Breast Cancer Cell Density: Imaging assay of the density- and context-dependence of small molecule perturbagen response in breast cancer cell lines. Dataset 1 of 3: Cell count and normalized growth rate inhibition values. - Dataset (ID:20256)
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Cell | Small Molecule | Small Mol Concentration | Small Mol Conc Unit | Replicate | Seeding Density | Total Cell Count Before Treatment | Total Cell Count After Treatment | Total Control Cell Count | Relative Cell Count | Normalized Growth Rate Inhibition Value |
---|---|---|---|---|---|---|---|---|---|---|
MCF 10A | Lapatinib | 0.031623 | uM | 9 | 2500.00 | 860.55 | 10950.00 | 10674.25 | 1.0258 | 1.0141 |
MCF 10A | Lapatinib | 0.0033113 | uM | 9 | 2500.00 | 860.55 | 10887.00 | 10674.25 | 1.0199 | 1.0109 |
MCF 10A | 17-AAG | 0.1 | uM | 9 | 2500.00 | 860.55 | 623.00 | 10674.25 | 0.0584 | -0.0851 |
MCF 10A | Linsitinib | 0.0033113 | uM | 9 | 2500.00 | 860.55 | 11132.00 | 10674.25 | 1.0429 | 1.0233 |
MCF 10A | Linsitinib | 3.1623 | uM | 9 | 2500.00 | 860.55 | 5673.00 | 10674.25 | 0.5315 | 0.6806 |
MCF 10A | Erlotinib | 0.0033113 | uM | 9 | 2500.00 | 860.55 | 10942.00 | 10674.25 | 1.0251 | 1.0137 |
MCF 10A | Lapatinib | 1 | uM | 9 | 2500.00 | 860.55 | 10476.00 | 10674.25 | 0.9814 | 0.9897 |
MCF 10A | 0 | uM | 9 | 2500.00 | 860.55 | 10913.00 | 10674.25 | 1.0224 | 1.0122 | |
MCF 10A | 0 | uM | 9 | 5000.00 | 2099.14 | 11710.00 | 11908.75 | 0.9833 | 0.9866 | |
MCF 10A | Linsitinib | 0.1 | uM | 9 | 5000.00 | 2099.14 | 11732.00 | 11908.75 | 0.9852 | 0.9881 |
MCF 10A | Lapatinib | 3.1623 | uM | 9 | 5000.00 | 2099.14 | 8723.00 | 11908.75 | 0.7325 | 0.7662 |
MCF 10A | Linsitinib | 10 | uM | 9 | 5000.00 | 2099.14 | 7774.00 | 11908.75 | 0.6528 | 0.6868 |
MCF 10A | Erlotinib | 0.1 | uM | 9 | 5000.00 | 2099.14 | 11827.00 | 11908.75 | 0.9931 | 0.9945 |
MCF 10A | Erlotinib | 19.9526 | uM | 9 | 5000.00 | 2099.14 | 2270.00 | 11908.75 | 0.1906 | 0.0317 |
MCF 10A | Erlotinib | 1 | uM | 9 | 5000.00 | 2099.14 | 2766.00 | 11908.75 | 0.2323 | 0.1165 |
MCF 10A | 17-AAG | 0.0031623 | uM | 9 | 5000.00 | 2099.14 | 11835.00 | 11908.75 | 0.9938 | 0.9950 |
MCF 10A | 0 | uM | 9 | 5000.00 | 2099.14 | 11851.00 | 11908.75 | 0.9952 | 0.9961 | |
MCF 10A | Linsitinib | 1 | uM | 9 | 5000.00 | 2099.14 | 9952.00 | 11908.75 | 0.8357 | 0.8617 |
MCF 10A | Erlotinib | 0.031623 | uM | 9 | 5000.00 | 2099.14 | 12202.00 | 11908.75 | 1.0246 | 1.0195 |
MCF 10A | Lapatinib | 0.31623 | uM | 9 | 5000.00 | 2099.14 | 7944.00 | 11908.75 | 0.6671 | 0.7014 |
MCF 10A | 17-AAG | 0.0001 | uM | 9 | 5000.00 | 2099.14 | 11967.00 | 11908.75 | 1.0049 | 1.0039 |
MCF 10A | 0 | uM | 9 | 5000.00 | 2099.14 | 11978.00 | 11908.75 | 1.0058 | 1.0046 | |
MCF 10A | 17-AAG | 0.000302 | uM | 9 | 5000.00 | 2099.14 | 11721.00 | 11908.75 | 0.9842 | 0.9874 |
MCF 10A | Erlotinib | 10 | uM | 9 | 5000.00 | 2099.14 | 2570.00 | 11908.75 | 0.2158 | 0.0842 |
MCF 10A | 17-AAG | 0.001 | uM | 9 | 5000.00 | 2099.14 | 11861.00 | 11908.75 | 0.9960 | 0.9968 |