Breast Cancer Cell Density: Imaging assay of the density- and context-dependence of small molecule perturbagen response in breast cancer cell lines. Dataset 2 of 3: Mean cell count and mean normalized growth rate inhibition values across all replicates. - Dataset (ID:20257)
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Cell | Small Molecule | Small Mol Concentration | Small Mol Conc Unit | Replicate | Seeding Density | Mean Total Cell Count Before Treatment | Mean Total Cell Count After Treatment | Mean Total Control Cell Count | Mean Relative Cell Count | Mean Normalized Growth Rate Inhibition Value |
---|---|---|---|---|---|---|---|---|---|---|
MCF 10A | Palbociclib | 0.31623 | uM | 2 | 625.00 | 277.50 | 1128.00 | 3384.25 | 0.3387 | 0.4705 |
MCF 10A | Palbociclib | 1 | uM | 2 | 625.00 | 277.50 | 606.67 | 3384.25 | 0.1800 | 0.2336 |
MCF 10A | Palbociclib | 3.1623 | uM | 2 | 625.00 | 277.50 | 421.00 | 3384.25 | 0.1228 | 0.1120 |
MCF 10A | Palbociclib | 10 | uM | 2 | 625.00 | 277.50 | 281.67 | 3384.25 | 0.0845 | 0.0021 |
MCF 10A | Palbociclib | 19.9526 | uM | 2 | 625.00 | 277.50 | 309.83 | 3384.25 | 0.0907 | 0.0110 |
MCF 10A | Omipalisib | 0.0016596 | uM | 2 | 1250.00 | 585.71 | 2607.00 | 6891.50 | 0.3781 | 0.5210 |
MCF 10A | Omipalisib | 0.0033113 | uM | 2 | 1250.00 | 585.71 | 2317.33 | 6891.50 | 0.3357 | 0.4682 |
MCF 10A | Omipalisib | 0.01 | uM | 2 | 1250.00 | 585.71 | 1570.33 | 6891.50 | 0.2288 | 0.3072 |
MCF 10A | Omipalisib | 0.031623 | uM | 2 | 1250.00 | 585.71 | 614.33 | 6891.50 | 0.0896 | 0.0052 |
MCF 10A | Omipalisib | 0.1 | uM | 2 | 1250.00 | 585.71 | 140.33 | 6891.50 | 0.0203 | -0.3346 |
MCF 10A | Omipalisib | 0.31623 | uM | 2 | 1250.00 | 585.71 | 112.00 | 6891.50 | 0.0162 | -0.3746 |
MCF 10A | Omipalisib | 1 | uM | 2 | 1250.00 | 585.71 | 44.33 | 6891.50 | 0.0065 | -0.5238 |
MCF 10A | Omipalisib | 3.1623 | uM | 2 | 1250.00 | 585.71 | 48.00 | 6891.50 | 0.0070 | -0.5092 |
MCF 10A | Omipalisib | 10 | uM | 2 | 1250.00 | 585.71 | 199.33 | 6891.50 | 0.0289 | -0.2666 |
MCF 10A | Methotrexate | 0.0016596 | uM | 2 | 1250.00 | 585.71 | 7217.33 | 6891.50 | 1.0469 | 1.0227 |
MCF 10A | Methotrexate | 0.0033113 | uM | 2 | 1250.00 | 585.71 | 7741.00 | 6891.50 | 1.1221 | 1.0637 |
MCF 10A | Methotrexate | 0.01 | uM | 2 | 1250.00 | 585.71 | 7095.33 | 6891.50 | 1.0317 | 1.0148 |
MCF 10A | Methotrexate | 0.031623 | uM | 2 | 1250.00 | 585.71 | 6231.00 | 6891.50 | 0.9064 | 0.9416 |
MCF 10A | Methotrexate | 0.1 | uM | 2 | 1250.00 | 585.71 | 1100.33 | 6891.50 | 0.1595 | 0.1925 |
MCF 10A | Methotrexate | 0.31623 | uM | 2 | 1250.00 | 585.71 | 915.33 | 6891.50 | 0.1329 | 0.1316 |
MCF 10A | Methotrexate | 1 | uM | 2 | 1250.00 | 585.71 | 1002.33 | 6891.50 | 0.1456 | 0.1607 |
MCF 10A | Methotrexate | 3.1623 | uM | 2 | 1250.00 | 585.71 | 1008.33 | 6891.50 | 0.1464 | 0.1647 |
MCF 10A | Methotrexate | 10 | uM | 2 | 1250.00 | 585.71 | 1181.33 | 6891.50 | 0.1718 | 0.2170 |
MCF 10A | Taxol | 0.00016596 | uM | 2 | 1250.00 | 585.71 | 6518.67 | 6891.50 | 0.9455 | 0.9681 |
MCF 10A | Taxol | 0.00033113 | uM | 2 | 1250.00 | 585.71 | 6654.00 | 6891.50 | 0.9675 | 0.9792 |