Multiplexed imaging of protein levels and protein phosphorylation states in the MCF 10A breast cell line treated with nine kinase inhibitors - Dataset (ID:20266)

Proteins Studied

  • 25 Proteins
LINCS ID Name HMS LINCS ID UniProt ID Alternative Names Provider Mutation Phosphlorylation State Domain Protein Description
201295 p21 201295 P38936
Cyclin-dependent kinase inhibitor 1; CDK-interacting protein 1; Melanoma differentiation-associated protein 6; MDA-6
201297 Rb (pS807; pS811) 201297 P06400 pS807; pS811
201299 S6 (pS240; pS244) 201299 P62753 pS240; pS244
201303 ERK-1 (pT202; pY204) 201303 P27361 pT202; pY204
201304 ERK-2 (pT185; pY187) 201304 P28482 pT185; pY187
201337 ERK-1 (pT202) 201337 P27361 pT202
201338 ERK-2 (pT185) 201338 P28482 pT185
201344 p27Kip1 201344 P46527
Cyclin-dependent kinase inhibitor 1B; Cyclin-dependent kinase inhibitor p27
201350 FOXO3a 201350 O43524
Forkhead box protein O3; AF6q21 protein; Forkhead in rhabdomyosarcoma-like 1
201362 p27Kip1 (pT187) 201362 P46527 pT187
201363 Cyclin-A1 201363 P78396
201364 Cyclin-A2 201364 P20248
Cyclin-A
201381 S6K-alpha-1 (pS380) 201381 Q15418 pS380
201384 Cyclin-B1 201384 P14635
G2/mitotic-specific cyclin-B1
201385 FoxM1 201385 Q08050
Forkhead box protein M1; Forkhead-related protein FKHL16; Hepatocyte nuclear factor 3 forkhead homolog 11; HFH-11; HNF-3/fork-head homolog 11; M-phase phosphoprotein 2; MPM-2 reactive phosphoprotein 2; Transcription factor Trident; Winged-helix factor from INS-1 cells
201386 CDK1 (pY15) 201386 P06493 pY15
201387 CDK2 (pY15) 201387 P24941 pY15
201388 p27Kip1 (pS10) 201388 P46527 pS10
201389 p57Kip2 201389 P49918
Cyclin-dependent kinase inhibitor 1C; Cyclin-dependent kinase inhibitor p57
201390 Akt-1 (pS473) 201390 P31749 pS473
201391 p57Kip2 (pT310) 201391 P49918 pT310
201392 Survivin 201392 O15392
Baculoviral IAP repeat-containing protein 5; Apoptosis inhibitor 4; Apoptosis inhibitor survivin
201396 4EBP1 (pT37; pT46) 201396 Q13541 pT37; pT46
201397 4EBP1 (pT37) 201397 Q13541 pT37
201398 4EBP1 (pT46) 201398 Q13541 pT46
  • 25 Proteins