Breast Cancer Cell Density: Imaging assay of the density- and context-dependence of small molecule perturbagen response in breast cancer cell lines. Dataset 1 of 3: Cell count and normalized growth rate inhibition values. - Dataset (ID:20256)
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Cell | Small Molecule | Small Mol Concentration | Small Mol Conc Unit | Replicate | Seeding Density | Total Cell Count Before Treatment | Total Cell Count After Treatment | Total Control Cell Count | Relative Cell Count | Normalized Growth Rate Inhibition Value |
---|---|---|---|---|---|---|---|---|---|---|
MCF 10A | 17-AAG | 0.1 | uM | 7 | 1250.00 | 252.38 | 363.00 | 11119.50 | 0.0326 | 0.0688 |
MCF 10A | Lapatinib | 0.01 | uM | 7 | 1250.00 | 252.38 | 10358.00 | 11119.50 | 0.9315 | 0.9742 |
MCF 10A | 0 | uM | 7 | 1250.00 | 252.38 | 9898.00 | 11119.50 | 0.8902 | 0.9578 | |
MCF 10A | 0 | uM | 7 | 1250.00 | 252.38 | 1.00 | 11119.50 | 0.0001 | -0.6368 | |
MCF 10A | 0 | uM | 7 | 2500.00 | 469.42 | 0.00 | 11060.25 | 0.0000 | -1.0000 | |
MCF 10A | 0 | uM | 7 | 2500.00 | 469.42 | 11257.00 | 11060.25 | 1.0178 | 1.0078 | |
MCF 10A | 0 | uM | 7 | 2500.00 | 469.42 | 11494.00 | 11060.25 | 1.0392 | 1.0169 | |
MCF 10A | 17-AAG | 3.1623 | uM | 7 | 2500.00 | 469.42 | 971.00 | 11060.25 | 0.0878 | 0.1729 |
MCF 10A | Lapatinib | 0.0033113 | uM | 7 | 2500.00 | 469.42 | 11744.00 | 11060.25 | 1.0618 | 1.0265 |
MCF 10A | Lapatinib | 0.031623 | uM | 7 | 2500.00 | 469.42 | 11223.00 | 11060.25 | 1.0147 | 1.0064 |
MCF 10A | 17-AAG | 0.0033113 | uM | 7 | 2500.00 | 469.42 | 11087.00 | 11060.25 | 1.0024 | 1.0011 |
MCF 10A | Linsitinib | 1 | uM | 7 | 2500.00 | 469.42 | 7154.00 | 11060.25 | 0.6468 | 0.8177 |
MCF 10A | Lapatinib | 0.0016596 | uM | 7 | 2500.00 | 469.42 | 11471.00 | 11060.25 | 1.0371 | 1.0161 |
MCF 10A | 0 | uM | 7 | 2500.00 | 469.42 | 11493.00 | 11060.25 | 1.0391 | 1.0169 | |
MCF 10A | Linsitinib | 0.0033113 | uM | 7 | 2500.00 | 469.42 | 11191.00 | 11060.25 | 1.0118 | 1.0052 |
MCF 10A | Linsitinib | 0.1 | uM | 7 | 2500.00 | 469.42 | 11265.00 | 11060.25 | 1.0185 | 1.0081 |
MCF 10A | Lapatinib | 0.31623 | uM | 7 | 2500.00 | 469.42 | 11048.00 | 11060.25 | 0.9989 | 0.9995 |
MCF 10A | Linsitinib | 0.031623 | uM | 7 | 2500.00 | 469.42 | 11150.00 | 11060.25 | 1.0081 | 1.0035 |
MCF 10A | 17-AAG | 10 | uM | 7 | 2500.00 | 469.42 | 727.00 | 11060.25 | 0.0657 | 0.1007 |
MCF 10A | Lapatinib | 0.1 | uM | 7 | 2500.00 | 469.42 | 11086.00 | 11060.25 | 1.0023 | 1.0010 |
MCF 10A | 17-AAG | 0.31623 | uM | 7 | 2500.00 | 469.42 | 641.00 | 11060.25 | 0.0580 | 0.0707 |
MCF 10A | Linsitinib | 10 | uM | 7 | 2500.00 | 469.42 | 3908.00 | 11060.25 | 0.3533 | 0.5919 |
MCF 10A | Linsitinib | 0.31623 | uM | 7 | 2500.00 | 469.42 | 8632.00 | 11060.25 | 0.7805 | 0.8942 |
MCF 10A | Erlotinib | 0.31623 | uM | 7 | 2500.00 | 469.42 | 5510.00 | 11060.25 | 0.4982 | 0.7165 |
MCF 10A | Erlotinib | 3.1623 | uM | 7 | 2500.00 | 469.42 | 845.00 | 11060.25 | 0.0764 | 0.1376 |