Breast Cancer Cell Density: Imaging assay of the density- and context-dependence of small molecule perturbagen response in breast cancer cell lines. Dataset 1 of 3: Cell count and normalized growth rate inhibition values. - Dataset (ID:20256)
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Cell | Small Molecule | Small Mol Concentration | Small Mol Conc Unit | Replicate | Seeding Density | Total Cell Count Before Treatment | Total Cell Count After Treatment | Total Control Cell Count | Relative Cell Count | Normalized Growth Rate Inhibition Value |
---|---|---|---|---|---|---|---|---|---|---|
MCF 10A | Lapatinib | 0.1 | uM | 9 | 5000.00 | 2099.14 | 11858.00 | 11890.75 | 0.9973 | 0.9978 |
MCF 10A | 0 | uM | 9 | 5000.00 | 2099.14 | 11927.00 | 11890.75 | 1.0030 | 1.0024 | |
MCF 10A | 17-AAG | 0.000066069 | uM | 9 | 5000.00 | 2099.14 | 12157.00 | 11890.75 | 1.0224 | 1.0178 |
MCF 10A | 0 | uM | 9 | 5000.00 | 2099.14 | 12150.00 | 11890.75 | 1.0218 | 1.0173 | |
MCF 10A | Linsitinib | 0.01 | uM | 9 | 5000.00 | 2099.14 | 12249.00 | 11890.75 | 1.0301 | 1.0239 |
MCF 10A | 17-AAG | 0.1 | uM | 9 | 5000.00 | 2099.14 | 1706.00 | 11890.75 | 0.1435 | -0.0795 |
MCF 10A | Lapatinib | 0.01 | uM | 9 | 5000.00 | 2099.14 | 12070.00 | 11890.75 | 1.0151 | 1.0120 |
MCF 10A | Lapatinib | 0.31623 | uM | 9 | 5000.00 | 2099.14 | 11833.00 | 11890.75 | 0.9951 | 0.9961 |
MCF 10A | 17-AAG | 0.31623 | uM | 9 | 5000.00 | 2099.14 | 1550.00 | 11890.75 | 0.1304 | -0.1142 |
MCF 10A | Erlotinib | 0.1 | uM | 9 | 5000.00 | 2099.14 | 11726.00 | 11890.75 | 0.9861 | 0.9889 |
MCF 10A | 0 | uM | 9 | 5000.00 | 2099.14 | 12193.00 | 11890.75 | 1.0254 | 1.0202 | |
MCF 10A | Erlotinib | 19.9526 | uM | 9 | 5000.00 | 2099.14 | 2580.00 | 11890.75 | 0.2170 | 0.0859 |
MCF 10A | Lapatinib | 0.031623 | uM | 9 | 5000.00 | 2099.14 | 11819.00 | 11890.75 | 0.9940 | 0.9952 |
MCF 10A | Lapatinib | 0.0016596 | uM | 9 | 5000.00 | 2099.14 | 11594.00 | 11890.75 | 0.9750 | 0.9799 |
MCF 10A | 17-AAG | 0.031623 | uM | 9 | 5000.00 | 2099.14 | 5523.00 | 11890.75 | 0.4645 | 0.4721 |
MCF 10A | 0 | uM | 9 | 5000.00 | 2099.14 | 11766.00 | 11890.75 | 0.9895 | 0.9916 | |
MCF 10A | 0 | uM | 9 | 156.25 | 46.09 | 243.00 | 283.50 | 0.8571 | 0.8858 | |
MCF 10A | 0 | uM | 9 | 156.25 | 46.09 | 273.00 | 283.50 | 0.9630 | 0.9714 | |
MCF 10A | Erlotinib | 0.0033113 | uM | 9 | 156.25 | 46.09 | 182.00 | 283.50 | 0.6420 | 0.6888 |
MCF 10A | 17-AAG | 0.001 | uM | 9 | 156.25 | 46.09 | 359.00 | 283.50 | 1.2663 | 1.1885 |
MCF 10A | 17-AAG | 0.000066069 | uM | 9 | 156.25 | 46.09 | 380.00 | 283.50 | 1.3404 | 1.2365 |
MCF 10A | Linsitinib | 3.1623 | uM | 9 | 156.25 | 46.09 | 86.00 | 283.50 | 0.3034 | 0.2687 |
MCF 10A | Erlotinib | 19.9526 | uM | 9 | 156.25 | 46.09 | 53.00 | 283.50 | 0.1870 | 0.0547 |
MCF 10A | Lapatinib | 0.1 | uM | 9 | 156.25 | 46.09 | 375.00 | 283.50 | 1.3228 | 1.2253 |
MCF 10A | Lapatinib | 0.0016596 | uM | 9 | 156.25 | 46.09 | 542.00 | 283.50 | 1.9118 | 1.5611 |