Breast Cancer Cell Density: Imaging assay of the density- and context-dependence of small molecule perturbagen response in breast cancer cell lines. Dataset 1 of 3: Cell count and normalized growth rate inhibition values. - Dataset (ID:20256)
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Cell | Small Molecule | Small Mol Concentration | Small Mol Conc Unit | Replicate | Seeding Density | Total Cell Count Before Treatment | Total Cell Count After Treatment | Total Control Cell Count | Relative Cell Count | Normalized Growth Rate Inhibition Value |
---|---|---|---|---|---|---|---|---|---|---|
MCF 10A | Erlotinib | 1 | uM | 8 | 312.50 | 114.17 | 155.00 | 1546.50 | 0.1002 | 0.0847 |
MCF 10A | 17-AAG | 0.000302 | uM | 8 | 312.50 | 114.17 | 1119.00 | 1546.50 | 0.7236 | 0.8351 |
MCF 10A | Lapatinib | 3.1623 | uM | 8 | 312.50 | 114.17 | 403.00 | 1546.50 | 0.2606 | 0.3986 |
MCF 10A | 17-AAG | 0.31623 | uM | 8 | 312.50 | 114.17 | 80.00 | 1546.50 | 0.0517 | -0.0903 |
MCF 10A | 0 | uM | 8 | 312.50 | 114.17 | 941.00 | 1546.50 | 0.6085 | 0.7524 | |
MCF 10A | 0 | uM | 8 | 312.50 | 114.17 | 641.00 | 1546.50 | 0.4145 | 0.5823 | |
MCF 10A | 0 | uM | 8 | 312.50 | 114.17 | 1413.00 | 1546.50 | 0.9137 | 0.9526 | |
MCF 10A | 0 | uM | 8 | 312.50 | 114.17 | 1364.00 | 1546.50 | 0.8820 | 0.9343 | |
MCF 10A | Linsitinib | 1 | uM | 8 | 312.50 | 114.17 | 370.00 | 1546.50 | 0.2393 | 0.3672 |
MCF 10A | Erlotinib | 0.31623 | uM | 8 | 312.50 | 114.17 | 1114.00 | 1546.50 | 0.7203 | 0.8329 |
MCF 10A | 0 | uM | 8 | 312.50 | 114.17 | 2114.00 | 1546.50 | 1.3670 | 1.1734 | |
MCF 10A | Linsitinib | 19.9526 | uM | 8 | 312.50 | 114.17 | 182.00 | 1546.50 | 0.1177 | 0.1321 |
MCF 10A | Linsitinib | 0.0033113 | uM | 8 | 312.50 | 114.17 | 1615.00 | 1546.50 | 1.0443 | 1.0232 |
MCF 10A | Erlotinib | 10 | uM | 8 | 312.50 | 114.17 | 175.00 | 1546.50 | 0.1132 | 0.1203 |
MCF 10A | Erlotinib | 3.1623 | uM | 8 | 312.50 | 114.17 | 200.00 | 1546.50 | 0.1293 | 0.1608 |
MCF 10A | 17-AAG | 0.0031623 | uM | 8 | 312.50 | 114.17 | 1166.00 | 1546.50 | 0.7540 | 0.8553 |
MCF 10A | Erlotinib | 0.01 | uM | 8 | 312.50 | 114.17 | 2136.00 | 1546.50 | 1.3812 | 1.1794 |
MCF 10A | Linsitinib | 0.01 | uM | 8 | 312.50 | 114.17 | 1763.00 | 1546.50 | 1.1400 | 1.0709 |
MCF 10A | 17-AAG | 0.0001 | uM | 8 | 312.50 | 114.17 | 2689.00 | 1546.50 | 1.7388 | 1.3170 |
MCF 10A | 17-AAG | 0.01 | uM | 8 | 312.50 | 114.17 | 209.00 | 1546.50 | 0.1351 | 0.1745 |
MCF 10A | Linsitinib | 10 | uM | 8 | 312.50 | 114.17 | 240.00 | 1546.50 | 0.1552 | 0.2185 |
MCF 10A | 0 | uM | 8 | 312.50 | 114.17 | 1836.00 | 1546.50 | 1.1872 | 1.0934 | |
MCF 10A | Lapatinib | 1 | uM | 8 | 312.50 | 114.17 | 1540.00 | 1546.50 | 0.9958 | 0.9978 |
MCF 10A | Lapatinib | 10 | uM | 8 | 312.50 | 114.17 | 79.00 | 1546.50 | 0.0511 | -0.0933 |
MCF 10A | Lapatinib | 0.0033113 | uM | 8 | 312.50 | 114.17 | 1407.00 | 1546.50 | 0.9098 | 0.9503 |