Breast Cancer Cell Density: Imaging assay of the density- and context-dependence of small molecule perturbagen response in breast cancer cell lines. Dataset 1 of 3: Cell count and normalized growth rate inhibition values. - Dataset (ID:20256)
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Cell | Small Molecule | Small Mol Concentration | Small Mol Conc Unit | Replicate | Seeding Density | Total Cell Count Before Treatment | Total Cell Count After Treatment | Total Control Cell Count | Relative Cell Count | Normalized Growth Rate Inhibition Value |
---|---|---|---|---|---|---|---|---|---|---|
MCF 10A | Linsitinib | 0.1 | uM | 9 | 312.50 | 96.23 | 922.00 | 966.75 | 0.9537 | 0.9717 |
MCF 10A | Lapatinib | 0.031623 | uM | 9 | 312.50 | 96.23 | 508.00 | 966.75 | 0.5255 | 0.6485 |
MCF 10A | 17-AAG | 0.031623 | uM | 9 | 312.50 | 96.23 | 48.00 | 966.75 | 0.0497 | -0.1886 |
MCF 10A | 0 | uM | 9 | 312.50 | 96.23 | 771.00 | 966.75 | 0.7975 | 0.8686 | |
MCF 10A | 0 | uM | 9 | 625.00 | 186.95 | 2605.00 | 2943.00 | 0.8852 | 0.9396 | |
MCF 10A | 0 | uM | 9 | 625.00 | 186.95 | 2906.00 | 2943.00 | 0.9874 | 0.9937 | |
MCF 10A | Erlotinib | 0.0033113 | uM | 9 | 625.00 | 186.95 | 2659.00 | 2943.00 | 0.9035 | 0.9496 |
MCF 10A | 17-AAG | 0.001 | uM | 9 | 625.00 | 186.95 | 3167.00 | 2943.00 | 1.0761 | 1.0372 |
MCF 10A | 17-AAG | 0.000066069 | uM | 9 | 625.00 | 186.95 | 4072.00 | 2943.00 | 1.3836 | 1.1702 |
MCF 10A | Linsitinib | 3.1623 | uM | 9 | 625.00 | 186.95 | 1128.00 | 2943.00 | 0.3833 | 0.5714 |
MCF 10A | Erlotinib | 19.9526 | uM | 9 | 625.00 | 186.95 | 214.00 | 2943.00 | 0.0727 | 0.0346 |
MCF 10A | Lapatinib | 0.1 | uM | 9 | 625.00 | 186.95 | 3624.00 | 2943.00 | 1.2314 | 1.1075 |
MCF 10A | Lapatinib | 0.0016596 | uM | 9 | 625.00 | 186.95 | 3394.00 | 2943.00 | 1.1532 | 1.0730 |
MCF 10A | 0 | uM | 9 | 625.00 | 186.95 | 3627.00 | 2943.00 | 1.2324 | 1.1079 | |
MCF 10A | 17-AAG | 0.1 | uM | 9 | 625.00 | 186.95 | 183.00 | 2943.00 | 0.0622 | -0.0054 |
MCF 10A | Erlotinib | 0.1 | uM | 9 | 625.00 | 186.95 | 3713.00 | 2943.00 | 1.2616 | 1.1204 |
MCF 10A | Lapatinib | 0.31623 | uM | 9 | 625.00 | 186.95 | 3576.00 | 2943.00 | 1.2151 | 1.1004 |
MCF 10A | Linsitinib | 0.31623 | uM | 9 | 625.00 | 186.95 | 2868.00 | 2943.00 | 0.9745 | 0.9871 |
MCF 10A | Lapatinib | 0.01 | uM | 9 | 625.00 | 186.95 | 3845.00 | 2943.00 | 1.3065 | 1.1391 |
MCF 10A | Linsitinib | 0.031623 | uM | 9 | 625.00 | 186.95 | 3360.00 | 2943.00 | 1.1417 | 1.0678 |
MCF 10A | Erlotinib | 0.031623 | uM | 9 | 625.00 | 186.95 | 3311.00 | 2943.00 | 1.1250 | 1.0601 |
MCF 10A | Erlotinib | 1 | uM | 9 | 625.00 | 186.95 | 283.00 | 2943.00 | 0.0962 | 0.1099 |
MCF 10A | 17-AAG | 0.000302 | uM | 9 | 625.00 | 186.95 | 3137.00 | 2943.00 | 1.0659 | 1.0324 |
MCF 10A | Lapatinib | 3.1623 | uM | 9 | 625.00 | 186.95 | 918.00 | 2943.00 | 0.3119 | 0.4921 |
MCF 10A | 17-AAG | 0.31623 | uM | 9 | 625.00 | 186.95 | 99.00 | 2943.00 | 0.0336 | -0.1478 |