Breast Cancer Cell Density: Imaging assay of the density- and context-dependence of small molecule perturbagen response in breast cancer cell lines. Dataset 2 of 3: Mean cell count and mean normalized growth rate inhibition values across all replicates. - Dataset (ID:20257)
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Cell | Small Molecule | Small Mol Concentration | Small Mol Conc Unit | Replicate | Seeding Density | Mean Total Cell Count Before Treatment | Mean Total Cell Count After Treatment | Mean Total Control Cell Count | Mean Relative Cell Count | Mean Normalized Growth Rate Inhibition Value |
---|---|---|---|---|---|---|---|---|---|---|
MCF 10A | PLX-4720 | 3.1623 | uM | 2 | 5000.00 | 3410.67 | 8344.67 | 6794.33 | 1.2289 | 1.4658 |
MCF 10A | PLX-4720 | 10 | uM | 2 | 5000.00 | 3410.67 | 8199.67 | 6794.33 | 1.2087 | 1.4290 |
MCF 10A | PLX-4720 | 19.9526 | uM | 2 | 5000.00 | 3410.67 | 8749.67 | 6794.33 | 1.2912 | 1.6020 |
MCF 10A | NVP-TAE684 | 0.0016596 | uM | 2 | 5000.00 | 3410.67 | 6712.67 | 6794.33 | 0.9914 | 0.9930 |
MCF 10A | NVP-TAE684 | 0.0033113 | uM | 2 | 5000.00 | 3410.67 | 6798.00 | 6794.33 | 1.0016 | 1.0068 |
MCF 10A | NVP-TAE684 | 0.01 | uM | 2 | 5000.00 | 3410.67 | 6734.00 | 6794.33 | 0.9945 | 0.9996 |
MCF 10A | NVP-TAE684 | 0.031623 | uM | 2 | 5000.00 | 3410.67 | 6876.33 | 6794.33 | 1.0146 | 1.0373 |
MCF 10A | NVP-TAE684 | 0.1 | uM | 2 | 5000.00 | 3410.67 | 5500.33 | 6794.33 | 0.8130 | 0.6317 |
MCF 10A | NVP-TAE684 | 0.31623 | uM | 2 | 5000.00 | 3410.67 | 4910.67 | 6794.33 | 0.7246 | 0.4490 |
MCF 10A | NVP-TAE684 | 1 | uM | 2 | 5000.00 | 3410.67 | 3542.00 | 6794.33 | 0.5238 | 0.0450 |
MCF 10A | NVP-TAE684 | 3.1623 | uM | 2 | 5000.00 | 3410.67 | 2119.33 | 6794.33 | 0.3117 | -0.3828 |
MCF 10A | NVP-TAE684 | 10 | uM | 2 | 5000.00 | 3410.67 | 1365.33 | 6794.33 | 0.2012 | -0.6027 |
MCF 10A | Palbociclib | 0.0033113 | uM | 2 | 5000.00 | 3410.67 | 5631.67 | 5991.17 | 0.9386 | 0.8477 |
MCF 10A | Palbociclib | 0.01 | uM | 2 | 5000.00 | 3410.67 | 5202.67 | 5991.17 | 0.8701 | 0.6933 |
MCF 10A | Palbociclib | 0.031623 | uM | 2 | 5000.00 | 3410.67 | 5269.67 | 5991.17 | 0.8784 | 0.7010 |
MCF 10A | Palbociclib | 0.1 | uM | 2 | 5000.00 | 3410.67 | 4008.33 | 5991.17 | 0.6719 | 0.2317 |
MCF 10A | Palbociclib | 0.31623 | uM | 2 | 5000.00 | 3410.67 | 3267.00 | 5991.17 | 0.5476 | -0.0404 |
MCF 10A | Palbociclib | 1 | uM | 2 | 5000.00 | 3410.67 | 2361.67 | 5991.17 | 0.3930 | -0.3664 |
MCF 10A | Palbociclib | 3.1623 | uM | 2 | 5000.00 | 3410.67 | 2563.00 | 5991.17 | 0.4287 | -0.2970 |
MCF 10A | Palbociclib | 10 | uM | 2 | 5000.00 | 3410.67 | 2546.67 | 5991.17 | 0.4261 | -0.3021 |
MCF 10A | Palbociclib | 19.9526 | uM | 2 | 5000.00 | 3410.67 | 2750.33 | 5991.17 | 0.4577 | -0.2369 |
MDA-MB-231 | Omipalisib | 0.0016596 | uM | 2 | 156.25 | 73.46 | 183.67 | 178.33 | 1.0374 | 1.0533 |
MDA-MB-231 | Omipalisib | 0.0033113 | uM | 2 | 156.25 | 73.46 | 222.67 | 178.33 | 1.2365 | 1.3437 |
MDA-MB-231 | Omipalisib | 0.01 | uM | 2 | 156.25 | 73.46 | 204.00 | 178.33 | 1.1975 | 1.3838 |
MDA-MB-231 | Omipalisib | 0.031623 | uM | 2 | 156.25 | 73.46 | 139.33 | 178.33 | 0.7921 | 0.6750 |