 2.1458 | |
| HCC1806 | TNBC | Basal A | Fascaplysin | CDK4 | CDK | 6.67 | uM | 7451.085 | 0.0098 | -0.7678 | 2.1458 | |
| HCC1806 | TNBC | Basal A | Fascaplysin | CDK4 | CDK | 33.3 | uM | 7451.085 | 0.0045 | -0.8387 | 2.1458 | |
| HCC1937 | TNBC | Basal A | Fascaplysin | CDK4 | CDK | 0.0000853 | uM | 7452.084 | 0.9750 | 0.9700 | 1.6800 | |
| HCC1937 | TNBC | Basal A | Fascaplysin | CDK4 | CDK | 0.000427 | uM | 7452.084 | 0.9783 | 0.9740 | 1.6800 | |
| HCC1937 | TNBC | Basal A | Fascaplysin | CDK4 | CDK | 0.00213 | uM | 7452.084 | 0.9590 | 0.9507 | 1.6800 | |
| HCC1937 | TNBC | Basal A | Fascaplysin | CDK4 | CDK | 0.0107 | uM | 7452.084 | 1.0190 | 1.0225 | 1.6800 | |
| HCC1937 | TNBC | Basal A | Fascaplysin | CDK4 | CDK | 0.0533 | uM | 7452.084 | 0.9750 | 0.9700 | 1.6800 | |
| HCC1937 | TNBC | Basal A | Fascaplysin | CDK4 | CDK | 0.267 | uM | 7452.084 | 0.8029 | 0.7550 | 1.6800 | |
| HCC1937 | TNBC | Basal A | Fascaplysin | CDK4 | CDK | 1.33 | uM | 7452.084 | 0.0319 | -0.7429 | 1.6800 | |
| HCC1937 | TNBC | Basal A | Fascaplysin | CDK4 | CDK | 6.67 | uM | 7452.084 | 0.0099 | -0.8721 | 1.6800 | |
| HCC1937 | TNBC | Basal A | Fascaplysin | CDK4 | CDK | 33.3 | uM | 7452.084 | 0.0057 | -0.9076 | 1.6800 | |
| HCC1937 | TNBC | Basal A | Fascaplysin | CDK4 | CDK | 0.0000853 | uM | 7453.084 | 1.0023 | 1.0029 | 1.5592 | |
| HCC1937 | TNBC | Basal A | Fascaplysin | CDK4 | CDK | 0.000427 | uM | 7453.084 | 1.0045 | 1.0058 | 1.5592 | |
| HCC1937 | TNBC | Basal A | Fascaplysin | CDK4 | CDK | 0.00213 | uM | 7453.084 | 0.9663 | 0.9565 | 1.5592 | |
| HCC1937 | TNBC | Basal A | Fascaplysin | CDK4 | CDK | 0.0107 | uM | 7453.084 | 0.9725 | 0.9646 | 1.5592 | |
| HCC1937 | TNBC | Basal A | Fascaplysin | CDK4 | CDK | 0.0533 | uM | 7453.084 | 0.9768 | 0.9701 | 1.5592 |