Breast Cancer Cell Density: Imaging assay of the density- and context-dependence of small molecule perturbagen response in breast cancer cell lines. Dataset 1 of 3: Cell count and normalized growth rate inhibition values. - Dataset (ID:20256)
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Cell | Small Molecule | Small Mol Concentration | Small Mol Conc Unit | Replicate | Seeding Density | Total Cell Count Before Treatment | Total Cell Count After Treatment | Total Control Cell Count | Relative Cell Count | Normalized Growth Rate Inhibition Value |
---|---|---|---|---|---|---|---|---|---|---|
MCF 10A | Etoposide | 0.31623 | uM | 2 | 1250.00 | 585.71 | 1946.00 | 7278.25 | 0.2674 | 0.3914 |
MCF 10A | PLX-4720 | 0.0033113 | uM | 2 | 1250.00 | 585.71 | 7082.00 | 7278.25 | 0.9730 | 0.9850 |
MCF 10A | NVP-TAE684 | 0.01 | uM | 2 | 1250.00 | 585.71 | 6791.00 | 7278.25 | 0.9331 | 0.9622 |
MCF 10A | Etoposide | 0.0033113 | uM | 2 | 1250.00 | 585.71 | 6540.00 | 7278.25 | 0.8986 | 0.9420 |
MCF 10A | PLX-4720 | 10 | uM | 2 | 1250.00 | 585.71 | 7297.00 | 7278.25 | 1.0026 | 1.0014 |
MCF 10A | Etoposide | 3.1623 | uM | 2 | 1250.00 | 585.71 | 446.00 | 7278.25 | 0.0613 | -0.0722 |
MCF 10A | Nilotinib | 19.9526 | uM | 2 | 1250.00 | 585.71 | 719.00 | 7278.25 | 0.0988 | 0.0580 |
MCF 10A | Nilotinib | 0.1 | uM | 2 | 1250.00 | 585.71 | 8164.00 | 7278.25 | 1.1217 | 1.0642 |
MCF 10A | PLX-4720 | 0.1 | uM | 2 | 1250.00 | 585.71 | 7071.00 | 7278.25 | 0.9715 | 0.9842 |
MCF 10A | PLX-4720 | 1 | uM | 2 | 1250.00 | 585.71 | 7816.00 | 7278.25 | 1.0739 | 1.0396 |
MCF 10A | NVP-TAE684 | 0.1 | uM | 2 | 1250.00 | 585.71 | 5093.00 | 7278.25 | 0.6998 | 0.8129 |
MCF 10A | Nilotinib | 10 | uM | 2 | 1250.00 | 585.71 | 1420.00 | 7278.25 | 0.1951 | 0.2758 |
MCF 10A | Nilotinib | 0.01 | uM | 2 | 1250.00 | 585.71 | 6876.00 | 7278.25 | 0.9447 | 0.9690 |
MCF 10A | Etoposide | 19.9526 | uM | 2 | 1250.00 | 585.71 | 297.00 | 7278.25 | 0.0408 | -0.1704 |
MCF 10A | 0 | uM | 2 | 1250.00 | 585.71 | 7436.00 | 7278.25 | 1.0217 | 1.0118 | |
MCF 10A | 0 | uM | 2 | 1250.00 | 585.71 | 6076.00 | 7278.25 | 0.8348 | 0.9031 | |
MCF 10A | 0 | uM | 2 | 1250.00 | 585.71 | 6423.00 | 7278.25 | 0.8825 | 0.9324 | |
MCF 10A | 0 | uM | 2 | 1250.00 | 585.71 | 6738.00 | 7278.25 | 0.9258 | 0.9580 | |
MCF 10A | Etoposide | 1 | uM | 2 | 1250.00 | 585.71 | 515.00 | 7278.25 | 0.0708 | -0.0348 |
MCF 10A | NVP-TAE684 | 0.0016596 | uM | 2 | 1250.00 | 585.71 | 6611.00 | 7278.25 | 0.9083 | 0.9478 |
MCF 10A | 0 | uM | 2 | 1250.00 | 585.71 | 6341.00 | 7278.25 | 0.8712 | 0.9256 | |
MCF 10A | NVP-TAE684 | 10 | uM | 2 | 1250.00 | 585.71 | 338.00 | 7278.25 | 0.0464 | -0.1404 |
MCF 10A | Nilotinib | 0.0033113 | uM | 2 | 1250.00 | 585.71 | 8405.00 | 7278.25 | 1.1548 | 1.0808 |
MCF 10A | NVP-TAE684 | 0.0033113 | uM | 2 | 1250.00 | 585.71 | 8028.00 | 7278.25 | 1.1030 | 1.0547 |
MCF 10A | Nilotinib | 0.31623 | uM | 2 | 1250.00 | 585.71 | 8206.00 | 7278.25 | 1.1275 | 1.0671 |