Breast Cancer Cell Density: Imaging assay of the density- and context-dependence of small molecule perturbagen response in breast cancer cell lines. Dataset 2 of 3: Mean cell count and mean normalized growth rate inhibition values across all replicates. - Dataset (ID:20257)
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Cell | Small Molecule | Small Mol Concentration | Small Mol Conc Unit | Replicate | Seeding Density | Mean Total Cell Count Before Treatment | Mean Total Cell Count After Treatment | Mean Total Control Cell Count | Mean Relative Cell Count | Mean Normalized Growth Rate Inhibition Value |
---|---|---|---|---|---|---|---|---|---|---|
MCF 10A | Nilotinib | 3.1623 | uM | 2 | 625.00 | 277.50 | 4499.67 | 4163.75 | 1.0886 | 1.0383 |
MCF 10A | Nilotinib | 10 | uM | 2 | 625.00 | 277.50 | 1471.33 | 4163.75 | 0.3466 | 0.5030 |
MCF 10A | Nilotinib | 19.9526 | uM | 2 | 625.00 | 277.50 | 343.33 | 4163.75 | 0.0818 | 0.0506 |
MCF 10A | PLX-4720 | 0.0033113 | uM | 2 | 625.00 | 277.50 | 4076.67 | 4163.75 | 0.9827 | 0.9897 |
MCF 10A | PLX-4720 | 0.01 | uM | 2 | 625.00 | 277.50 | 3976.00 | 4163.75 | 0.9539 | 0.9756 |
MCF 10A | PLX-4720 | 0.031623 | uM | 2 | 625.00 | 277.50 | 4840.33 | 4163.75 | 1.1745 | 1.0811 |
MCF 10A | PLX-4720 | 0.1 | uM | 2 | 625.00 | 277.50 | 5016.33 | 4163.75 | 1.2072 | 1.0954 |
MCF 10A | PLX-4720 | 0.31623 | uM | 2 | 625.00 | 277.50 | 4441.67 | 4163.75 | 1.0724 | 1.0340 |
MCF 10A | PLX-4720 | 1 | uM | 2 | 625.00 | 277.50 | 4118.33 | 4163.75 | 0.9968 | 0.9972 |
MCF 10A | PLX-4720 | 3.1623 | uM | 2 | 625.00 | 277.50 | 4653.00 | 4163.75 | 1.1221 | 1.0589 |
MCF 10A | PLX-4720 | 10 | uM | 2 | 625.00 | 277.50 | 3290.33 | 4163.75 | 0.7834 | 0.8737 |
MCF 10A | PLX-4720 | 19.9526 | uM | 2 | 625.00 | 277.50 | 1586.00 | 4163.75 | 0.3798 | 0.5546 |
MCF 10A | NVP-TAE684 | 0.0016596 | uM | 2 | 625.00 | 277.50 | 4234.67 | 4163.75 | 1.0114 | 0.9987 |
MCF 10A | NVP-TAE684 | 0.0033113 | uM | 2 | 625.00 | 277.50 | 4421.00 | 4163.75 | 1.0613 | 1.0304 |
MCF 10A | NVP-TAE684 | 0.01 | uM | 2 | 625.00 | 277.50 | 4528.00 | 4163.75 | 1.0994 | 1.0449 |
MCF 10A | NVP-TAE684 | 0.031623 | uM | 2 | 625.00 | 277.50 | 3771.67 | 4163.75 | 0.9071 | 0.9508 |
MCF 10A | NVP-TAE684 | 0.1 | uM | 2 | 625.00 | 277.50 | 2975.67 | 4163.75 | 0.7145 | 0.8348 |
MCF 10A | NVP-TAE684 | 0.31623 | uM | 2 | 625.00 | 277.50 | 1830.33 | 4163.75 | 0.4358 | 0.6129 |
MCF 10A | NVP-TAE684 | 1 | uM | 2 | 625.00 | 277.50 | 804.67 | 4163.75 | 0.1935 | 0.3128 |
MCF 10A | NVP-TAE684 | 3.1623 | uM | 2 | 625.00 | 277.50 | 265.00 | 4163.75 | 0.0635 | -0.0140 |
MCF 10A | NVP-TAE684 | 10 | uM | 2 | 625.00 | 277.50 | 143.33 | 4163.75 | 0.0343 | -0.1686 |
MCF 10A | Palbociclib | 0.0033113 | uM | 2 | 625.00 | 277.50 | 2779.67 | 3384.25 | 0.8507 | 0.8780 |
MCF 10A | Palbociclib | 0.01 | uM | 2 | 625.00 | 277.50 | 2690.67 | 3384.25 | 0.8167 | 0.8747 |
MCF 10A | Palbociclib | 0.031623 | uM | 2 | 625.00 | 277.50 | 1769.67 | 3384.25 | 0.5306 | 0.6734 |
MCF 10A | Palbociclib | 0.1 | uM | 2 | 625.00 | 277.50 | 2602.67 | 3384.25 | 0.7637 | 0.8431 |