Growth rate-corrected (GR) dose-response metrics across a panel of 71 breast cancer cell lines treated with a library of small molecule and antibody perturbagens. Dataset 1 of 4: Relative cell counts and normalized growth rate inhibition values across technical replicates. - Dataset (ID:20268)
Download: Excel (XLSX), Comma-separated (CSV)
| Cell | Clinical Subtype | Transcriptional Subtype | Small Molecule | Antibody | Perturbagen Target | Perturbagen Class | Perturbagen Concentration | Perturbagen Conc Unit | Biological Replicate ID | Relative Cell Count | Normalized Growth Rate Inhibition Value | Nominal Division Rate |
|---|---|---|---|---|---|---|---|---|---|---|---|---|
| HCC3153 | TNBC | Basal A | Gefitinib | EGFR | ErbB | 0.267 | uM | 7853.016 | 0.9754 | 0.9694 | 1.6178 | |
| HCC3153 | TNBC | Basal A | Gefitinib | EGFR | ErbB | 1.33 | uM | 7853.016 | 0.9887 | 0.9860 | 1.6178 | |
| HCC3153 | TNBC | Basal A | Gefitinib | EGFR | ErbB | 6.67 | uM | 7853.016 | 0.9142 | 0.8921 | 1.6178 | |
| HCC3153 | TNBC | Basal A | Gefitinib | EGFR | ErbB | 33.3 | uM | 7853.016 | 0.7044 | 0.6105 | 1.6178 | |
| HCC38 | TNBC | Basal B | Gefitinib | EGFR | ErbB | 0.0000853 | uM | 7854.016 | 1.0829 | 1.1835 | 0.9074 | |
| HCC38 | TNBC | Basal B | Gefitinib | EGFR | ErbB | 0.000427 | uM | 7854.016 | 0.9889 | 0.9756 | 0.9074 | |
| HCC38 | TNBC | Basal B | Gefitinib | EGFR | ErbB | 0.00213 | uM | 7854.016 | 0.9566 | 0.9045 | 0.9074 | |
| HCC38 | TNBC | Basal B | Gefitinib | EGFR | ErbB | 0.0107 | uM | 7854.016 | 1.1287 | 1.2854 | 0.9074 | |
| HCC38 | TNBC | Basal B | Gefitinib | EGFR | ErbB | 0.0533 | uM | 7854.016 | 1.0131 | 1.0289 | 0.9074 | |
| HCC38 | TNBC | Basal B | Gefitinib | EGFR | ErbB | 0.267 | uM | 7854.016 | 1.0301 | 1.0663 | 0.9074 | |
| HCC38 | TNBC | Basal B | Gefitinib | EGFR | ErbB | 1.33 | uM | 7854.016 | 1.1735 | 1.3856 | 0.9074 | |
| HCC38 | TNBC | Basal B | Gefitinib | EGFR | ErbB | 6.67 | uM | 7854.016 | 1.0908 | 1.2011 | 0.9074 | |
| HCC38 | TNBC | Basal B | Gefitinib | EGFR | ErbB | 33.3 | uM | 7854.016 | 0.4883 | -0.0924 | 0.9074 | |
| HCC38 | TNBC | Basal B | Gefitinib | EGFR | ErbB | 0.0000853 | uM | 9028.016 | 0.9942 | 0.9906 | 1.2348 | |
| HCC38 | TNBC | Basal B | Gefitinib | EGFR | ErbB | 0.000427 | uM | 9028.016 | 0.9382 | 0.8993 | 1.2348 | |
| HCC38 | TNBC | Basal B | Gefitinib | EGFR | ErbB | 0.00213 | uM | 9028.016 | 0.9181 | 0.8664 | 1.2348 | |
| HCC38 | TNBC | Basal B | Gefitinib | EGFR | ErbB | 0.0107 | uM | 9028.016 | 1.0065 | 1.0105 | 1.2348 | |
| HCC38 | TNBC | Basal B | Gefitinib | EGFR | ErbB | 0.0533 | uM | 9028.016 | 1.0404 | 1.0653 | 1.2348 | |
| HCC38 | TNBC | Basal B | Gefitinib | EGFR | ErbB | 0.267 | uM | 9028.016 | 1.0049 | 1.0079 | 1.2348 | |
| HCC38 | TNBC | Basal B | Gefitinib | EGFR | ErbB | 1.33 | uM | 9028.016 | 1.0374 | 1.0603 | 1.2348 | |
| HCC38 | TNBC | Basal B | Gefitinib | EGFR | ErbB | 6.67 | uM | 9028.016 | 1.0097 | 1.0157 | 1.2348 | |
| HCC38 | TNBC | Basal B | Gefitinib | EGFR | ErbB | 33.3 | uM | 9028.016 | 0.5718 | 0.2718 | 1.2348 | |
| HCC38 | TNBC | Basal B | Gefitinib | EGFR | ErbB | 0.0000853 | uM | 9453.019 | 1.0229 | 1.0399 | 1.1486 | |
| HCC38 | TNBC | Basal B | Gefitinib | EGFR | ErbB | 0.000427 | uM | 9453.019 | 0.9586 | 0.9278 | 1.1486 | |
| HCC38 | TNBC | Basal B | Gefitinib | EGFR | ErbB | 0.00213 | uM | 9453.019 | 0.9608 | 0.9316 | 1.1486 |