Breast Cancer Cell Density: Imaging assay of the density- and context-dependence of small molecule perturbagen response in breast cancer cell lines. Dataset 1 of 3: Cell count and normalized growth rate inhibition values. - Dataset (ID:20256)
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Cell | Small Molecule | Small Mol Concentration | Small Mol Conc Unit | Replicate | Seeding Density | Total Cell Count Before Treatment | Total Cell Count After Treatment | Total Control Cell Count | Relative Cell Count | Normalized Growth Rate Inhibition Value |
---|---|---|---|---|---|---|---|---|---|---|
MCF 10A | Etoposide | 0.31623 | uM | 5 | 1250.00 | 996.83 | 2870.00 | 10898.25 | 0.2634 | 0.3586 |
MCF 10A | PLX-4720 | 0.0033113 | uM | 5 | 1250.00 | 996.83 | 11102.00 | 10898.25 | 1.0187 | 1.0108 |
MCF 10A | NVP-TAE684 | 0.01 | uM | 5 | 1250.00 | 996.83 | 11088.00 | 10898.25 | 1.0174 | 1.0100 |
MCF 10A | Etoposide | 0.0033113 | uM | 5 | 1250.00 | 996.83 | 11269.00 | 10898.25 | 1.0340 | 1.0195 |
MCF 10A | PLX-4720 | 10 | uM | 5 | 1250.00 | 996.83 | 10712.00 | 10898.25 | 0.9829 | 0.9900 |
MCF 10A | Etoposide | 3.1623 | uM | 5 | 1250.00 | 996.83 | 944.00 | 10898.25 | 0.0866 | -0.0157 |
MCF 10A | Nilotinib | 19.9526 | uM | 5 | 1250.00 | 996.83 | 1085.00 | 10898.25 | 0.0996 | 0.0249 |
MCF 10A | Nilotinib | 0.1 | uM | 5 | 1250.00 | 996.83 | 10937.00 | 10898.25 | 1.0036 | 1.0021 |
MCF 10A | PLX-4720 | 0.1 | uM | 5 | 1250.00 | 996.83 | 11192.00 | 10898.25 | 1.0270 | 1.0155 |
MCF 10A | PLX-4720 | 1 | uM | 5 | 1250.00 | 996.83 | 11950.00 | 10898.25 | 1.0965 | 1.0541 |
MCF 10A | NVP-TAE684 | 0.1 | uM | 5 | 1250.00 | 996.83 | 9358.00 | 10898.25 | 0.8587 | 0.9136 |
MCF 10A | Nilotinib | 10 | uM | 5 | 1250.00 | 996.83 | 6756.00 | 10898.25 | 0.6199 | 0.7412 |
MCF 10A | Nilotinib | 0.01 | uM | 5 | 1250.00 | 996.83 | 10505.00 | 10898.25 | 0.9639 | 0.9788 |
MCF 10A | Etoposide | 19.9526 | uM | 5 | 1250.00 | 996.83 | 872.00 | 10898.25 | 0.0800 | -0.0380 |
MCF 10A | 0 | uM | 5 | 1250.00 | 996.83 | 10403.00 | 10898.25 | 0.9546 | 0.9732 | |
MCF 10A | 0 | uM | 5 | 1250.00 | 996.83 | 11202.00 | 10898.25 | 1.0279 | 1.0160 | |
MCF 10A | 0 | uM | 5 | 1250.00 | 996.83 | 11089.00 | 10898.25 | 1.0175 | 1.0101 | |
MCF 10A | 0 | uM | 5 | 1250.00 | 996.83 | 10756.00 | 10898.25 | 0.9870 | 0.9924 | |
MCF 10A | Etoposide | 1 | uM | 5 | 1250.00 | 996.83 | 1425.00 | 10898.25 | 0.1308 | 0.1091 |
MCF 10A | NVP-TAE684 | 0.0016596 | uM | 5 | 1250.00 | 996.83 | 10520.00 | 10898.25 | 0.9653 | 0.9796 |
MCF 10A | 0 | uM | 5 | 1250.00 | 996.83 | 10918.00 | 10898.25 | 1.0018 | 1.0010 | |
MCF 10A | NVP-TAE684 | 10 | uM | 5 | 1250.00 | 996.83 | 978.00 | 10898.25 | 0.0897 | -0.0055 |
MCF 10A | Nilotinib | 0.0033113 | uM | 5 | 1250.00 | 996.83 | 11533.00 | 10898.25 | 1.0582 | 1.0331 |
MCF 10A | NVP-TAE684 | 0.0033113 | uM | 5 | 1250.00 | 996.83 | 11045.00 | 10898.25 | 1.0135 | 1.0078 |
MCF 10A | Nilotinib | 0.31623 | uM | 5 | 1250.00 | 996.83 | 11077.00 | 10898.25 | 1.0164 | 1.0095 |