Growth rate-corrected (GR) dose-response metrics across a panel of 71 breast cancer cell lines treated with a library of small molecule and antibody perturbagens. Dataset 1 of 4: Relative cell counts and normalized growth rate inhibition values across technical replicates. - Dataset (ID:20268)
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| Cell | Clinical Subtype | Transcriptional Subtype | Small Molecule | Antibody | Perturbagen Target | Perturbagen Class | Perturbagen Concentration | Perturbagen Conc Unit | Biological Replicate ID | Relative Cell Count | Normalized Growth Rate Inhibition Value | Nominal Division Rate |
|---|---|---|---|---|---|---|---|---|---|---|---|---|
| MX1 | Unknown | Unknown | Everolimus | MTOR | MTOR | 0.533 | uM | 10874.156 | 0.8165 | 0.4939 | 0.6949 | |
| MX1 | Unknown | Unknown | Everolimus | MTOR | MTOR | 2.67 | uM | 10874.156 | 0.7843 | 0.4099 | 0.6949 | |
| MX1 | Unknown | Unknown | Everolimus | MTOR | MTOR | 13.3 | uM | 10874.156 | 0.6882 | 0.1682 | 0.6949 | |
| MX1 | Unknown | Unknown | Everolimus | MTOR | MTOR | 66.7 | uM | 10874.156 | 0.0122 | -0.9965 | 0.6949 | |
| SK-BR-3 | HER2amp | Luminal | Everolimus | MTOR | MTOR | 0.000171 | uM | 11851.156 | 1.1585 | 1.3013 | 1.0483 | |
| SK-BR-3 | HER2amp | Luminal | Everolimus | MTOR | MTOR | 0.000853 | uM | 11851.156 | 1.1195 | 1.2273 | 1.0483 | |
| SK-BR-3 | HER2amp | Luminal | Everolimus | MTOR | MTOR | 0.00427 | uM | 11851.156 | 0.9524 | 0.9092 | 1.0483 | |
| SK-BR-3 | HER2amp | Luminal | Everolimus | MTOR | MTOR | 0.0213 | uM | 11851.156 | 0.7618 | 0.5428 | 1.0483 | |
| SK-BR-3 | HER2amp | Luminal | Everolimus | MTOR | MTOR | 0.107 | uM | 11851.156 | 0.6001 | 0.2288 | 1.0483 | |
| SK-BR-3 | HER2amp | Luminal | Everolimus | MTOR | MTOR | 0.533 | uM | 11851.156 | 0.6195 | 0.2667 | 1.0483 | |
| SK-BR-3 | HER2amp | Luminal | Everolimus | MTOR | MTOR | 2.67 | uM | 11851.156 | 0.6231 | 0.2737 | 1.0483 | |
| SK-BR-3 | HER2amp | Luminal | Everolimus | MTOR | MTOR | 13.3 | uM | 11851.156 | 0.5708 | 0.1716 | 1.0483 | |
| SK-BR-3 | HER2amp | Luminal | Everolimus | MTOR | MTOR | 66.7 | uM | 11851.156 | 0.1895 | -0.5908 | 1.0483 | |
| SUM1315MO2 | TNBC | Basal B | Everolimus | MTOR | MTOR | 0.000171 | uM | 10875.156 | 1.0008 | 1.0034 | 0.4392 | |
| SUM1315MO2 | TNBC | Basal B | Everolimus | MTOR | MTOR | 0.000853 | uM | 10875.156 | 0.9970 | 0.9863 | 0.4392 | |
| SUM1315MO2 | TNBC | Basal B | Everolimus | MTOR | MTOR | 0.00427 | uM | 10875.156 | 0.8873 | 0.5232 | 0.4392 | |
| SUM1315MO2 | TNBC | Basal B | Everolimus | MTOR | MTOR | 0.0213 | uM | 10875.156 | 0.9304 | 0.6968 | 0.4392 | |
| SUM1315MO2 | TNBC | Basal B | Everolimus | MTOR | MTOR | 0.107 | uM | 10875.156 | 0.8011 | 0.2071 | 0.4392 | |
| SUM1315MO2 | TNBC | Basal B | Everolimus | MTOR | MTOR | 0.533 | uM | 10875.156 | 0.8290 | 0.3048 | 0.4392 | |
| SUM1315MO2 | TNBC | Basal B | Everolimus | MTOR | MTOR | 2.67 | uM | 10875.156 | 0.7949 | 0.1858 | 0.4392 | |
| SUM1315MO2 | TNBC | Basal B | Everolimus | MTOR | MTOR | 13.3 | uM | 10875.156 | 0.7405 | 0.0091 | 0.4392 | |
| SUM1315MO2 | TNBC | Basal B | Everolimus | MTOR | MTOR | 66.7 | uM | 10875.156 | 0.0078 | -1.0000 | 0.4392 | |
| SUM1315MO2 | TNBC | Basal B | Everolimus | MTOR | MTOR | 0.000171 | uM | 12428.164 | 1.0130 | 1.0312 | 0.8332 | |
| SUM1315MO2 | TNBC | Basal B | Everolimus | MTOR | MTOR | 0.000853 | uM | 12428.164 | 0.9568 | 0.8967 | 0.8332 | |
| SUM1315MO2 | TNBC | Basal B | Everolimus | MTOR | MTOR | 0.00427 | uM | 12428.164 | 0.9123 | 0.7913 | 0.8332 |