Breast Cancer Cell Density: Imaging assay of the density- and context-dependence of small molecule perturbagen response in breast cancer cell lines. Dataset 1 of 3: Cell count and normalized growth rate inhibition values. - Dataset (ID:20256)
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Cell | Small Molecule | Small Mol Concentration | Small Mol Conc Unit | Replicate | Seeding Density | Total Cell Count Before Treatment | Total Cell Count After Treatment | Total Control Cell Count | Relative Cell Count | Normalized Growth Rate Inhibition Value |
---|---|---|---|---|---|---|---|---|---|---|
MCF 10A | Etoposide | 0.0033113 | uM | 5 | 1250.00 | 996.83 | 11257.00 | 11026.75 | 1.0209 | 1.0120 |
MCF 10A | PLX-4720 | 19.9526 | uM | 5 | 1250.00 | 996.83 | 8170.00 | 11026.75 | 0.7409 | 0.8343 |
MCF 10A | Etoposide | 3.1623 | uM | 5 | 1250.00 | 996.83 | 926.00 | 11026.75 | 0.0840 | -0.0210 |
MCF 10A | NVP-TAE684 | 10 | uM | 5 | 1250.00 | 996.83 | 985.00 | 11026.75 | 0.0893 | -0.0034 |
MCF 10A | 0 | uM | 5 | 1250.00 | 996.83 | 11140.00 | 11026.75 | 1.0103 | 1.0059 | |
MCF 10A | 0 | uM | 5 | 1250.00 | 996.83 | 11587.00 | 11026.75 | 1.0508 | 1.0288 | |
MCF 10A | 0 | uM | 5 | 2500.00 | 2253.88 | 10889.00 | 10383.50 | 1.0487 | 1.0436 | |
MCF 10A | 0 | uM | 5 | 2500.00 | 2253.88 | 10182.00 | 10383.50 | 0.9806 | 0.9823 | |
MCF 10A | Etoposide | 10 | uM | 5 | 2500.00 | 2253.88 | 2012.00 | 10383.50 | 0.1938 | -0.0502 |
MCF 10A | 0 | uM | 5 | 2500.00 | 2253.88 | 10509.00 | 10383.50 | 1.0121 | 1.0109 | |
MCF 10A | 0 | uM | 5 | 2500.00 | 2253.88 | 10521.00 | 10383.50 | 1.0132 | 1.0120 | |
MCF 10A | Etoposide | 1 | uM | 5 | 2500.00 | 2253.88 | 2139.00 | 10383.50 | 0.2060 | -0.0235 |
MCF 10A | NVP-TAE684 | 0.31623 | uM | 5 | 2500.00 | 2253.88 | 7768.00 | 10383.50 | 0.7481 | 0.7532 |
MCF 10A | Nilotinib | 0.031623 | uM | 5 | 2500.00 | 2253.88 | 10541.00 | 10383.50 | 1.0152 | 1.0137 |
MCF 10A | Nilotinib | 3.1623 | uM | 5 | 2500.00 | 2253.88 | 10483.00 | 10383.50 | 1.0096 | 1.0087 |
MCF 10A | NVP-TAE684 | 0.01 | uM | 5 | 2500.00 | 2253.88 | 10157.00 | 10383.50 | 0.9782 | 0.9801 |
MCF 10A | NVP-TAE684 | 0.0033113 | uM | 5 | 2500.00 | 2253.88 | 10353.00 | 10383.50 | 0.9971 | 0.9973 |
MCF 10A | 0 | uM | 5 | 2500.00 | 2253.88 | 10376.00 | 10383.50 | 0.9993 | 0.9993 | |
MCF 10A | Etoposide | 0.1 | uM | 5 | 2500.00 | 2253.88 | 8024.00 | 10383.50 | 0.7728 | 0.7792 |
MCF 10A | PLX-4720 | 0.0033113 | uM | 5 | 2500.00 | 2253.88 | 10609.00 | 10383.50 | 1.0217 | 1.0196 |
MCF 10A | Nilotinib | 0.0033113 | uM | 5 | 2500.00 | 2253.88 | 10440.00 | 10383.50 | 1.0054 | 1.0049 |
MCF 10A | PLX-4720 | 0.31623 | uM | 5 | 2500.00 | 2253.88 | 10636.00 | 10383.50 | 1.0243 | 1.0219 |
MCF 10A | NVP-TAE684 | 0.031623 | uM | 5 | 2500.00 | 2253.88 | 9787.00 | 10383.50 | 0.9426 | 0.9470 |
MCF 10A | Nilotinib | 0.31623 | uM | 5 | 2500.00 | 2253.88 | 10703.00 | 10383.50 | 1.0308 | 1.0277 |
MCF 10A | NVP-TAE684 | 1 | uM | 5 | 2500.00 | 2253.88 | 6308.00 | 10383.50 | 0.6075 | 0.5952 |