Breast Cancer Cell Density: Imaging assay of the density- and context-dependence of small molecule perturbagen response in breast cancer cell lines. Dataset 1 of 3: Cell count and normalized growth rate inhibition values. - Dataset (ID:20256)
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Cell | Small Molecule | Small Mol Concentration | Small Mol Conc Unit | Replicate | Seeding Density | Total Cell Count Before Treatment | Total Cell Count After Treatment | Total Control Cell Count | Relative Cell Count | Normalized Growth Rate Inhibition Value |
---|---|---|---|---|---|---|---|---|---|---|
MCF 10A | 17-AAG | 0.1 | uM | 9 | 1250.00 | 369.45 | 309.00 | 6773.25 | 0.0456 | -0.0417 |
MCF 10A | Linsitinib | 0.0033113 | uM | 9 | 1250.00 | 369.45 | 7805.00 | 6773.25 | 1.1523 | 1.0687 |
MCF 10A | Linsitinib | 3.1623 | uM | 9 | 1250.00 | 369.45 | 1890.00 | 6773.25 | 0.2790 | 0.4755 |
MCF 10A | Erlotinib | 0.0033113 | uM | 9 | 1250.00 | 369.45 | 4824.00 | 6773.25 | 0.7122 | 0.8446 |
MCF 10A | Lapatinib | 1 | uM | 9 | 1250.00 | 369.45 | 4130.00 | 6773.25 | 0.6098 | 0.7776 |
MCF 10A | 0 | uM | 9 | 1250.00 | 369.45 | 7156.00 | 6773.25 | 1.0565 | 1.0264 | |
MCF 10A | 0 | uM | 9 | 2500.00 | 860.55 | 10133.00 | 10215.25 | 0.9920 | 0.9955 | |
MCF 10A | Linsitinib | 0.1 | uM | 9 | 2500.00 | 860.55 | 9480.00 | 10215.25 | 0.9280 | 0.9586 |
MCF 10A | Lapatinib | 3.1623 | uM | 9 | 2500.00 | 860.55 | 4964.00 | 10215.25 | 0.4859 | 0.6339 |
MCF 10A | Linsitinib | 10 | uM | 9 | 2500.00 | 860.55 | 5027.00 | 10215.25 | 0.4921 | 0.6397 |
MCF 10A | Erlotinib | 0.1 | uM | 9 | 2500.00 | 860.55 | 9665.00 | 10215.25 | 0.9461 | 0.9692 |
MCF 10A | Erlotinib | 19.9526 | uM | 9 | 2500.00 | 860.55 | 1114.00 | 10215.25 | 0.1091 | 0.0750 |
MCF 10A | Erlotinib | 1 | uM | 9 | 2500.00 | 860.55 | 1405.00 | 10215.25 | 0.1375 | 0.1472 |
MCF 10A | 17-AAG | 0.0031623 | uM | 9 | 2500.00 | 860.55 | 10135.00 | 10215.25 | 0.9921 | 0.9956 |
MCF 10A | 0 | uM | 9 | 2500.00 | 860.55 | 10032.00 | 10215.25 | 0.9821 | 0.9899 | |
MCF 10A | Linsitinib | 1 | uM | 9 | 2500.00 | 860.55 | 7410.00 | 10215.25 | 0.7254 | 0.8280 |
MCF 10A | Erlotinib | 0.031623 | uM | 9 | 2500.00 | 860.55 | 10399.00 | 10215.25 | 1.0180 | 1.0100 |
MCF 10A | Lapatinib | 0.31623 | uM | 9 | 2500.00 | 860.55 | 9952.00 | 10215.25 | 0.9742 | 0.9854 |
MCF 10A | 17-AAG | 0.0001 | uM | 9 | 2500.00 | 860.55 | 10000.00 | 10215.25 | 0.9789 | 0.9881 |
MCF 10A | 0 | uM | 9 | 2500.00 | 860.55 | 10391.00 | 10215.25 | 1.0172 | 1.0096 | |
MCF 10A | 17-AAG | 0.000302 | uM | 9 | 2500.00 | 860.55 | 10560.00 | 10215.25 | 1.0337 | 1.0187 |
MCF 10A | Erlotinib | 10 | uM | 9 | 2500.00 | 860.55 | 1115.00 | 10215.25 | 0.1092 | 0.0753 |
MCF 10A | 17-AAG | 0.001 | uM | 9 | 2500.00 | 860.55 | 10281.00 | 10215.25 | 1.0064 | 1.0036 |
MCF 10A | Lapatinib | 10 | uM | 9 | 2500.00 | 860.55 | 1173.00 | 10215.25 | 0.1148 | 0.0907 |
MCF 10A | 0 | uM | 9 | 2500.00 | 860.55 | 10225.00 | 10215.25 | 1.0010 | 1.0005 |