Breast Cancer Cell Density: Imaging assay of the density- and context-dependence of small molecule perturbagen response in breast cancer cell lines. Dataset 1 of 3: Cell count and normalized growth rate inhibition values. - Dataset (ID:20256)
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Cell | Small Molecule | Small Mol Concentration | Small Mol Conc Unit | Replicate | Seeding Density | Total Cell Count Before Treatment | Total Cell Count After Treatment | Total Control Cell Count | Relative Cell Count | Normalized Growth Rate Inhibition Value |
---|---|---|---|---|---|---|---|---|---|---|
MCF 10A | 17-AAG | 0.031623 | uM | 9 | 1250.00 | 369.45 | 407.00 | 6493.50 | 0.0627 | 0.0237 |
MCF 10A | Lapatinib | 0.1 | uM | 9 | 1250.00 | 369.45 | 7562.00 | 6493.50 | 1.1645 | 1.0750 |
MCF 10A | Erlotinib | 0.31623 | uM | 9 | 1250.00 | 369.45 | 3367.00 | 6493.50 | 0.5185 | 0.7063 |
MCF 10A | Linsitinib | 0.31623 | uM | 9 | 1250.00 | 369.45 | 7109.00 | 6493.50 | 1.0948 | 1.0443 |
MCF 10A | Lapatinib | 0.0016596 | uM | 9 | 1250.00 | 369.45 | 6654.00 | 6493.50 | 1.0247 | 1.0118 |
MCF 10A | 17-AAG | 0.01 | uM | 9 | 1250.00 | 369.45 | 5083.00 | 6493.50 | 0.7828 | 0.8850 |
MCF 10A | Lapatinib | 0.031623 | uM | 9 | 1250.00 | 369.45 | 7328.00 | 6493.50 | 1.1285 | 1.0593 |
MCF 10A | Lapatinib | 0.0033113 | uM | 9 | 1250.00 | 369.45 | 8230.00 | 6493.50 | 1.2674 | 1.1180 |
MCF 10A | 17-AAG | 0.1 | uM | 9 | 1250.00 | 369.45 | 239.00 | 6493.50 | 0.0368 | -0.1000 |
MCF 10A | Linsitinib | 0.0033113 | uM | 9 | 1250.00 | 369.45 | 7058.00 | 6493.50 | 1.0869 | 1.0407 |
MCF 10A | Linsitinib | 3.1623 | uM | 9 | 1250.00 | 369.45 | 2410.00 | 6493.50 | 0.3711 | 0.5738 |
MCF 10A | Erlotinib | 0.0033113 | uM | 9 | 1250.00 | 369.45 | 8350.00 | 6493.50 | 1.2859 | 1.1254 |
MCF 10A | Lapatinib | 1 | uM | 9 | 1250.00 | 369.45 | 4745.00 | 6493.50 | 0.7307 | 0.8539 |
MCF 10A | 0 | uM | 9 | 1250.00 | 369.45 | 5939.00 | 6493.50 | 0.9146 | 0.9573 | |
MCF 10A | 0 | uM | 9 | 2500.00 | 860.55 | 10607.00 | 10674.25 | 0.9937 | 0.9965 | |
MCF 10A | Linsitinib | 0.1 | uM | 9 | 2500.00 | 860.55 | 10680.00 | 10674.25 | 1.0005 | 1.0003 |
MCF 10A | Lapatinib | 3.1623 | uM | 9 | 2500.00 | 860.55 | 5470.00 | 10674.25 | 0.5125 | 0.6638 |
MCF 10A | Linsitinib | 10 | uM | 9 | 2500.00 | 860.55 | 5095.00 | 10674.25 | 0.4773 | 0.6316 |
MCF 10A | Erlotinib | 0.1 | uM | 9 | 2500.00 | 860.55 | 10669.00 | 10674.25 | 0.9995 | 0.9997 |
MCF 10A | Erlotinib | 19.9526 | uM | 9 | 2500.00 | 860.55 | 1014.00 | 10674.25 | 0.0950 | 0.0462 |
MCF 10A | Erlotinib | 1 | uM | 9 | 2500.00 | 860.55 | 1139.00 | 10674.25 | 0.1067 | 0.0802 |
MCF 10A | 17-AAG | 0.0031623 | uM | 9 | 2500.00 | 860.55 | 10844.00 | 10674.25 | 1.0159 | 1.0087 |
MCF 10A | 0 | uM | 9 | 2500.00 | 860.55 | 10620.00 | 10674.25 | 0.9949 | 0.9972 | |
MCF 10A | Linsitinib | 1 | uM | 9 | 2500.00 | 860.55 | 7677.00 | 10674.25 | 0.7192 | 0.8265 |
MCF 10A | Erlotinib | 0.031623 | uM | 9 | 2500.00 | 860.55 | 11757.00 | 10674.25 | 1.1014 | 1.0539 |