Breast Cancer Cell Density: Imaging assay of the density- and context-dependence of small molecule perturbagen response in breast cancer cell lines. Dataset 1 of 3: Cell count and normalized growth rate inhibition values. - Dataset (ID:20256)
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Cell | Small Molecule | Small Mol Concentration | Small Mol Conc Unit | Replicate | Seeding Density | Total Cell Count Before Treatment | Total Cell Count After Treatment | Total Control Cell Count | Relative Cell Count | Normalized Growth Rate Inhibition Value |
---|---|---|---|---|---|---|---|---|---|---|
MCF 10A | Lapatinib | 0.0033113 | uM | 9 | 156.25 | 46.09 | 441.00 | 289.00 | 1.5260 | 1.3460 |
MCF 10A | 17-AAG | 0.1 | uM | 9 | 156.25 | 46.09 | 27.00 | 289.00 | 0.0934 | -0.1828 |
MCF 10A | Linsitinib | 0.0033113 | uM | 9 | 156.25 | 46.09 | 280.00 | 289.00 | 0.9689 | 0.9763 |
MCF 10A | Linsitinib | 3.1623 | uM | 9 | 156.25 | 46.09 | 99.00 | 289.00 | 0.3426 | 0.3346 |
MCF 10A | Erlotinib | 0.0033113 | uM | 9 | 156.25 | 46.09 | 424.00 | 289.00 | 1.4671 | 1.3114 |
MCF 10A | Lapatinib | 1 | uM | 9 | 156.25 | 46.09 | 220.00 | 289.00 | 0.7613 | 0.8043 |
MCF 10A | 0 | uM | 9 | 156.25 | 46.09 | 207.00 | 289.00 | 0.7163 | 0.7632 | |
MCF 10A | 0 | uM | 9 | 312.50 | 96.23 | 714.00 | 987.00 | 0.7234 | 0.8162 | |
MCF 10A | Linsitinib | 0.1 | uM | 9 | 312.50 | 96.23 | 958.00 | 987.00 | 0.9706 | 0.9823 |
MCF 10A | Lapatinib | 3.1623 | uM | 9 | 312.50 | 96.23 | 838.00 | 987.00 | 0.8490 | 0.9049 |
MCF 10A | Linsitinib | 10 | uM | 9 | 312.50 | 96.23 | 123.00 | 987.00 | 0.1246 | 0.0758 |
MCF 10A | Erlotinib | 0.1 | uM | 9 | 312.50 | 96.23 | 1019.00 | 987.00 | 1.0324 | 1.0191 |
MCF 10A | Erlotinib | 19.9526 | uM | 9 | 312.50 | 96.23 | 120.00 | 987.00 | 0.1216 | 0.0679 |
MCF 10A | Erlotinib | 1 | uM | 9 | 312.50 | 96.23 | 132.00 | 987.00 | 0.1337 | 0.0987 |
MCF 10A | 17-AAG | 0.0031623 | uM | 9 | 312.50 | 96.23 | 1069.00 | 987.00 | 1.0831 | 1.0481 |
MCF 10A | 0 | uM | 9 | 312.50 | 96.23 | 1309.00 | 987.00 | 1.3262 | 1.1754 | |
MCF 10A | Linsitinib | 1 | uM | 9 | 312.50 | 96.23 | 475.00 | 987.00 | 0.4813 | 0.6086 |
MCF 10A | Erlotinib | 0.031623 | uM | 9 | 312.50 | 96.23 | 1626.00 | 987.00 | 1.6474 | 1.3205 |
MCF 10A | Lapatinib | 0.31623 | uM | 9 | 312.50 | 96.23 | 1485.00 | 987.00 | 1.5046 | 1.2587 |
MCF 10A | 17-AAG | 0.0001 | uM | 9 | 312.50 | 96.23 | 1737.00 | 987.00 | 1.7599 | 1.3666 |
MCF 10A | 0 | uM | 9 | 312.50 | 96.23 | 1539.00 | 987.00 | 1.5593 | 1.2828 | |
MCF 10A | 17-AAG | 0.000302 | uM | 9 | 312.50 | 96.23 | 1361.00 | 987.00 | 1.3789 | 1.2008 |
MCF 10A | Erlotinib | 10 | uM | 9 | 312.50 | 96.23 | 125.00 | 987.00 | 0.1267 | 0.0810 |
MCF 10A | 17-AAG | 0.001 | uM | 9 | 312.50 | 96.23 | 1367.00 | 987.00 | 1.3850 | 1.2037 |
MCF 10A | Lapatinib | 10 | uM | 9 | 312.50 | 96.23 | 47.00 | 987.00 | 0.0476 | -0.1921 |