Breast Cancer Cell Density: Imaging assay of the density- and context-dependence of small molecule perturbagen response in breast cancer cell lines. Dataset 1 of 3: Cell count and normalized growth rate inhibition values. - Dataset (ID:20256)
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Cell | Small Molecule | Small Mol Concentration | Small Mol Conc Unit | Replicate | Seeding Density | Total Cell Count Before Treatment | Total Cell Count After Treatment | Total Control Cell Count | Relative Cell Count | Normalized Growth Rate Inhibition Value |
---|---|---|---|---|---|---|---|---|---|---|
MCF 10A | Erlotinib | 0.01 | uM | 9 | 5000.00 | 2099.14 | 12090.00 | 11494.75 | 1.0518 | 1.0416 |
MCF 10A | Linsitinib | 0.01 | uM | 9 | 5000.00 | 2099.14 | 12126.00 | 11494.75 | 1.0549 | 1.0441 |
MCF 10A | 17-AAG | 0.0001 | uM | 9 | 5000.00 | 2099.14 | 12039.00 | 11494.75 | 1.0473 | 1.0381 |
MCF 10A | 17-AAG | 0.01 | uM | 9 | 5000.00 | 2099.14 | 12043.00 | 11494.75 | 1.0477 | 1.0384 |
MCF 10A | Linsitinib | 10 | uM | 9 | 5000.00 | 2099.14 | 7922.00 | 11494.75 | 0.6892 | 0.7184 |
MCF 10A | 0 | uM | 9 | 5000.00 | 2099.14 | 11999.00 | 11494.75 | 1.0439 | 1.0353 | |
MCF 10A | Lapatinib | 1 | uM | 9 | 5000.00 | 2099.14 | 11303.00 | 11494.75 | 0.9833 | 0.9863 |
MCF 10A | Lapatinib | 10 | uM | 9 | 5000.00 | 2099.14 | 1817.00 | 11494.75 | 0.1581 | -0.0571 |
MCF 10A | Lapatinib | 0.0033113 | uM | 9 | 5000.00 | 2099.14 | 11942.00 | 11494.75 | 1.0389 | 1.0314 |
MCF 10A | Linsitinib | 0.1 | uM | 9 | 5000.00 | 2099.14 | 11991.00 | 11494.75 | 1.0432 | 1.0348 |
MCF 10A | Lapatinib | 0.031623 | uM | 9 | 5000.00 | 2099.14 | 12141.00 | 11494.75 | 1.0562 | 1.0451 |
MCF 10A | 17-AAG | 0.031623 | uM | 9 | 5000.00 | 2099.14 | 6636.00 | 11494.75 | 0.5773 | 0.5987 |
MCF 10A | 0 | uM | 9 | 5000.00 | 2099.14 | 11606.00 | 11494.75 | 1.0097 | 1.0079 | |
MCF 10A | 0 | uM | 9 | 156.25 | 46.09 | 295.00 | 289.00 | 1.0208 | 1.0156 | |
MCF 10A | Linsitinib | 0.1 | uM | 9 | 156.25 | 46.09 | 203.00 | 289.00 | 0.7024 | 0.7503 |
MCF 10A | Lapatinib | 3.1623 | uM | 9 | 156.25 | 46.09 | 197.00 | 289.00 | 0.6817 | 0.7306 |
MCF 10A | Linsitinib | 10 | uM | 9 | 156.25 | 46.09 | 63.00 | 289.00 | 0.2180 | 0.1252 |
MCF 10A | Erlotinib | 0.1 | uM | 9 | 156.25 | 46.09 | 283.00 | 289.00 | 0.9792 | 0.9842 |
MCF 10A | Erlotinib | 19.9526 | uM | 9 | 156.25 | 46.09 | 83.00 | 289.00 | 0.2872 | 0.2487 |
MCF 10A | Erlotinib | 1 | uM | 9 | 156.25 | 46.09 | 65.00 | 289.00 | 0.2249 | 0.1386 |
MCF 10A | 17-AAG | 0.0031623 | uM | 9 | 156.25 | 46.09 | 114.00 | 289.00 | 0.3945 | 0.4077 |
MCF 10A | 0 | uM | 9 | 156.25 | 46.09 | 484.00 | 289.00 | 1.6747 | 1.4299 | |
MCF 10A | Linsitinib | 1 | uM | 9 | 156.25 | 46.09 | 177.00 | 289.00 | 0.6125 | 0.6620 |
MCF 10A | Erlotinib | 0.031623 | uM | 9 | 156.25 | 46.09 | 584.00 | 289.00 | 2.0208 | 1.6085 |
MCF 10A | Lapatinib | 0.31623 | uM | 9 | 156.25 | 46.09 | 775.00 | 289.00 | 2.6817 | 1.9026 |