Breast Cancer Cell Density: Imaging assay of the density- and context-dependence of small molecule perturbagen response in breast cancer cell lines. Dataset 2 of 3: Mean cell count and mean normalized growth rate inhibition values across all replicates. - Dataset (ID:20257)
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| Cell | Small Molecule | Small Mol Concentration | Small Mol Conc Unit | Replicate | Seeding Density | Mean Total Cell Count Before Treatment | Mean Total Cell Count After Treatment | Mean Total Control Cell Count | Mean Relative Cell Count | Mean Normalized Growth Rate Inhibition Value |
|---|---|---|---|---|---|---|---|---|---|---|
| Hs 578T | NVP-TAE684 | 10 | uM | 1 | 156.25 | 76.08 | 35.33 | 202.42 | 0.1729 | -0.4292 |
| MCF7 | PLX-4720 | 1 | uM | 1 | 156.25 | 31.46 | 73.00 | 85.83 | 0.8969 | 0.9045 |
| MCF7 | PLX-4720 | 10 | uM | 1 | 156.25 | 31.46 | 101.00 | 85.83 | 1.2769 | 1.4348 |
| MCF7 | PLX-4720 | 3.1623 | uM | 1 | 156.25 | 31.46 | 108.67 | 85.83 | 1.2726 | 1.3866 |
| Hs 578T | Palbociclib | 0.0033113 | uM | 1 | 156.25 | 76.08 | 182.33 | 200.08 | 0.9697 | 1.0944 |
| Hs 578T | Methotrexate | 1 | uM | 1 | 156.25 | 76.08 | 99.33 | 200.08 | 0.4921 | 0.0978 |
| Hs 578T | Etoposide | 0.31623 | uM | 1 | 156.25 | 76.08 | 156.00 | 202.42 | 0.7683 | 0.6529 |
| MCF7 | Methotrexate | 10 | uM | 1 | 156.25 | 31.46 | 73.33 | 70.42 | 1.0565 | 1.1283 |
| Hs 578T | Palbociclib | 0.01 | uM | 1 | 156.25 | 76.08 | 198.00 | 200.08 | 0.9315 | 0.7917 |
| MCF7 | Omipalisib | 0.01 | uM | 1 | 156.25 | 31.46 | 32.33 | 70.42 | 0.4664 | 0.0281 |
| Hs 578T | Omipalisib | 3.1623 | uM | 1 | 156.25 | 76.08 | 43.33 | 200.08 | 0.2282 | -0.3972 |
| MCF7 | Omipalisib | 0.0016596 | uM | 1 | 156.25 | 31.46 | 64.33 | 70.42 | 0.9283 | 0.9010 |
| Hs 578T | Palbociclib | 0.031623 | uM | 1 | 156.25 | 76.08 | 176.67 | 200.08 | 0.8336 | 0.6475 |
| MCF7 | Omipalisib | 1 | uM | 1 | 156.25 | 31.46 | 31.33 | 70.42 | 0.4407 | -0.0229 |
| Hs 578T | Etoposide | 1 | uM | 1 | 156.25 | 76.08 | 75.33 | 202.42 | 0.3736 | -0.0075 |
| MCF7 | Omipalisib | 0.1 | uM | 1 | 156.25 | 31.46 | 31.00 | 70.42 | 0.4502 | 0.0026 |
| Hs 578T | Palbociclib | 0.1 | uM | 1 | 156.25 | 76.08 | 171.00 | 200.08 | 0.8047 | 0.5885 |
| MCF7 | Omipalisib | 3.1623 | uM | 1 | 156.25 | 31.46 | 34.67 | 70.42 | 0.5101 | 0.1173 |
| MCF7 | Methotrexate | 0.0016596 | uM | 1 | 156.25 | 31.46 | 108.67 | 70.42 | 1.5518 | 1.9348 |
| MCF7 | Omipalisib | 10 | uM | 1 | 156.25 | 31.46 | 28.67 | 70.42 | 0.3976 | -0.1123 |
| Hs 578T | Palbociclib | 0.31623 | uM | 1 | 156.25 | 76.08 | 130.67 | 200.08 | 0.5848 | 0.1957 |
| Hs 578T | Methotrexate | 3.1623 | uM | 1 | 156.25 | 76.08 | 119.67 | 200.08 | 0.5482 | 0.1534 |
| Hs 578T | Etoposide | 3.1623 | uM | 1 | 156.25 | 76.08 | 72.33 | 202.42 | 0.3595 | -0.0354 |
| MDA-MB-231 | NVP-TAE684 | 0.1 | uM | 2 | 156.25 | 73.46 | 182.67 | 175.67 | 1.0631 | 1.1248 |
| MDA-MB-231 | NVP-TAE684 | 0.031623 | uM | 2 | 156.25 | 73.46 | 184.33 | 175.67 | 1.0667 | 1.1371 |