Growth rate-corrected (GR) dose-response metrics across a panel of 71 breast cancer cell lines treated with a library of small molecule and antibody perturbagens. Dataset 1 of 4: Relative cell counts and normalized growth rate inhibition values across technical replicates. - Dataset (ID:20268)
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| Cell | Clinical Subtype | Transcriptional Subtype | Small Molecule | Antibody | Perturbagen Target | Perturbagen Class | Perturbagen Concentration | Perturbagen Conc Unit | Biological Replicate ID | Relative Cell Count | Normalized Growth Rate Inhibition Value | Nominal Division Rate |
|---|---|---|---|---|---|---|---|---|---|---|---|---|
| SUM1315MO2 | TNBC | Basal B | Everolimus | MTOR | MTOR | 0.0213 | uM | 12428.164 | 0.8259 | 0.5897 | 0.8332 | |
| SUM1315MO2 | TNBC | Basal B | Everolimus | MTOR | MTOR | 0.107 | uM | 12428.164 | 0.7937 | 0.5155 | 0.8332 | |
| SUM1315MO2 | TNBC | Basal B | Everolimus | MTOR | MTOR | 0.533 | uM | 12428.164 | 0.7848 | 0.4954 | 0.8332 | |
| SUM1315MO2 | TNBC | Basal B | Everolimus | MTOR | MTOR | 2.67 | uM | 12428.164 | 0.7435 | 0.4014 | 0.8332 | |
| SUM1315MO2 | TNBC | Basal B | Everolimus | MTOR | MTOR | 13.3 | uM | 12428.164 | 0.6800 | 0.2589 | 0.8332 | |
| SUM1315MO2 | TNBC | Basal B | Everolimus | MTOR | MTOR | 66.7 | uM | 12428.164 | 0.0124 | -0.9897 | 0.8332 | |
| SUM149PT | TNBC | Basal B | Everolimus | MTOR | MTOR | 0.000171 | uM | 11937.164 | 0.9455 | 0.9568 | 2.5679 | |
| SUM149PT | TNBC | Basal B | Everolimus | MTOR | MTOR | 0.000853 | uM | 11937.164 | 0.9368 | 0.9498 | 2.5679 | |
| SUM149PT | TNBC | Basal B | Everolimus | MTOR | MTOR | 0.00427 | uM | 11937.164 | 0.9509 | 0.9612 | 2.5679 | |
| SUM149PT | TNBC | Basal B | Everolimus | MTOR | MTOR | 0.0213 | uM | 11937.164 | 0.8784 | 0.9015 | 2.5679 | |
| SUM149PT | TNBC | Basal B | Everolimus | MTOR | MTOR | 0.107 | uM | 11937.164 | 0.7202 | 0.7600 | 2.5679 | |
| SUM149PT | TNBC | Basal B | Everolimus | MTOR | MTOR | 0.533 | uM | 11937.164 | 0.6772 | 0.7183 | 2.5679 | |
| SUM149PT | TNBC | Basal B | Everolimus | MTOR | MTOR | 2.67 | uM | 11937.164 | 0.6760 | 0.7171 | 2.5679 | |
| SUM149PT | TNBC | Basal B | Everolimus | MTOR | MTOR | 13.3 | uM | 11937.164 | 0.5597 | 0.5954 | 2.5679 | |
| SUM149PT | TNBC | Basal B | Everolimus | MTOR | MTOR | 66.7 | uM | 11937.164 | 0.0099 | -0.6684 | 2.5679 | |
| SUM159PT | TNBC | Basal B | Everolimus | MTOR | MTOR | 0.000171 | uM | 11057.156 | 1.2281 | 1.1190 | 3.5568 | |
| SUM159PT | TNBC | Basal B | Everolimus | MTOR | MTOR | 0.000853 | uM | 11057.156 | 1.0185 | 1.0104 | 3.5568 | |
| SUM159PT | TNBC | Basal B | Everolimus | MTOR | MTOR | 0.00427 | uM | 11057.156 | 0.8824 | 0.9309 | 3.5568 | |
| SUM159PT | TNBC | Basal B | Everolimus | MTOR | MTOR | 0.0213 | uM | 11057.156 | 0.6684 | 0.7858 | 3.5568 | |
| SUM159PT | TNBC | Basal B | Everolimus | MTOR | MTOR | 0.107 | uM | 11057.156 | 0.4923 | 0.6387 | 3.5568 | |
| SUM159PT | TNBC | Basal B | Everolimus | MTOR | MTOR | 0.533 | uM | 11057.156 | 0.5454 | 0.6866 | 3.5568 | |
| SUM159PT | TNBC | Basal B | Everolimus | MTOR | MTOR | 2.67 | uM | 11057.156 | 0.5111 | 0.6560 | 3.5568 | |
| SUM159PT | TNBC | Basal B | Everolimus | MTOR | MTOR | 13.3 | uM | 11057.156 | 0.4464 | 0.5942 | 3.5568 | |
| SUM159PT | TNBC | Basal B | Everolimus | MTOR | MTOR | 66.7 | uM | 11057.156 | 0.0005 | -0.7626 | 3.5568 | |
| SUM185PE | TNBC | Luminal | Everolimus | MTOR | MTOR | 0.000171 | uM | 12269.164 | 1.3242 | 3.0069 | 0.4042 |