Breast Cancer Cell Density: Imaging assay of the density- and context-dependence of small molecule perturbagen response in breast cancer cell lines. Dataset 2 of 3: Mean cell count and mean normalized growth rate inhibition values across all replicates. - Dataset (ID:20257)
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| Cell | Small Molecule | Small Mol Concentration | Small Mol Conc Unit | Replicate | Seeding Density | Mean Total Cell Count Before Treatment | Mean Total Cell Count After Treatment | Mean Total Control Cell Count | Mean Relative Cell Count | Mean Normalized Growth Rate Inhibition Value |
|---|---|---|---|---|---|---|---|---|---|---|
| MDA-MB-231 | Linsitinib | 0.1 | uM | 10 | 625.00 | 241.23 | 1317.67 | 1138.92 | 1.1621 | 1.1385 |
| MDA-MB-231 | Linsitinib | 0.31623 | uM | 10 | 625.00 | 241.23 | 1221.67 | 1138.92 | 1.0701 | 1.0581 |
| MDA-MB-231 | Linsitinib | 1 | uM | 10 | 625.00 | 241.23 | 1136.00 | 1138.92 | 0.9952 | 0.9935 |
| MDA-MB-231 | Linsitinib | 3.1623 | uM | 10 | 625.00 | 241.23 | 1037.33 | 1138.92 | 0.9070 | 0.9101 |
| MDA-MB-231 | Linsitinib | 10 | uM | 10 | 625.00 | 241.23 | 877.00 | 1138.92 | 0.7682 | 0.7757 |
| MDA-MB-231 | Linsitinib | 19.9526 | uM | 10 | 625.00 | 241.23 | 515.00 | 1138.92 | 0.4450 | 0.3647 |
| MDA-MB-231 | Palbociclib | 0.0033113 | uM | 10 | 625.00 | 241.23 | 1242.00 | 1226.00 | 1.0977 | 1.2001 |
| MDA-MB-231 | Palbociclib | 0.01 | uM | 10 | 625.00 | 241.23 | 1233.67 | 1226.00 | 1.0454 | 1.0754 |
| MDA-MB-231 | Palbociclib | 0.031623 | uM | 10 | 625.00 | 241.23 | 1206.00 | 1226.00 | 0.9976 | 1.0169 |
| MDA-MB-231 | Palbociclib | 0.1 | uM | 10 | 625.00 | 241.23 | 1037.67 | 1226.00 | 0.8669 | 0.8524 |
| MDA-MB-231 | Palbociclib | 0.31623 | uM | 10 | 625.00 | 241.23 | 824.67 | 1226.00 | 0.6592 | 0.5594 |
| MDA-MB-231 | Palbociclib | 1 | uM | 10 | 625.00 | 241.23 | 568.33 | 1226.00 | 0.4833 | 0.3544 |
| MDA-MB-231 | Palbociclib | 3.1623 | uM | 10 | 625.00 | 241.23 | 477.00 | 1226.00 | 0.4317 | 0.2924 |
| MDA-MB-231 | Palbociclib | 10 | uM | 10 | 625.00 | 241.23 | 401.33 | 1226.00 | 0.3802 | 0.2130 |
| MDA-MB-231 | Palbociclib | 19.9526 | uM | 10 | 625.00 | 241.23 | 412.67 | 1226.00 | 0.3899 | 0.2294 |
| MDA-MB-231 | 17-AAG | 0.0016596 | uM | 10 | 1250.00 | 520.59 | 2841.33 | 2644.17 | 1.0748 | 1.0617 |
| MDA-MB-231 | 17-AAG | 0.0033113 | uM | 10 | 1250.00 | 520.59 | 2904.00 | 2644.17 | 1.0979 | 1.0811 |
| MDA-MB-231 | 17-AAG | 0.01 | uM | 10 | 1250.00 | 520.59 | 3092.33 | 2644.17 | 1.1689 | 1.1363 |
| MDA-MB-231 | 17-AAG | 0.031623 | uM | 10 | 1250.00 | 520.59 | 2912.33 | 2644.17 | 1.1013 | 1.0830 |
| MDA-MB-231 | 17-AAG | 0.1 | uM | 10 | 1250.00 | 520.59 | 2700.33 | 2644.17 | 1.0215 | 1.0173 |
| MDA-MB-231 | 17-AAG | 0.31623 | uM | 10 | 1250.00 | 520.59 | 2849.67 | 2644.17 | 1.0758 | 1.0608 |
| MDA-MB-231 | 17-AAG | 1 | uM | 10 | 1250.00 | 520.59 | 1982.00 | 2644.17 | 0.7496 | 0.7684 |
| MDA-MB-231 | 17-AAG | 3.1623 | uM | 10 | 1250.00 | 520.59 | 801.00 | 2644.17 | 0.3037 | 0.2014 |
| MDA-MB-231 | 17-AAG | 10 | uM | 10 | 1250.00 | 520.59 | 635.00 | 2644.17 | 0.2402 | 0.0882 |
| MDA-MB-231 | Erlotinib | 0.0033113 | uM | 10 | 1250.00 | 520.59 | 2868.67 | 2644.17 | 1.0856 | 1.0700 |